Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/9024 |
Resumo: | Sepsis is considered a major health problem, with acute lung injury (ALI) being one of the most serious complications of septic shock. It is known that an ALI is a disease characterized by damage to the alveolar epithelium, infiltration of inflammatory cells, increased permeability of the alveolar - capillary barrier, interstitial edema that cause an imbalance in the condition and pulmonary perfusion, with a high morbidity rate and in the units intensive care. The treatment of ALI has a high cost and is often not sufficiently effective and, therefore, the search for new therapies is of extreme clinical importance. Photobiomodulation (PBM) through lasers and LEDs has to be a promising tool with good results for several inflammatory diseases, including changes that affect the respiratory system. Within this context, the objective of this study is to provide, through a narrative review, an understanding of the current available evidence on the importance of PBM in the treatment of respiratory disorders and its possible applicability in ALI due to sepsis. The searches were performed in the bibliographic databases of PubMed / MEDLINE, Virtual Health Library (VHL), Web of Science and SciELO. The evidence found in this study points out that PBM can be proposed as a support for conventional medical therapy in the treatment of ALI arising from sepsis, due to the potential to prevent the progression of lung parenchyma injury, attenuate the inflammatory condition, reduction process and reduce the recovery time of the patient with APL due to sepsis. |
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Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsisFotobiomodulación como coadyuvante en el tratamiento de la lesión pulmonar aguda por sepsisFotobiomodulação como coadjuvante no tratamento na lesão pulmonar aguda decorrente da sepsePhototherapyLasersSepsisLung injuryRehabilitation.FototerapiaLáseresSepticemiaLesión pulmonarRehabilitación.FototerapiaLasersSepseLesão pulmonarReabilitação.Sepsis is considered a major health problem, with acute lung injury (ALI) being one of the most serious complications of septic shock. It is known that an ALI is a disease characterized by damage to the alveolar epithelium, infiltration of inflammatory cells, increased permeability of the alveolar - capillary barrier, interstitial edema that cause an imbalance in the condition and pulmonary perfusion, with a high morbidity rate and in the units intensive care. The treatment of ALI has a high cost and is often not sufficiently effective and, therefore, the search for new therapies is of extreme clinical importance. Photobiomodulation (PBM) through lasers and LEDs has to be a promising tool with good results for several inflammatory diseases, including changes that affect the respiratory system. Within this context, the objective of this study is to provide, through a narrative review, an understanding of the current available evidence on the importance of PBM in the treatment of respiratory disorders and its possible applicability in ALI due to sepsis. The searches were performed in the bibliographic databases of PubMed / MEDLINE, Virtual Health Library (VHL), Web of Science and SciELO. The evidence found in this study points out that PBM can be proposed as a support for conventional medical therapy in the treatment of ALI arising from sepsis, due to the potential to prevent the progression of lung parenchyma injury, attenuate the inflammatory condition, reduction process and reduce the recovery time of the patient with APL due to sepsis.La sepsis se considera un problema de salud importante, y la lesión pulmonar aguda (LPA) es una de las complicaciones más graves del shock séptico. Se sabe que una LPA es una enfermedad caracterizada por daño al epitelio alveolar, infiltración de células inflamatorias, aumento de la permeabilidad de la barrera alveolocapilar, edema intersticial que provocan un desequilibrio en la condición y perfusión pulmonar, con una alta tasa de morbilidad y en las unidades. cuidados intensivos. El tratamiento de la LPA tiene un coste elevado y muchas veces no es lo suficientemente eficaz y, por tanto, la búsqueda de nuevas terapias es de extrema importancia clínica. La fotobiomodulación (PBM) a través de láseres y LED tiene que ser una herramienta prometedora con buenos resultados para varias enfermedades inflamatorias, incluidos los cambios que afectan al sistema respiratorio. En este contexto, el objetivo de este estudio es proporcionar, a través de una revisión narrativa, una comprensión de la evidencia disponible actualmente sobre la importancia de la PBM en el tratamiento de los trastornos respiratorios y su posible aplicabilidad en la LPA por sepsis. Las búsquedas se realizaron en las bases de datos bibliográficas de PubMed / MEDLINE, Virtual Health Library (VHL), Web of Science y SciELO. La evidencia encontrada en este estudio apunta a que el PBM puede proponerse como soporte de la terapia médica convencional en el tratamiento de la LPA derivada de la sepsis, debido al potencial de prevenir la progresión de la lesión del parénquima pulmonar, atenuar la condición inflamatoria, optimizar el proceso de reducción y reducir el tiempo de recuperación del paciente con LPA por sepsis.A sepse é considerada um grande problema de saúde, sendo a lesão pulmonar aguda (LPA) uma das complicações mais graves do choque séptico. Sabe-se que a LPA é uma doença caracterizada por lesão no epitélio alveolar, infiltrado de células inflamatórias, aumento da permeabilidade da barreira alvéolo – capilar, edema intersticial que ocasionam um desequilíbrio na ventilação e perfusão pulmonar, com alta taxa de morbidade e mortalidade nas unidades de terapia intensiva. O tratamento da LPA possui custo elevado e muitas vezes não é suficientemente eficaz, desta forma, a busca por novas terapias são de extrema importância clínica. A fotobiomodulação (PBM) através de lasers e LEDs tem mostrado ser uma ferramenta promissora e com bons resultados para diversas doenças inflamatórias, incluindo as alterações que acometem o sistema respiratório. Dentro deste contexto, o objetivo deste estudo é proporcionar, através de uma revisão narrativa, uma compreensão das evidências atuais disponíveis sobre a importância da PBM no tratamento dos distúrbios respiratórios e sua possível aplicabilidade na LPA decorrente da sepse. As buscas foram realizadas nas bases de dados bibliográficas do PubMed/MEDLINE, Biblioteca virtual da saúde (BVS), Web of Science e SciELO. As evidências encontradas neste estudo direcionam que a PBM pode ser proposta como um suporte para a terapia médica convencional no tratamento LPA oriundas da sepse, devido ao potencial de prevenir a progressão da lesão do parênquima pulmonar, atenuar o quadro inflamatório, otimizar o processo de reparação e reduzir o tempo de recuperação do paciente com LPA decorrente da sepse.Research, Society and Development2020-10-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/902410.33448/rsd-v9i10.9024Research, Society and Development; Vol. 9 No. 10; e5929109024Research, Society and Development; Vol. 9 Núm. 10; e5929109024Research, Society and Development; v. 9 n. 10; e59291090242525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/9024/7966Copyright (c) 2020 Emanuelle Paiva de Vasconcelos Dantas; Cintia Cristina Santi Martignago; Carla Roberta Tim; Ricardo João Soares Barros Filho; Tereza Mara Alcântara Neves; Lívia Assishttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessDantas, Emanuelle Paiva de Vasconcelos Martignago, Cintia Cristina Santi Tim, Carla RobertaBarros Filho, Ricardo João Soares Neves, Tereza Mara Alcântara Assis, Lívia 2020-10-31T12:03:23Zoai:ojs.pkp.sfu.ca:article/9024Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:31:22.268370Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis Fotobiomodulación como coadyuvante en el tratamiento de la lesión pulmonar aguda por sepsis Fotobiomodulação como coadjuvante no tratamento na lesão pulmonar aguda decorrente da sepse |
title |
Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis |
spellingShingle |
Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis Dantas, Emanuelle Paiva de Vasconcelos Phototherapy Lasers Sepsis Lung injury Rehabilitation. Fototerapia Láseres Septicemia Lesión pulmonar Rehabilitación. Fototerapia Lasers Sepse Lesão pulmonar Reabilitação. |
title_short |
Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis |
title_full |
Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis |
title_fullStr |
Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis |
title_full_unstemmed |
Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis |
title_sort |
Photobiomodulation as an adjunct in the treatment of acute lung injury due to sepsis |
author |
Dantas, Emanuelle Paiva de Vasconcelos |
author_facet |
Dantas, Emanuelle Paiva de Vasconcelos Martignago, Cintia Cristina Santi Tim, Carla Roberta Barros Filho, Ricardo João Soares Neves, Tereza Mara Alcântara Assis, Lívia |
author_role |
author |
author2 |
Martignago, Cintia Cristina Santi Tim, Carla Roberta Barros Filho, Ricardo João Soares Neves, Tereza Mara Alcântara Assis, Lívia |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Dantas, Emanuelle Paiva de Vasconcelos Martignago, Cintia Cristina Santi Tim, Carla Roberta Barros Filho, Ricardo João Soares Neves, Tereza Mara Alcântara Assis, Lívia |
dc.subject.por.fl_str_mv |
Phototherapy Lasers Sepsis Lung injury Rehabilitation. Fototerapia Láseres Septicemia Lesión pulmonar Rehabilitación. Fototerapia Lasers Sepse Lesão pulmonar Reabilitação. |
topic |
Phototherapy Lasers Sepsis Lung injury Rehabilitation. Fototerapia Láseres Septicemia Lesión pulmonar Rehabilitación. Fototerapia Lasers Sepse Lesão pulmonar Reabilitação. |
description |
Sepsis is considered a major health problem, with acute lung injury (ALI) being one of the most serious complications of septic shock. It is known that an ALI is a disease characterized by damage to the alveolar epithelium, infiltration of inflammatory cells, increased permeability of the alveolar - capillary barrier, interstitial edema that cause an imbalance in the condition and pulmonary perfusion, with a high morbidity rate and in the units intensive care. The treatment of ALI has a high cost and is often not sufficiently effective and, therefore, the search for new therapies is of extreme clinical importance. Photobiomodulation (PBM) through lasers and LEDs has to be a promising tool with good results for several inflammatory diseases, including changes that affect the respiratory system. Within this context, the objective of this study is to provide, through a narrative review, an understanding of the current available evidence on the importance of PBM in the treatment of respiratory disorders and its possible applicability in ALI due to sepsis. The searches were performed in the bibliographic databases of PubMed / MEDLINE, Virtual Health Library (VHL), Web of Science and SciELO. The evidence found in this study points out that PBM can be proposed as a support for conventional medical therapy in the treatment of ALI arising from sepsis, due to the potential to prevent the progression of lung parenchyma injury, attenuate the inflammatory condition, reduction process and reduce the recovery time of the patient with APL due to sepsis. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-10-09 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/9024 10.33448/rsd-v9i10.9024 |
url |
https://rsdjournal.org/index.php/rsd/article/view/9024 |
identifier_str_mv |
10.33448/rsd-v9i10.9024 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/9024/7966 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 10; e5929109024 Research, Society and Development; Vol. 9 Núm. 10; e5929109024 Research, Society and Development; v. 9 n. 10; e5929109024 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052661346861056 |