Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloring

Detalhes bibliográficos
Autor(a) principal: Silva, Lucas Albuquerque Rosendo da
Data de Publicação: 2022
Outros Autores: Santos, Renata Andrea dos, Mendonça, Rafael de Souza, Sá, Antônio Vinícius Pinho, Andrade, Rosileide Fontenele da Silva, Rodríguez, Dayana Montero, Campos-Takaki, Galba Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/27078
Resumo: Prodigiosin is a microbial red pigment, mainly produced by the bacterium Serratia marcescens, considered as a promising antimicrobial, immunosuppressive and antiproliferative compound. However, its industrial commercialization is still limited because of the high cost of production mainly due to the use of expensive substrates. Hence, this work aimed to the sustainable production of prodigiosin by S. marcescens UCP 1549, using corn bran as alternative and low-cost substrate, and its application in soap coloring. According to the results, both bacterial growth and red pigment production occurred, achieving 7.24 g/L and 1.68 g/L of biomass and pigment yield, respectively. Positive result in the presumptive test indicated red pigment as prodigiosin, which was confirmed by UV-Visible spectrophotometry (maximum absorbance peak at 535 nm), TLC (Rf 0.9) and the functional groups identified by FTIR spectroscopy. Prodigiosin showed color stability at different pH values and NaCl concentration. The application of pigment in soap coloring was effective, suggesting its promising potential in the cosmetics industry as natural colorant. The results showed the biotechnological potential of S. marcescens UCP 1549 in the biotransformation of corn bran into prodigiosin, allowing a more economically and competitively industrial bioprocess.
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spelling Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloringProducción rentable de prodigiosina estable por Serratia marcescens UCP 1549 y aplicación en la coloración de jabónProdução econômica de prodigiosina estável por Serratia marcescens UCP 1549 e aplicação na coloração de sabonetePigmento naturalFarelo de milhoIndústria cosmética.Pigmento naturalSalvado de maízIndustria cosmética.Natural pigmentCorn branCosmetics industry.Prodigiosin is a microbial red pigment, mainly produced by the bacterium Serratia marcescens, considered as a promising antimicrobial, immunosuppressive and antiproliferative compound. However, its industrial commercialization is still limited because of the high cost of production mainly due to the use of expensive substrates. Hence, this work aimed to the sustainable production of prodigiosin by S. marcescens UCP 1549, using corn bran as alternative and low-cost substrate, and its application in soap coloring. According to the results, both bacterial growth and red pigment production occurred, achieving 7.24 g/L and 1.68 g/L of biomass and pigment yield, respectively. Positive result in the presumptive test indicated red pigment as prodigiosin, which was confirmed by UV-Visible spectrophotometry (maximum absorbance peak at 535 nm), TLC (Rf 0.9) and the functional groups identified by FTIR spectroscopy. Prodigiosin showed color stability at different pH values and NaCl concentration. The application of pigment in soap coloring was effective, suggesting its promising potential in the cosmetics industry as natural colorant. The results showed the biotechnological potential of S. marcescens UCP 1549 in the biotransformation of corn bran into prodigiosin, allowing a more economically and competitively industrial bioprocess.La prodigiosina es un pigmento microbiano rojo, producido principalmente por la bacteria Serratia marcescens, considerado un promisorio compuesto antimicrobiano, inmunosupresor y antiproliferativo. Sin embargo, su comercialización industrial aún es limitada debido al alto costo de producción, causado principalmente por el uso de sustratos costosos. Así, este trabajo tuvo como objetivo la producción sustentable de prodigiosina por S. marcescens UCP 1549, utilizando salvado de maíz como sustrato alternativo y de bajo costo, y su aplicación en la coloración de jabón. De acuerdo con los resultados, se produjo tanto el crecimiento bacteriano como la producción de pigmento rojo, alcanzando 7,24 g/L de biomasa y 1,68 g/L de rendimiento de pigmento, respectivamente. El resultado positivo en la prueba presuntiva indicó que el pigmento rojo era prodigiosina, lo que fue confirmado por espectrofotometría UV-Visible (pico máximo de absorbancia a 535 nm), TLC (Rf 0,9) y los grupos funcionales identificados por espectroscopia FTIR. La prodigiosina mostró estabilidad de color a diferentes valores de pH y concentración de NaCl. La aplicación del pigmento en la coloración de jabón fue eficiente, sugiriendo su promisorio potencial como colorante natural en la industria cosmética. Los resultados mostraron el potencial biotecnológico de S. marcescens UCP 1549 en la biotransformación de salvado de maíz en prodigiosina, permitiendo un bioproceso industrial más económico y competitivo.A prodigiosina é um pigmento microbiano vermelho, produzido principalmente pela bactéria Serratia marcescens, considerado um promissor composto antimicrobiano, imunossupressor e antiproliferativo. Contudo, sua comercialização industrial ainda é limitada devido ao alto custo de produção, causado principalmente pelo uso de substratos caros. Assim, este trabalho teve como objetivo a produção sustentável de prodigiosina por S. marcescens UCP 1549, utilizando farelo de milho como substrato alternativo e de baixo custo, e sua aplicação na coloração de sabonete. De acordo com os resultados, ocorreu crescimento bacteriano e produção de pigmento vermelho, atingindo 7,24 g/L de biomassa e 1,68 g/L de rendimento de pigmento, respectivamente. O resultado positivo no teste presuntivo indicou o pigmento vermelho como prodigiosina, o que foi confirmado por espectrofotometria UV-Visível (pico de absorbância máxima em 535 nm), TLC (Rf 0,9) e os grupos funcionais identificados por espectroscopia FTIR. A prodigiosina apresentou estabilidade na cor em diferentes valores de pH e concentração de NaCl. A aplicação do pigmento na coloração do sabonete foi eficiente, sugerindo seu potencial promissor como corante natural na indústria cosmética. Os resultados mostraram o potencial biotecnológico de S. marcescens UCP 1549 na biotransformação do farelo de milho em prodigiosina, permitindo um bioprocesso industrial mais econômico e competitivo.Research, Society and Development2022-03-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2707810.33448/rsd-v11i4.27078Research, Society and Development; Vol. 11 No. 4; e9711427078Research, Society and Development; Vol. 11 Núm. 4; e9711427078Research, Society and Development; v. 11 n. 4; e97114270782525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/27078/23995Copyright (c) 2022 Lucas Albuquerque Rosendo da Silva; Renata Andrea dos Santos; Rafael de Souza Mendonça; Antônio Vinícius Pinho Sá; Rosileide Fontenele da Silva Andrade; Dayana Montero Rodríguez; Galba Maria Campos-Takakihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Lucas Albuquerque Rosendo da Santos, Renata Andrea dos Mendonça, Rafael de Souza Sá, Antônio Vinícius Pinho Andrade, Rosileide Fontenele da SilvaRodríguez, Dayana Montero Campos-Takaki, Galba Maria2022-03-27T17:17:09Zoai:ojs.pkp.sfu.ca:article/27078Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:55.096121Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloring
Producción rentable de prodigiosina estable por Serratia marcescens UCP 1549 y aplicación en la coloración de jabón
Produção econômica de prodigiosina estável por Serratia marcescens UCP 1549 e aplicação na coloração de sabonete
title Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloring
spellingShingle Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloring
Silva, Lucas Albuquerque Rosendo da
Pigmento natural
Farelo de milho
Indústria cosmética.
Pigmento natural
Salvado de maíz
Industria cosmética.
Natural pigment
Corn bran
Cosmetics industry.
title_short Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloring
title_full Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloring
title_fullStr Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloring
title_full_unstemmed Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloring
title_sort Cost-effective production of stable prodigiosin by Serratia marcescens UCP 1549 and application in soap coloring
author Silva, Lucas Albuquerque Rosendo da
author_facet Silva, Lucas Albuquerque Rosendo da
Santos, Renata Andrea dos
Mendonça, Rafael de Souza
Sá, Antônio Vinícius Pinho
Andrade, Rosileide Fontenele da Silva
Rodríguez, Dayana Montero
Campos-Takaki, Galba Maria
author_role author
author2 Santos, Renata Andrea dos
Mendonça, Rafael de Souza
Sá, Antônio Vinícius Pinho
Andrade, Rosileide Fontenele da Silva
Rodríguez, Dayana Montero
Campos-Takaki, Galba Maria
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Lucas Albuquerque Rosendo da
Santos, Renata Andrea dos
Mendonça, Rafael de Souza
Sá, Antônio Vinícius Pinho
Andrade, Rosileide Fontenele da Silva
Rodríguez, Dayana Montero
Campos-Takaki, Galba Maria
dc.subject.por.fl_str_mv Pigmento natural
Farelo de milho
Indústria cosmética.
Pigmento natural
Salvado de maíz
Industria cosmética.
Natural pigment
Corn bran
Cosmetics industry.
topic Pigmento natural
Farelo de milho
Indústria cosmética.
Pigmento natural
Salvado de maíz
Industria cosmética.
Natural pigment
Corn bran
Cosmetics industry.
description Prodigiosin is a microbial red pigment, mainly produced by the bacterium Serratia marcescens, considered as a promising antimicrobial, immunosuppressive and antiproliferative compound. However, its industrial commercialization is still limited because of the high cost of production mainly due to the use of expensive substrates. Hence, this work aimed to the sustainable production of prodigiosin by S. marcescens UCP 1549, using corn bran as alternative and low-cost substrate, and its application in soap coloring. According to the results, both bacterial growth and red pigment production occurred, achieving 7.24 g/L and 1.68 g/L of biomass and pigment yield, respectively. Positive result in the presumptive test indicated red pigment as prodigiosin, which was confirmed by UV-Visible spectrophotometry (maximum absorbance peak at 535 nm), TLC (Rf 0.9) and the functional groups identified by FTIR spectroscopy. Prodigiosin showed color stability at different pH values and NaCl concentration. The application of pigment in soap coloring was effective, suggesting its promising potential in the cosmetics industry as natural colorant. The results showed the biotechnological potential of S. marcescens UCP 1549 in the biotransformation of corn bran into prodigiosin, allowing a more economically and competitively industrial bioprocess.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-20
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27078
10.33448/rsd-v11i4.27078
url https://rsdjournal.org/index.php/rsd/article/view/27078
identifier_str_mv 10.33448/rsd-v11i4.27078
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27078/23995
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 4; e9711427078
Research, Society and Development; Vol. 11 Núm. 4; e9711427078
Research, Society and Development; v. 11 n. 4; e9711427078
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052835222781952

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