Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome?
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/8035 |
Resumo: | Depression is a mental disorder that can affect people of any age group, of such complexity that it is necessary to have a specialist to evaluate and analyze each case, since it can be caused either by physiological changes or by external factors, or both. Concomitantly with psychological assistance, the use of antidepressants is indicated, with Selective Serotonin Reuptake Inhibitors (SSRIs) being the most used; therefore, the objective of this article is to discuss the effects of the discontinuation syndrome and/or dependence among SSRIs. A quantitative study of narrative bibliographic review was made using scientific articles from the last 16 years (2004-2020). The databases Medline, The Cochrane Library Database, Lilacs, PubMed, SciELO, Research Gate, Science Direct, PePSIC were used. The following terms were searched as descriptors: dependency syndrome, abstinence syndrome, depression, selective serotonin reuptake inhibitors, antidepressants and the Boolean AND. It is noted that doctors increasingly prescribe the use of SSRIs, as they have fewer side effects, but it is necessary to take precautions when dealing with drug interactions. For a person to become dependent on a substance, it is necessary to meet three of the six criteria established by the International Classification of Diseases (ICD-10) (1992), and, as discussed throughout the work, it does not occur with the correct use of antidepressants. However, the discontinuation syndrome can be caused by the rapid withdrawal of these drugs, requiring extra attention from the doctor at the end of treatment. |
id |
UNIFEI_36db3856793a2386cfc93cf9c4f814bd |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/8035 |
network_acronym_str |
UNIFEI |
network_name_str |
Research, Society and Development |
repository_id_str |
|
spelling |
Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome?Inhibidores selectivos de la recaptación de serotonina en el tratamiento de la depresión: ¿síndrome de discontinuación y/o dependencia?Inibidores seletivos de recaptação de serotonina no tratamento da depressão: síndrome de descontinuação e/ou de dependência?Síndrome de dependênciaSíndrome de abstinênciaDepressãoAntidepressivosInibidores seletivos da recaptação de serotonina.Dependence syndromeWithdrawal syndromeDepressionAntidepressantsSelective serotonin reuptake inhibitors.Síndrome de dependenciaSíndrome de abstinenciaDepresiónAntidepresivosInhibidores selectivos de la recaptación de serotonina. Depression is a mental disorder that can affect people of any age group, of such complexity that it is necessary to have a specialist to evaluate and analyze each case, since it can be caused either by physiological changes or by external factors, or both. Concomitantly with psychological assistance, the use of antidepressants is indicated, with Selective Serotonin Reuptake Inhibitors (SSRIs) being the most used; therefore, the objective of this article is to discuss the effects of the discontinuation syndrome and/or dependence among SSRIs. A quantitative study of narrative bibliographic review was made using scientific articles from the last 16 years (2004-2020). The databases Medline, The Cochrane Library Database, Lilacs, PubMed, SciELO, Research Gate, Science Direct, PePSIC were used. The following terms were searched as descriptors: dependency syndrome, abstinence syndrome, depression, selective serotonin reuptake inhibitors, antidepressants and the Boolean AND. It is noted that doctors increasingly prescribe the use of SSRIs, as they have fewer side effects, but it is necessary to take precautions when dealing with drug interactions. For a person to become dependent on a substance, it is necessary to meet three of the six criteria established by the International Classification of Diseases (ICD-10) (1992), and, as discussed throughout the work, it does not occur with the correct use of antidepressants. However, the discontinuation syndrome can be caused by the rapid withdrawal of these drugs, requiring extra attention from the doctor at the end of treatment.La depresión es un trastorno mental que puede afectar a personas de cualquier grupo de edad, de tal complejidad que es necesario contar con un especialista que lo evalúe para analizar cada caso, ya que puede ser provocado por cambios fisiológicos o por factores externos, o ambos. Concomitantemente con la asistencia psicológica, está indicado el uso de antidepresivos, siendo los inhibidores selectivos de la recaptación de serotonina (ISRS) los más utilizados; por lo tanto, el propósito de este artículo es discutir los efectos del síndrome de discontinuación y/o dependencia entre los ISRS. Se realizó un estudio cuantitativo de revisión bibliográfica narrativa utilizando artículos científicos de los últimos 16 años (2004-2020). Se utilizaron las bases de datos Medline, The Cochrane Library Database, Lilacs, PubMed, SciELO, Research Gate, Science Direct, PePSIC. Se buscaron los siguientes términos como descriptores: síndrome de dependencia, síndrome de abstinencia, depresión, inhibidores selectivos de la recaptación de serotonina, antidepresivos y el AND booleano. Se observa que los médicos prescriben cada vez más el uso de ISRS, ya que tienen menos efectos secundarios, pero es necesario tomar precauciones cuando se trata de interacciones medicamentosas. Para que una persona se vuelva dependiente de una sustancia, es necesario cumplir con tres de los seis criterios establecidos por la Clasificación Internacional de Enfermedades (CIE-10) (1992) y, como se comenta a lo largo del trabajo, no ocurre con el uso correcto de antidepresivos. Sin embargo, el síndrome de suspensión puede ser causado por la suspensión rápida de estos medicamentos, lo que requiere atención adicional por parte del médico al final del tratamiento.Depressão é um transtorno mental passível de acometer pessoas em qualquer faixa etária, de tamanha complexidade que se torna necessária a avaliação de um especialista para analisar cada caso, já que pode ser causada tanto por alterações fisiológicas quanto por fatores externos, ou ambos. Concomitantemente com a assistência psicológica, é indicado o uso de antidepressivos, sendo os Inibidores Seletivos de Recaptação de Serotonina (ISRS) os mais utilizados; sendo assim, o objetivo deste artigo é discorrer sobre os efeitos de síndrome de descontinuação e/ou dependência entre os ISRSs. Foi feito um estudo quantitativo de revisão bibliográfica narrativa usando-se artigos científicos dos últimos 16 anos (2004-2020). Foram utilizados os bancos de dados Medline, The Cochrane Library Database, Lilacs, PubMed, SciELO, Research Gate, Science Direct, PePSIC. Pesquisaram-se como descritores os seguintes termos: síndrome de dependência, síndrome de abstinência, depressão, inibidores seletivos da recaptação de serotonina, antidepressivos e o booleano AND. Nota-se que os médicos receitam cada vez mais o uso de ISRS, por possuírem menos efeitos colaterais, mas é necessário tomar precauções ao se tratar de interação medicamentosa. Para que uma pessoa se torne dependente de uma substância, é necessário atender três dos seis critérios estabelecidos pela Classificação Internacional de Doenças (CID-10) (1992), e, como discorrido ao longo do trabalho, não ocorre com o uso correto de antidepressivos. Entretanto, a síndrome de descontinuação pode ser provocada pela rápida retirada desses medicamentos, exigindo atenção extra do médico no fim do tratamento.Research, Society and Development2020-09-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/803510.33448/rsd-v9i9.8035Research, Society and Development; Vol. 9 No. 9; e815998035Research, Society and Development; Vol. 9 Núm. 9; e815998035Research, Society and Development; v. 9 n. 9; e8159980352525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/8035/7083Copyright (c) 2020 Mariana Eduarda Demarchi; Daniel Del Nero Casselli; Gabriela Martins Figueira; Eduardo de Sousa Martins e Silva; José Carlos Souzahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessDemarchi, Mariana EduardaCasselli, Daniel Del Nero Figueira, Gabriela Martins Silva, Eduardo de Sousa Martins e Souza, José Carlos 2020-09-18T01:42:11Zoai:ojs.pkp.sfu.ca:article/8035Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:30:36.314777Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome? Inhibidores selectivos de la recaptación de serotonina en el tratamiento de la depresión: ¿síndrome de discontinuación y/o dependencia? Inibidores seletivos de recaptação de serotonina no tratamento da depressão: síndrome de descontinuação e/ou de dependência? |
title |
Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome? |
spellingShingle |
Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome? Demarchi, Mariana Eduarda Síndrome de dependência Síndrome de abstinência Depressão Antidepressivos Inibidores seletivos da recaptação de serotonina. Dependence syndrome Withdrawal syndrome Depression Antidepressants Selective serotonin reuptake inhibitors. Síndrome de dependencia Síndrome de abstinencia Depresión Antidepresivos Inhibidores selectivos de la recaptación de serotonina. |
title_short |
Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome? |
title_full |
Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome? |
title_fullStr |
Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome? |
title_full_unstemmed |
Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome? |
title_sort |
Selective serotonin reuptake inhibitors in the treatment of depression: discontinuation and/or dependency syndrome? |
author |
Demarchi, Mariana Eduarda |
author_facet |
Demarchi, Mariana Eduarda Casselli, Daniel Del Nero Figueira, Gabriela Martins Silva, Eduardo de Sousa Martins e Souza, José Carlos |
author_role |
author |
author2 |
Casselli, Daniel Del Nero Figueira, Gabriela Martins Silva, Eduardo de Sousa Martins e Souza, José Carlos |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Demarchi, Mariana Eduarda Casselli, Daniel Del Nero Figueira, Gabriela Martins Silva, Eduardo de Sousa Martins e Souza, José Carlos |
dc.subject.por.fl_str_mv |
Síndrome de dependência Síndrome de abstinência Depressão Antidepressivos Inibidores seletivos da recaptação de serotonina. Dependence syndrome Withdrawal syndrome Depression Antidepressants Selective serotonin reuptake inhibitors. Síndrome de dependencia Síndrome de abstinencia Depresión Antidepresivos Inhibidores selectivos de la recaptación de serotonina. |
topic |
Síndrome de dependência Síndrome de abstinência Depressão Antidepressivos Inibidores seletivos da recaptação de serotonina. Dependence syndrome Withdrawal syndrome Depression Antidepressants Selective serotonin reuptake inhibitors. Síndrome de dependencia Síndrome de abstinencia Depresión Antidepresivos Inhibidores selectivos de la recaptación de serotonina. |
description |
Depression is a mental disorder that can affect people of any age group, of such complexity that it is necessary to have a specialist to evaluate and analyze each case, since it can be caused either by physiological changes or by external factors, or both. Concomitantly with psychological assistance, the use of antidepressants is indicated, with Selective Serotonin Reuptake Inhibitors (SSRIs) being the most used; therefore, the objective of this article is to discuss the effects of the discontinuation syndrome and/or dependence among SSRIs. A quantitative study of narrative bibliographic review was made using scientific articles from the last 16 years (2004-2020). The databases Medline, The Cochrane Library Database, Lilacs, PubMed, SciELO, Research Gate, Science Direct, PePSIC were used. The following terms were searched as descriptors: dependency syndrome, abstinence syndrome, depression, selective serotonin reuptake inhibitors, antidepressants and the Boolean AND. It is noted that doctors increasingly prescribe the use of SSRIs, as they have fewer side effects, but it is necessary to take precautions when dealing with drug interactions. For a person to become dependent on a substance, it is necessary to meet three of the six criteria established by the International Classification of Diseases (ICD-10) (1992), and, as discussed throughout the work, it does not occur with the correct use of antidepressants. However, the discontinuation syndrome can be caused by the rapid withdrawal of these drugs, requiring extra attention from the doctor at the end of treatment. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-09-08 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/8035 10.33448/rsd-v9i9.8035 |
url |
https://rsdjournal.org/index.php/rsd/article/view/8035 |
identifier_str_mv |
10.33448/rsd-v9i9.8035 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/8035/7083 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 9; e815998035 Research, Society and Development; Vol. 9 Núm. 9; e815998035 Research, Society and Development; v. 9 n. 9; e815998035 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052780526960640 |