Evaluation of the antimicrobial potential of the Ethanolic extract of Cecropia pachystachya t. (Embaúba) Leaves

• Autor(a) principal: Andrade, Beatriz Rayana Damásio de
• Data de Publicação: 2021
• Outros Autores: Silva, Athila da Costa, Souza, Jaqueline Barbosa de, Silva, Luana Bastos da, Silva, Mayara Paes de França, Alves, Rayssa Rosendo, Silva, Maria Luiza Ribeiro Bastos da
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/18679
• topic: Atividade antibacteriana; Atividade antifúngica; Inibição; Produto bioativo.; Actividad antibacteriana; Actividad antifúngica; Inhibición; Producto bioactivo.; Antibacterial activity; Antifungal activity; Inhibition; Bioactive product.

The present study aims to evaluate the antimicrobial potential of the ethanol extract of Cecropia pachystachya (embaúba) leaves. To achieve the microbiological tests used were Gram-positive bacteria S. aureus ATCC 29213, S. aureus ATCC 25925, S. pyogenes 1033B and the clinical isolate from the Mycology Laboratory of the Federal University of Pernambuco, C. albicans 7098. The extract was prepared using the newly collected material (5:10; p/v) in ethanolic solution with concentrations of 50 and 70%, remaining in contact with the solvent for 72 hours. After the period, the eluent was filtered, stored and kept in a refrigerator at 4°C until use. The evaluation of antibacterial activity was carried out in triplicate by agar diffusion technique and to perform the tests, the strains were recovered on Nutritive Agar (NA) and incubated in an oven at 35 ± 2 ºC for 24h. For the analysis of the inhibitory activity of the extracts, the diameters of the inhibition halos (mm) were read. The extract from Embaúba demonstrated activity against the tested bacterial strains, whose results obtained were halos that ranged from 12mm to 18mm. However, more in vitro and in vivo studies are needed to evaluate the compounds present in the extract in isolation in order to elucidate the antimicrobial activity, considering the possibility of the development of drugs with spectrum of action against Gram-positive bacteria and yeasts.