Relationship of intravascular coagulation disseminated by D-dimer determination with COVID-19: an integrative review

• Autor(a) principal: Silva, Mariana Lessi
• Data de Publicação: 2022
• Outros Autores: Alves, Igor de Oliveira Bezerra, Ribeiro, Carolina Heitmann Mares Azevedo, Lo Prete, Ana Cristina
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/25731
• topic: COVID-19; Disseminated intravascular coagulation; Prognosis.; COVID-19; Coagulación intravascular diseminada; Pronóstico.; COVID-19; Coagulação intravascular disseminada; Prognóstico.

Severe acute respiratory syndrome caused by COVID-19 has recently been reported in Wuhan, the capital of the Chinese province of Hubei. The disease can manifest itself in severe ways, in some of these cases, conditions of hypercoagulability have been identified followed by hematological changes. This work is an integrative review that assesses the relationship between intravascular coagulation disseminated by the determination of D-dimer and COVID-19 and correlates this marker as a possible prognosis of the disease. During the study it was possible to show that the increase in D-dimer may be associated with greater severity of COVID-19 and / or mortality, observed by the increase in the occurrence of ICD, including studies in patients who evolved to thrombotic conditions, such as DVT, VTE and pulmonary embolism. In addition, such an association in other conditions that increase coagulation, as in the case of type 2 diabetic patients and in patients who used ECMO.