Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis

Detalhes bibliográficos
Autor(a) principal: Dantas, Emanuelle Paiva de Vasconcelos
Data de Publicação: 2020
Outros Autores: Martignago, Cintia Cristina Santi, Tim, Carla Roberta, Barros Filho, Ricardo João Soares, Neves, Tereza Mara Alcântara, Assis, Lívia
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/9024
Resumo: Sepsis is considered a major health problem, with acute lung injury (ALI) being one of the most serious complications of septic shock. It is known that an ALI is a disease characterized by damage to the alveolar epithelium, infiltration of inflammatory cells, increased permeability of the alveolar - capillary barrier, interstitial edema that cause an imbalance in the condition and pulmonary perfusion, with a high morbidity rate and in the units intensive care. The treatment of ALI has a high cost and is often not sufficiently effective and, therefore, the search for new therapies is of extreme clinical importance. Photobiomodulation (PBM) through lasers and LEDs has to be a promising tool with good results for several inflammatory diseases, including changes that affect the respiratory system. Within this context, the objective of this study is to provide, through a narrative review, an understanding of the current available evidence on the importance of PBM in the treatment of respiratory disorders and its possible applicability in ALI due to sepsis. The searches were performed in the bibliographic databases of PubMed / MEDLINE, Virtual Health Library (VHL), Web of Science and SciELO. The evidence found in this study points out that PBM can be proposed as a support for conventional medical therapy in the treatment of ALI arising from sepsis, due to the potential to prevent the progression of lung parenchyma injury, attenuate the inflammatory condition, reduction process and reduce the recovery time of the patient with APL due to sepsis.
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spelling Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsisFotobiomodulación como coadyuvante en el tratamiento de la lesión pulmonar aguda por sepsisFotobiomodulação como coadjuvante no tratamento na lesão pulmonar aguda decorrente da sepsePhototherapyLasersSepsisLung injuryRehabilitation.FototerapiaLáseresSepticemiaLesión pulmonarRehabilitación.FototerapiaLasersSepseLesão pulmonarReabilitação.Sepsis is considered a major health problem, with acute lung injury (ALI) being one of the most serious complications of septic shock. It is known that an ALI is a disease characterized by damage to the alveolar epithelium, infiltration of inflammatory cells, increased permeability of the alveolar - capillary barrier, interstitial edema that cause an imbalance in the condition and pulmonary perfusion, with a high morbidity rate and in the units intensive care. The treatment of ALI has a high cost and is often not sufficiently effective and, therefore, the search for new therapies is of extreme clinical importance. Photobiomodulation (PBM) through lasers and LEDs has to be a promising tool with good results for several inflammatory diseases, including changes that affect the respiratory system. Within this context, the objective of this study is to provide, through a narrative review, an understanding of the current available evidence on the importance of PBM in the treatment of respiratory disorders and its possible applicability in ALI due to sepsis. The searches were performed in the bibliographic databases of PubMed / MEDLINE, Virtual Health Library (VHL), Web of Science and SciELO. The evidence found in this study points out that PBM can be proposed as a support for conventional medical therapy in the treatment of ALI arising from sepsis, due to the potential to prevent the progression of lung parenchyma injury, attenuate the inflammatory condition, reduction process and reduce the recovery time of the patient with APL due to sepsis.La sepsis se considera un problema de salud importante, y la lesión pulmonar aguda (LPA) es una de las complicaciones más graves del shock séptico. Se sabe que una LPA es una enfermedad caracterizada por daño al epitelio alveolar, infiltración de células inflamatorias, aumento de la permeabilidad de la barrera alveolocapilar, edema intersticial que provocan un desequilibrio en la condición y perfusión pulmonar, con una alta tasa de morbilidad y en las unidades. cuidados intensivos. El tratamiento de la LPA tiene un coste elevado y muchas veces no es lo suficientemente eficaz y, por tanto, la búsqueda de nuevas terapias es de extrema importancia clínica. La fotobiomodulación (PBM) a través de láseres y LED tiene que ser una herramienta prometedora con buenos resultados para varias enfermedades inflamatorias, incluidos los cambios que afectan al sistema respiratorio. En este contexto, el objetivo de este estudio es proporcionar, a través de una revisión narrativa, una comprensión de la evidencia disponible actualmente sobre la importancia de la PBM en el tratamiento de los trastornos respiratorios y su posible aplicabilidad en la LPA por sepsis. Las búsquedas se realizaron en las bases de datos bibliográficas de PubMed / MEDLINE, Virtual Health Library (VHL), Web of Science y SciELO. La evidencia encontrada en este estudio apunta a que el PBM puede proponerse como soporte de la terapia médica convencional en el tratamiento de la LPA derivada de la sepsis, debido al potencial de prevenir la progresión de la lesión del parénquima pulmonar, atenuar la condición inflamatoria, optimizar el proceso de reducción y reducir el tiempo de recuperación del paciente con LPA por sepsis.A sepse é considerada um grande problema de saúde, sendo a lesão pulmonar aguda (LPA) uma das complicações mais graves do choque séptico. Sabe-se que a LPA é uma doença caracterizada por lesão no epitélio alveolar, infiltrado de células inflamatórias, aumento da permeabilidade da barreira alvéolo – capilar, edema intersticial que ocasionam um desequilíbrio na ventilação e perfusão pulmonar, com alta taxa de morbidade e mortalidade nas unidades de terapia intensiva. O tratamento da LPA possui custo elevado e muitas vezes não é suficientemente eficaz, desta forma, a busca por novas terapias são de extrema importância clínica. A fotobiomodulação (PBM) através de lasers e LEDs tem mostrado ser uma ferramenta promissora e com bons resultados para diversas doenças inflamatórias, incluindo as alterações que acometem o sistema respiratório. Dentro deste contexto, o objetivo deste estudo é proporcionar, através de uma revisão narrativa, uma compreensão das evidências atuais disponíveis sobre a importância da PBM no tratamento dos distúrbios respiratórios e sua possível aplicabilidade na LPA decorrente da sepse. As buscas foram realizadas nas bases de dados bibliográficas do PubMed/MEDLINE, Biblioteca virtual da saúde (BVS), Web of Science e SciELO. As evidências encontradas neste estudo direcionam que a PBM pode ser proposta como um suporte para a terapia médica convencional no tratamento LPA oriundas da sepse, devido ao potencial de prevenir a progressão da lesão do parênquima pulmonar, atenuar o quadro inflamatório, otimizar o processo de reparação e reduzir o tempo de recuperação do paciente com LPA decorrente da sepse.Research, Society and Development2020-10-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/902410.33448/rsd-v9i10.9024Research, Society and Development; Vol. 9 No. 10; e5929109024Research, Society and Development; Vol. 9 Núm. 10; e5929109024Research, Society and Development; v. 9 n. 10; e59291090242525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/9024/7966Copyright (c) 2020 Emanuelle Paiva de Vasconcelos Dantas; Cintia Cristina Santi Martignago; Carla Roberta Tim; Ricardo João Soares Barros Filho; Tereza Mara Alcântara Neves; Lívia Assishttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessDantas, Emanuelle Paiva de Vasconcelos Martignago, Cintia Cristina Santi Tim, Carla RobertaBarros Filho, Ricardo João Soares Neves, Tereza Mara Alcântara Assis, Lívia 2020-10-31T12:03:23Zoai:ojs.pkp.sfu.ca:article/9024Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:31:22.268370Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis
Fotobiomodulación como coadyuvante en el tratamiento de la lesión pulmonar aguda por sepsis
Fotobiomodulação como coadjuvante no tratamento na lesão pulmonar aguda decorrente da sepse
title Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis
spellingShingle Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis
Dantas, Emanuelle Paiva de Vasconcelos
Phototherapy
Lasers
Sepsis
Lung injury
Rehabilitation.
Fototerapia
Láseres
Septicemia
Lesión pulmonar
Rehabilitación.
Fototerapia
Lasers
Sepse
Lesão pulmonar
Reabilitação.
title_short Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis
title_full Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis
title_fullStr Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis
title_full_unstemmed Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis
title_sort Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis
author Dantas, Emanuelle Paiva de Vasconcelos
author_facet Dantas, Emanuelle Paiva de Vasconcelos
Martignago, Cintia Cristina Santi
Tim, Carla Roberta
Barros Filho, Ricardo João Soares
Neves, Tereza Mara Alcântara
Assis, Lívia
author_role author
author2 Martignago, Cintia Cristina Santi
Tim, Carla Roberta
Barros Filho, Ricardo João Soares
Neves, Tereza Mara Alcântara
Assis, Lívia
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Dantas, Emanuelle Paiva de Vasconcelos
Martignago, Cintia Cristina Santi
Tim, Carla Roberta
Barros Filho, Ricardo João Soares
Neves, Tereza Mara Alcântara
Assis, Lívia
dc.subject.por.fl_str_mv Phototherapy
Lasers
Sepsis
Lung injury
Rehabilitation.
Fototerapia
Láseres
Septicemia
Lesión pulmonar
Rehabilitación.
Fototerapia
Lasers
Sepse
Lesão pulmonar
Reabilitação.
topic Phototherapy
Lasers
Sepsis
Lung injury
Rehabilitation.
Fototerapia
Láseres
Septicemia
Lesión pulmonar
Rehabilitación.
Fototerapia
Lasers
Sepse
Lesão pulmonar
Reabilitação.
description Sepsis is considered a major health problem, with acute lung injury (ALI) being one of the most serious complications of septic shock. It is known that an ALI is a disease characterized by damage to the alveolar epithelium, infiltration of inflammatory cells, increased permeability of the alveolar - capillary barrier, interstitial edema that cause an imbalance in the condition and pulmonary perfusion, with a high morbidity rate and in the units intensive care. The treatment of ALI has a high cost and is often not sufficiently effective and, therefore, the search for new therapies is of extreme clinical importance. Photobiomodulation (PBM) through lasers and LEDs has to be a promising tool with good results for several inflammatory diseases, including changes that affect the respiratory system. Within this context, the objective of this study is to provide, through a narrative review, an understanding of the current available evidence on the importance of PBM in the treatment of respiratory disorders and its possible applicability in ALI due to sepsis. The searches were performed in the bibliographic databases of PubMed / MEDLINE, Virtual Health Library (VHL), Web of Science and SciELO. The evidence found in this study points out that PBM can be proposed as a support for conventional medical therapy in the treatment of ALI arising from sepsis, due to the potential to prevent the progression of lung parenchyma injury, attenuate the inflammatory condition, reduction process and reduce the recovery time of the patient with APL due to sepsis.
publishDate 2020
dc.date.none.fl_str_mv 2020-10-09
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/9024
10.33448/rsd-v9i10.9024
url https://rsdjournal.org/index.php/rsd/article/view/9024
identifier_str_mv 10.33448/rsd-v9i10.9024
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/9024/7966
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 10; e5929109024
Research, Society and Development; Vol. 9 Núm. 10; e5929109024
Research, Society and Development; v. 9 n. 10; e5929109024
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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