Cognition in Chagas disease: A systematic review

Detalhes bibliográficos
Autor(a) principal: Santos, Natalia Ligabô dos
Data de Publicação: 2021
Outros Autores: Reis, Laysa Rodrigues dos, Rodrigues, Felipe Viegas
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/17549
Resumo: Chagas disease (CD) is transmitted by the hemoflagellate parasite Trypanosoma cruzi and manifests itself acutely and chronically, when it is characterized as indeterminate, cardiac, digestive or mixed. Some patients with Chagas' disease (CD) have cognitive alterations and there are three hypotheses about cognitive damage: (I) neurological and cognitive alterations caused by the cardiac form, (II) after the acute form there is the spontaneous disappearance of the clinical signs of disease with cognitive manifestations remaining, (III) cognitive and neurological manifestations are caused by chronic infection. The aim of the present study was to carry out a systematic review of the literature to verify measurable cognitive impairments in Chagas patients. The articles were searched in the Pubmed and Embase databases, with the descriptors "Chagas disease" and "cognition". All articles with assessment of cognitive aspects of patients with CD were included. One hundred and ninety-seven articles were found, three of which met the criteria. All articles demonstrate cognitive impairments related to CD, in a chronic form, with impairment of both general intelligence and long-term memory, in addition to a deficit in the execution time of the tests.
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spelling Cognition in Chagas disease: A systematic reviewCognición en la enfermedad de Chagas: Una revisión sistemáticaCognição na doença de Chagas: Uma revisão sistemáticaCognitionChagas diseaseExecutive functionSystematic reviewMemory disorders.CogniciónLa enfermedad de ChagasFunción ejecutivaRevisión sistemáticaTrastornos de la memoria.CogniçãoDoença de ChagasFunção executivaRevisão sistemáticaTranstornos de memória.Chagas disease (CD) is transmitted by the hemoflagellate parasite Trypanosoma cruzi and manifests itself acutely and chronically, when it is characterized as indeterminate, cardiac, digestive or mixed. Some patients with Chagas' disease (CD) have cognitive alterations and there are three hypotheses about cognitive damage: (I) neurological and cognitive alterations caused by the cardiac form, (II) after the acute form there is the spontaneous disappearance of the clinical signs of disease with cognitive manifestations remaining, (III) cognitive and neurological manifestations are caused by chronic infection. The aim of the present study was to carry out a systematic review of the literature to verify measurable cognitive impairments in Chagas patients. The articles were searched in the Pubmed and Embase databases, with the descriptors "Chagas disease" and "cognition". All articles with assessment of cognitive aspects of patients with CD were included. One hundred and ninety-seven articles were found, three of which met the criteria. All articles demonstrate cognitive impairments related to CD, in a chronic form, with impairment of both general intelligence and long-term memory, in addition to a deficit in the execution time of the tests.La enfermedad de Chagas (EC) es transmitida por el parásito hemoflagelado Trypanosoma cruzi y se manifiesta inicialmente de forma aguda y luego permanece en la forma crónica, cuando se caracteriza por ser indeterminada, cardíaca, digestiva o mixta. Algunos pacientes con enfermedad de Chagas (EC) presentan cambios cognitivos y existen tres hipótesis sobre el daño cognitivo: (I) cambios neurológicos y cognitivos provocados como consecuencia de la forma cardíaca, (II) después de la forma aguda hay una desaparición espontánea de la clínica. signos de enfermedad restantes manifestaciones cognitivas, (III) las manifestaciones cognitivas y neurológicas son causadas por una infección crónica. El objetivo de este estudio fue realizar una revisión sistemática de la literatura para verificar el deterioro cognitivo medible en pacientes chagásicos. Los artículos fueron buscados en las bases de datos Pubmed y Embase, con los descriptores “enfermedad de Chagas” y “cognición”. Se incluyeron artículos que evaluaban aspectos cognitivos de pacientes con EC. Se encontraron ciento noventa y siete artículos, tres de los cuales cumplieron con los criterios. Todos los artículos demuestran un deterioro cognitivo relacionado con la EC, de forma crónica, con deterioro tanto de la inteligencia general como de la memoria a largo plazo, además de un déficit en el tiempo de ejecución de la prueba.A doença de Chagas (DC) é transmitida pelo parasita hemoflagelado Trypanosoma cruzi e manifesta-se inicialmente de forma aguda e, depois, permanece na forma crônica, quando é caracterizada como indeterminada, cardíaca, digestiva ou mista. Alguns pacientes com doença de Chagas (DC) apresentam alterações cognitivas e há três hipóteses sobre os danos cognitivos: (I) alterações neurológicas e cognitivas causadas por consequência da forma cardíaca, (II) após a forma aguda há o desaparecimento espontâneo dos sinais clínicos da doença permanecendo as manifestações cognitivas, (III) as manifestações cognitivas e neurológicas são causadas por infecção crônica. O objetivo do presente trabalho foi fazer uma revisão sistemática da literatura para verificar os prejuízos cognitivos mensuráveis em pacientes chagásicos. Os artigos foram pesquisados nas bases Pubmed e Embase, com os descritores “Chagas disease” e “cognition”. Foram incluídos artigos com mensuração de aspectos cognitivos de pacientes com a DC. Foram encontrados cento e noventa e sete artigos, três dos quais atendiam aos critérios. Todos os artigos demonstram prejuízos cognitivos relacionados à DC, forma crônica, com comprometimento tanto da inteligência geral quanto da memória de longa-duração, além de déficit no tempo de execução dos testes.Research, Society and Development2021-07-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1754910.33448/rsd-v10i9.17549Research, Society and Development; Vol. 10 No. 9; e3710917549Research, Society and Development; Vol. 10 Núm. 9; e3710917549Research, Society and Development; v. 10 n. 9; e37109175492525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/17549/15871Copyright (c) 2021 Natalia Ligabô dos Santos; Laysa Rodrigues dos Reis; Felipe Viegas Rodrigueshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Natalia Ligabô dos Reis, Laysa Rodrigues dosRodrigues, Felipe Viegas2021-09-12T14:28:06Zoai:ojs.pkp.sfu.ca:article/17549Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:37:52.245428Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Cognition in Chagas disease: A systematic review
Cognición en la enfermedad de Chagas: Una revisión sistemática
Cognição na doença de Chagas: Uma revisão sistemática
title Cognition in Chagas disease: A systematic review
spellingShingle Cognition in Chagas disease: A systematic review
Santos, Natalia Ligabô dos
Cognition
Chagas disease
Executive function
Systematic review
Memory disorders.
Cognición
La enfermedad de Chagas
Función ejecutiva
Revisión sistemática
Trastornos de la memoria.
Cognição
Doença de Chagas
Função executiva
Revisão sistemática
Transtornos de memória.
title_short Cognition in Chagas disease: A systematic review
title_full Cognition in Chagas disease: A systematic review
title_fullStr Cognition in Chagas disease: A systematic review
title_full_unstemmed Cognition in Chagas disease: A systematic review
title_sort Cognition in Chagas disease: A systematic review
author Santos, Natalia Ligabô dos
author_facet Santos, Natalia Ligabô dos
Reis, Laysa Rodrigues dos
Rodrigues, Felipe Viegas
author_role author
author2 Reis, Laysa Rodrigues dos
Rodrigues, Felipe Viegas
author2_role author
author
dc.contributor.author.fl_str_mv Santos, Natalia Ligabô dos
Reis, Laysa Rodrigues dos
Rodrigues, Felipe Viegas
dc.subject.por.fl_str_mv Cognition
Chagas disease
Executive function
Systematic review
Memory disorders.
Cognición
La enfermedad de Chagas
Función ejecutiva
Revisión sistemática
Trastornos de la memoria.
Cognição
Doença de Chagas
Função executiva
Revisão sistemática
Transtornos de memória.
topic Cognition
Chagas disease
Executive function
Systematic review
Memory disorders.
Cognición
La enfermedad de Chagas
Función ejecutiva
Revisión sistemática
Trastornos de la memoria.
Cognição
Doença de Chagas
Função executiva
Revisão sistemática
Transtornos de memória.
description Chagas disease (CD) is transmitted by the hemoflagellate parasite Trypanosoma cruzi and manifests itself acutely and chronically, when it is characterized as indeterminate, cardiac, digestive or mixed. Some patients with Chagas' disease (CD) have cognitive alterations and there are three hypotheses about cognitive damage: (I) neurological and cognitive alterations caused by the cardiac form, (II) after the acute form there is the spontaneous disappearance of the clinical signs of disease with cognitive manifestations remaining, (III) cognitive and neurological manifestations are caused by chronic infection. The aim of the present study was to carry out a systematic review of the literature to verify measurable cognitive impairments in Chagas patients. The articles were searched in the Pubmed and Embase databases, with the descriptors "Chagas disease" and "cognition". All articles with assessment of cognitive aspects of patients with CD were included. One hundred and ninety-seven articles were found, three of which met the criteria. All articles demonstrate cognitive impairments related to CD, in a chronic form, with impairment of both general intelligence and long-term memory, in addition to a deficit in the execution time of the tests.
publishDate 2021
dc.date.none.fl_str_mv 2021-07-20
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/17549
10.33448/rsd-v10i9.17549
url https://rsdjournal.org/index.php/rsd/article/view/17549
identifier_str_mv 10.33448/rsd-v10i9.17549
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/17549/15871
dc.rights.driver.fl_str_mv Copyright (c) 2021 Natalia Ligabô dos Santos; Laysa Rodrigues dos Reis; Felipe Viegas Rodrigues
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Natalia Ligabô dos Santos; Laysa Rodrigues dos Reis; Felipe Viegas Rodrigues
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 9; e3710917549
Research, Society and Development; Vol. 10 Núm. 9; e3710917549
Research, Society and Development; v. 10 n. 9; e3710917549
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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