The use of tenofovir and alteration of kidney function in people living with HIV/AIDS

Detalhes bibliográficos
Autor(a) principal: Freire, Ananda Soares de Brito
Data de Publicação: 2022
Outros Autores: Andrade Filho, Francisco de Assis Oliveira, Carvalho, Carlos Gilvan Nunes de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/24502
Resumo: This study aims to analyze the alteration in the renal function of PLHIV who used Tenofovir as part of their antiretroviral treatment. This was an observational epidemiological study, through a review of 86 records of PLHIV using Tenofovir, where a survey of data on creatinine values of patients was carried out. A data collection form covering demographic, clinical and laboratory data was used. The estimated Glomerular Filtration Rate was calculated by the CKD-EPI formula. With the results of this study, it was observed that so far, there are no medications free of adverse effects, but it was seen that in addition to monitoring the renal function of patients, it is necessary to prioritize the control of the patient's underlying diseases, as well as the maintenance of an undetectable viral load, a fact that was found in this study, when using TDF as ARVT.
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spelling The use of tenofovir and alteration of kidney function in people living with HIV/AIDSEl uso de tenofovir y la alteración de la función renal en personas que viven con VIH/SIDAO uso do tenofovir e alteração da função renal em pessoas vivendo com HIV/AIDSHIVCreatininaTenofovir.HIVCreatinineTenofovir.VIHCreatininaTenofovir.This study aims to analyze the alteration in the renal function of PLHIV who used Tenofovir as part of their antiretroviral treatment. This was an observational epidemiological study, through a review of 86 records of PLHIV using Tenofovir, where a survey of data on creatinine values of patients was carried out. A data collection form covering demographic, clinical and laboratory data was used. The estimated Glomerular Filtration Rate was calculated by the CKD-EPI formula. With the results of this study, it was observed that so far, there are no medications free of adverse effects, but it was seen that in addition to monitoring the renal function of patients, it is necessary to prioritize the control of the patient's underlying diseases, as well as the maintenance of an undetectable viral load, a fact that was found in this study, when using TDF as ARVT.Este estudio tiene como objetivo analizar la alteración en la función renal de las PVVIH que usaron Tenofovir como parte de su tratamiento antirretroviral. Se trata de un estudio epidemiológico observacional, a través de una revisión de 86 registros de PVVIH utilizando Tenofovir, donde se realizó una encuesta de datos sobre los valores de creatinina de los pacientes. Se utilizó un formulario de recopilación de datos que incluía datos demográficos, clínicos y de laboratorio. La tasa de filtración glomerular estimada se calculó mediante la fórmula CKD-EPI. Con los resultados de este estudio, se observó que hasta el momento, no existen medicamentos libres de efectos adversos, pero se vio que además de monitorear la función renal de los pacientes, es necesario priorizar el control de las enfermedades de base del paciente, así como el mantenimiento de una carga viral indetectable, hecho que se encontró en este estudio, al utilizar TDF como TAR.Este estudo tem como objetivo analisar a alteração da função renal de PVHIV que fizeram uso de Tenofovir como parte do tratamento antirretroviral. Tratou-se de um estudo epidemiológico observacional, por meio da revisão de 86 prontuários de PVHIV em uso de Tenofovir, onde foi realizado um levantamento dos dados sobre valores de creatinina dos pacientes. Foi utilizado uma ficha de coleta de dados abrangendo dados demográficos, clínicos e laboratoriais. A Taxa de Filtração Glomerular estimada foi calculada pela fórmula CKD-EPI. Com os resultados deste estudo, observou-se que até o momento, não existem medicações isentas de efeitos adversos, porém viu-se que além de monitorar a função renal dos pacientes, é preciso priorizar o controle das doenças de base do paciente, assim como a manutenção da carga viral indetectável, fato que foi encontrado neste estudo, ao se utilizar o TDF como TARV.Research, Society and Development2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2450210.33448/rsd-v11i1.24502Research, Society and Development; Vol. 11 No. 1; e4911124502Research, Society and Development; Vol. 11 Núm. 1; e4911124502Research, Society and Development; v. 11 n. 1; e49111245022525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/24502/21616Copyright (c) 2022 Ananda Soares de Brito Freire; Francisco de Assis Oliveira Andrade Filho; Carlos Gilvan Nunes de Carvalhohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFreire, Ananda Soares de BritoAndrade Filho, Francisco de Assis OliveiraCarvalho, Carlos Gilvan Nunes de2022-01-16T18:08:18Zoai:ojs.pkp.sfu.ca:article/24502Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:43:01.989043Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv The use of tenofovir and alteration of kidney function in people living with HIV/AIDS
El uso de tenofovir y la alteración de la función renal en personas que viven con VIH/SIDA
O uso do tenofovir e alteração da função renal em pessoas vivendo com HIV/AIDS
title The use of tenofovir and alteration of kidney function in people living with HIV/AIDS
spellingShingle The use of tenofovir and alteration of kidney function in people living with HIV/AIDS
Freire, Ananda Soares de Brito
HIV
Creatinina
Tenofovir.
HIV
Creatinine
Tenofovir.
VIH
Creatinina
Tenofovir.
title_short The use of tenofovir and alteration of kidney function in people living with HIV/AIDS
title_full The use of tenofovir and alteration of kidney function in people living with HIV/AIDS
title_fullStr The use of tenofovir and alteration of kidney function in people living with HIV/AIDS
title_full_unstemmed The use of tenofovir and alteration of kidney function in people living with HIV/AIDS
title_sort The use of tenofovir and alteration of kidney function in people living with HIV/AIDS
author Freire, Ananda Soares de Brito
author_facet Freire, Ananda Soares de Brito
Andrade Filho, Francisco de Assis Oliveira
Carvalho, Carlos Gilvan Nunes de
author_role author
author2 Andrade Filho, Francisco de Assis Oliveira
Carvalho, Carlos Gilvan Nunes de
author2_role author
author
dc.contributor.author.fl_str_mv Freire, Ananda Soares de Brito
Andrade Filho, Francisco de Assis Oliveira
Carvalho, Carlos Gilvan Nunes de
dc.subject.por.fl_str_mv HIV
Creatinina
Tenofovir.
HIV
Creatinine
Tenofovir.
VIH
Creatinina
Tenofovir.
topic HIV
Creatinina
Tenofovir.
HIV
Creatinine
Tenofovir.
VIH
Creatinina
Tenofovir.
description This study aims to analyze the alteration in the renal function of PLHIV who used Tenofovir as part of their antiretroviral treatment. This was an observational epidemiological study, through a review of 86 records of PLHIV using Tenofovir, where a survey of data on creatinine values of patients was carried out. A data collection form covering demographic, clinical and laboratory data was used. The estimated Glomerular Filtration Rate was calculated by the CKD-EPI formula. With the results of this study, it was observed that so far, there are no medications free of adverse effects, but it was seen that in addition to monitoring the renal function of patients, it is necessary to prioritize the control of the patient's underlying diseases, as well as the maintenance of an undetectable viral load, a fact that was found in this study, when using TDF as ARVT.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/24502
10.33448/rsd-v11i1.24502
url https://rsdjournal.org/index.php/rsd/article/view/24502
identifier_str_mv 10.33448/rsd-v11i1.24502
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/24502/21616
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 1; e4911124502
Research, Society and Development; Vol. 11 Núm. 1; e4911124502
Research, Society and Development; v. 11 n. 1; e4911124502
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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