Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| DOI: | 10.33448/rsd-v10i16.22773 |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/22773 |
Resumo: | This study aimed to analyse the safety and efficacy of bacterial cellulose (CB) produced from sugarcane molasses, through studies conducted and published by the Sugarcane Biopolymers Research Group, POLISA©, Biopolymers for Health. This is a narrative review of the literature that was conducted from the collection of publications on sugarcane biopolymers, linked to POLISA©, Biopolymers for Health researchers. Twenty one studies published between the years 2002 to 2020 were selected, of which 11 studies related to pre-clinical evaluation and 10 to clinical evaluation. Studies involving toxicological and biocompatibility assessments described the safety and risks related to the use of CB, while those of clinical evaluation investigated the healing process and tissue remodelling, and estimated its effectiveness as a dressing. In conclusion, CB did not prove to be cytotoxic, genotoxic or acutely toxic, showing high biocompatibility, in addition, it proved to be effective in inducing the healing process and tissue remodeling. |
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Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review Seguridad y eficacia de la celulosa bacteriana obtenida de la melaza de caña de azúcar en el proceso de cicatrización y remodelación tisular: una revisión narrativa Segurança e eficácia da celulose bacteriana obtida a partir do melaço de cana-de-açúcar no processo de cicatrização e remodelamento tecidual: uma revisão narrativaBiopolymersEquipment safetyEfficacyWound healing.BiopolimeroSeguridad de equiposEficáciaCicatrización de heridas.BiopolímerosSegurança de equipamentosEficáciaCicatrização.This study aimed to analyse the safety and efficacy of bacterial cellulose (CB) produced from sugarcane molasses, through studies conducted and published by the Sugarcane Biopolymers Research Group, POLISA©, Biopolymers for Health. This is a narrative review of the literature that was conducted from the collection of publications on sugarcane biopolymers, linked to POLISA©, Biopolymers for Health researchers. Twenty one studies published between the years 2002 to 2020 were selected, of which 11 studies related to pre-clinical evaluation and 10 to clinical evaluation. Studies involving toxicological and biocompatibility assessments described the safety and risks related to the use of CB, while those of clinical evaluation investigated the healing process and tissue remodelling, and estimated its effectiveness as a dressing. In conclusion, CB did not prove to be cytotoxic, genotoxic or acutely toxic, showing high biocompatibility, in addition, it proved to be effective in inducing the healing process and tissue remodeling.Este estudio analizó la seguridad y eficacia de la celulosa bacteriana (CB) producida a partir de la melaza de caña de azúcar, a través de estudios realizados y publicados por el Grupo de Investigación de Biopolímeros de Caña de Azúcar, vinculado a POLISA© ©, Biopolímeros para la Salud. Se trata de una revisión narrativa de la literatura que se realizó desde el colección de publicaciones sobre biopolímero de caña de azúcar, vinculado a POLISA©, Biopolímeros para la Salud. Se seleccionaron 21 estudios publicados entre los años 2002 a 2020, de los cuales 11 estudios relacionados con la evaluación preclínica y 10 con la evaluación clínica. Los estudios que involucraron evaluaciones toxicológicas y de biocompatibilidad describieron la seguridad y los riesgos que enfrenta el uso del CB, mientras que los de evaluación clínica investigaron el proceso de curación y remodelación tisular y estimaron su efectividad como apósito. En general, el CB bacteriana no resultó ser citotóxico, genotóxico o agudamente tóxico, presentando alta biocompatibilidad, además, demostró ser efectivo en inducir el proceso de cicatrización y remodelación tisular.Este estudo teve como objetivo analisar a segurança e eficácia da celulose bacteriana (CB) produzida a partir do melaço de cana-de- açúcar, através de estudos conduzidos e publicados pelo Grupo de Pesquisa sobre Biopolímeros de Cana-de-Açúcar, vinculados à POLISA©, Biopolímeros para Saúde. Trata-se de uma revisão narrativa da literatura que foi conduzida a partir do acervo de publicações sobre biopolímero de cana-de-açúcar, vinculados à POLISA©, Biopolímeros para Saúde. Foram selecionados 21 estudos publicados entre os anos de 2002 a 2020, sendo 11 estudos relacionados à avaliação pré-clínica e 10 à avaliação clínica. Os estudos envolvendo a avaliação toxicológica e de biocompatibilidade descreveram a segurança e os riscos frente ao uso da CB, enquanto que os de avaliação clínica investigaram o processo de cicatrização e remodelamento tecidual, a fim de estimar a sua eficácia como curativo. De modo geral, a CB não demonstrou ser citotóxico, genotóxico ou agudamente tóxico, apresentando alta biocompatibilidade, além disso, mostrou-se eficaz ao induzir o processo de cicatrização e remodelamento tecidual.Research, Society and Development2021-12-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2277310.33448/rsd-v10i16.22773Research, Society and Development; Vol. 10 No. 16; e50101622773Research, Society and Development; Vol. 10 Núm. 16; e50101622773Research, Society and Development; v. 10 n. 16; e501016227732525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/22773/20708Copyright (c) 2021 Lara Emanuele Santana Santos; Rafaela de Siqueira Ferraz Carvalho; Kelly Monteiro dos Santos ; René Duarte Martins; Flávia Cristina Morone Pintohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Lara Emanuele SantanaCarvalho, Rafaela de Siqueira FerrazSantos , Kelly Monteiro dosMartins, René DuartePinto, Flávia Cristina Morone2021-12-20T11:03:07Zoai:ojs.pkp.sfu.ca:article/22773Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:41:50.742447Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review Seguridad y eficacia de la celulosa bacteriana obtenida de la melaza de caña de azúcar en el proceso de cicatrización y remodelación tisular: una revisión narrativa Segurança e eficácia da celulose bacteriana obtida a partir do melaço de cana-de-açúcar no processo de cicatrização e remodelamento tecidual: uma revisão narrativa |
| title |
Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review |
| spellingShingle |
Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review Santos, Lara Emanuele Santana Biopolymers Equipment safety Efficacy Wound healing. Biopolimero Seguridad de equipos Eficácia Cicatrización de heridas. Biopolímeros Segurança de equipamentos Eficácia Cicatrização. Santos, Lara Emanuele Santana Biopolymers Equipment safety Efficacy Wound healing. Biopolimero Seguridad de equipos Eficácia Cicatrización de heridas. Biopolímeros Segurança de equipamentos Eficácia Cicatrização. |
| title_short |
Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review |
| title_full |
Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review |
| title_fullStr |
Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review |
| title_full_unstemmed |
Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review |
| title_sort |
Safety and efficacy of bacterial cellulose obtained from sugarcane molasses in the healing and tissue remodeling process: a narrative review |
| author |
Santos, Lara Emanuele Santana |
| author_facet |
Santos, Lara Emanuele Santana Santos, Lara Emanuele Santana Carvalho, Rafaela de Siqueira Ferraz Santos , Kelly Monteiro dos Martins, René Duarte Pinto, Flávia Cristina Morone Carvalho, Rafaela de Siqueira Ferraz Santos , Kelly Monteiro dos Martins, René Duarte Pinto, Flávia Cristina Morone |
| author_role |
author |
| author2 |
Carvalho, Rafaela de Siqueira Ferraz Santos , Kelly Monteiro dos Martins, René Duarte Pinto, Flávia Cristina Morone |
| author2_role |
author author author author |
| dc.contributor.author.fl_str_mv |
Santos, Lara Emanuele Santana Carvalho, Rafaela de Siqueira Ferraz Santos , Kelly Monteiro dos Martins, René Duarte Pinto, Flávia Cristina Morone |
| dc.subject.por.fl_str_mv |
Biopolymers Equipment safety Efficacy Wound healing. Biopolimero Seguridad de equipos Eficácia Cicatrización de heridas. Biopolímeros Segurança de equipamentos Eficácia Cicatrização. |
| topic |
Biopolymers Equipment safety Efficacy Wound healing. Biopolimero Seguridad de equipos Eficácia Cicatrización de heridas. Biopolímeros Segurança de equipamentos Eficácia Cicatrização. |
| description |
This study aimed to analyse the safety and efficacy of bacterial cellulose (CB) produced from sugarcane molasses, through studies conducted and published by the Sugarcane Biopolymers Research Group, POLISA©, Biopolymers for Health. This is a narrative review of the literature that was conducted from the collection of publications on sugarcane biopolymers, linked to POLISA©, Biopolymers for Health researchers. Twenty one studies published between the years 2002 to 2020 were selected, of which 11 studies related to pre-clinical evaluation and 10 to clinical evaluation. Studies involving toxicological and biocompatibility assessments described the safety and risks related to the use of CB, while those of clinical evaluation investigated the healing process and tissue remodelling, and estimated its effectiveness as a dressing. In conclusion, CB did not prove to be cytotoxic, genotoxic or acutely toxic, showing high biocompatibility, in addition, it proved to be effective in inducing the healing process and tissue remodeling. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-12-06 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/22773 10.33448/rsd-v10i16.22773 |
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https://rsdjournal.org/index.php/rsd/article/view/22773 |
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10.33448/rsd-v10i16.22773 |
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por |
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por |
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https://rsdjournal.org/index.php/rsd/article/view/22773/20708 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 10 No. 16; e50101622773 Research, Society and Development; Vol. 10 Núm. 16; e50101622773 Research, Society and Development; v. 10 n. 16; e50101622773 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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10.33448/rsd-v10i16.22773 |