Clinical management of postpartum hemorrhage: an integrative review
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/23363 |
Resumo: | Introduction: Postpartum hemorrhage is the cause of approximately 25% of all deaths of pregnant women worldwide and is responsible for a large proportion of severe maternal morbidities. Thus, we aimed to evaluate and synthesize the latest publications on the clinical treatment of this event. Methodology: This is an integrative review conducted from January to June 2021, which aimed to answer the following guiding question: "What is the recent evidence available in the literature on the clinical treatment of postpartum hemorrhage? The search considered the last 5 years and resulted in 150 articles, of which 12 were selected due to eligibility criteria. Results: All articles were randomized clinical trials and written in English, published in international journals. Regarding the countries of performance, 4 studies were performed in two or more countries and the others were performed in 7 different countries. Discussion: Oxytocin infusion is considered the gold standard for the treatment of postpartum hemorrhage. However, when there is unavailability or contraindication to the use of this drug, data on recommendations for second-line therapies are lacking. In this sense, other drugs such as methylergometrine, tranexamic acid, misoprostol, among others, may become advantageous. Conclusion: Due to the impact that this hemorrhage has on maternal health, the importance of identifying secondary strategies for its control is evident, demonstrating the appropriate routes of administration, safety and effectiveness of the drugs. |
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Clinical management of postpartum hemorrhage: an integrative reviewManejo clínico de la hemorragia posparto: una revisión integradoraTratamento clínico da hemorragia pós-parto: uma revisão integrativaHemorrhagePostpartum HemorrhageTreatmentHemorragiaPospartoTratamiento.HemorragiaHemorragia pós-partoTratamento.Introduction: Postpartum hemorrhage is the cause of approximately 25% of all deaths of pregnant women worldwide and is responsible for a large proportion of severe maternal morbidities. Thus, we aimed to evaluate and synthesize the latest publications on the clinical treatment of this event. Methodology: This is an integrative review conducted from January to June 2021, which aimed to answer the following guiding question: "What is the recent evidence available in the literature on the clinical treatment of postpartum hemorrhage? The search considered the last 5 years and resulted in 150 articles, of which 12 were selected due to eligibility criteria. Results: All articles were randomized clinical trials and written in English, published in international journals. Regarding the countries of performance, 4 studies were performed in two or more countries and the others were performed in 7 different countries. Discussion: Oxytocin infusion is considered the gold standard for the treatment of postpartum hemorrhage. However, when there is unavailability or contraindication to the use of this drug, data on recommendations for second-line therapies are lacking. In this sense, other drugs such as methylergometrine, tranexamic acid, misoprostol, among others, may become advantageous. Conclusion: Due to the impact that this hemorrhage has on maternal health, the importance of identifying secondary strategies for its control is evident, demonstrating the appropriate routes of administration, safety and effectiveness of the drugs.Introducción: La hemorragia postparto es la causa de aproximadamente el 25% de todas las muertes de gestantes en el mundo y es responsable de gran parte de la morbilidad materna grave. Por lo tanto, el objetivo era evaluar y sintetizar las últimas publicaciones sobre el tratamiento clínico para este evento. Metodología: Se trata de una revisión integradora realizada en el período de enero a junio del año 2021, que tenía como objetivo responder a la siguiente pregunta norteamericana: "¿Cuáles son las evidencias recientes disponibles en la literatura sobre el tratamiento clínico de la hemorragia postparto?". La búsqueda tuvo en cuenta los últimos 5 años y dio como resultado 150 artículos, de los cuales se seleccionaron 12 debido a los criterios de elegibilidad. Resultados: Todos los artículos fueron ensayos clínicos aleatorios y rediseñados en lengua inglesa, siendo publicados en periódicos internacionales. En cuanto a los países de realización, 4 estudios se realizaron en dos o más países y los demás se realizaron en 7 países diferentes. Discusión: La infusión de oxitocina se considera el estándar de oro para el tratamiento de la hemorragia posparto. Sin embargo, cuando no hay disponibilidad o contraindicación para el uso de este fármaco, faltan datos sobre las recomendaciones para las terapias de segunda línea. En este sentido, otros fármacos como la metilergometrina, el ácido tranexámico, el misoprostol, entre otros, pueden resultar ventajosos. Conclusión: Debido al impacto que esta hemorragia tiene en la salud materna, es evidente la importancia de la identificación de estrategias secundarias para su control, demostrando las vías de administración adecuadas, la seguridad y la eficacia de los medicamentos.Introdução: A Hemorragia Pós-Parto é a causa de aproximadamente 25% de todas as mortes de gestantes no mundo e é responsável por grande parte das morbidades maternas graves. Assim, objetivou-se avaliar e sintetizar as últimas publicações acerca do tratamento clínico para este evento. Metodologia: Trata-se de uma revisão integrativa realizada no período de janeiro a junho do ano de 2021, que objetivou responder ao seguinte questionamento norteador: “Quais são as evidências recentes disponíveis na literatura acerca do tratamento clínico da hemorragia pós-parto?”. A busca considerou os últimos 5 anos e resultou em 150 artigos, dos quais 12 foram selecionados devido aos critérios de elegibilidade. Resultados: Todos os artigos foram ensaios clínicos randomizados e redigidos em língua inglesa, sendo publicados em periódicos internacionais. Em relação aos países de realização, 4 estudos foram realizados em dois ou mais países e os demais foram executados em 7 países distintos. Discussão: A infusão de ocitocina é considerada o padrão-ouro para o tratamento da hemorragia pós-parto. Contudo, quando há indisponibilidade ou contraindicação ao uso desse medicamento, faltam dados sobre as recomendações para as terapias de segunda linha. Nesse sentido, outros medicamentos como metilergometrina, ácido tranexâmico, misoprostol, entre outros, podem se tornar vantajosos. Conclusão: Devido ao impacto que esta hemorragia tem na saúde materna, é evidente a importância da identificação de estratégias secundárias para seu controle, demonstrando as vias de administração adequadas, segurança e efetividade dos medicamentos.Research, Society and Development2021-12-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2336310.33448/rsd-v10i16.23363Research, Society and Development; Vol. 10 No. 16; e84101623363Research, Society and Development; Vol. 10 Núm. 16; e84101623363Research, Society and Development; v. 10 n. 16; e841016233632525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/23363/21277Copyright (c) 2021 Antonio Paulo Nunes da Silva; Maria Eduarda da Silva Dias; Pollyana Rodrigues Diniz; Valda Lúcia Moreira Luna; George Alessandro Maranhão Conrado; Pauliana Valéria Machado Galvãohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Antonio Paulo Nunes da Dias, Maria Eduarda da Silva Diniz, Pollyana Rodrigues Luna, Valda Lúcia MoreiraConrado, George Alessandro Maranhão Galvão, Pauliana Valéria Machado2021-12-20T11:03:07Zoai:ojs.pkp.sfu.ca:article/23363Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:15.663511Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Clinical management of postpartum hemorrhage: an integrative review Manejo clínico de la hemorragia posparto: una revisión integradora Tratamento clínico da hemorragia pós-parto: uma revisão integrativa |
title |
Clinical management of postpartum hemorrhage: an integrative review |
spellingShingle |
Clinical management of postpartum hemorrhage: an integrative review Silva, Antonio Paulo Nunes da Hemorrhage Postpartum Hemorrhage Treatment Hemorragia Posparto Tratamiento. Hemorragia Hemorragia pós-parto Tratamento. |
title_short |
Clinical management of postpartum hemorrhage: an integrative review |
title_full |
Clinical management of postpartum hemorrhage: an integrative review |
title_fullStr |
Clinical management of postpartum hemorrhage: an integrative review |
title_full_unstemmed |
Clinical management of postpartum hemorrhage: an integrative review |
title_sort |
Clinical management of postpartum hemorrhage: an integrative review |
author |
Silva, Antonio Paulo Nunes da |
author_facet |
Silva, Antonio Paulo Nunes da Dias, Maria Eduarda da Silva Diniz, Pollyana Rodrigues Luna, Valda Lúcia Moreira Conrado, George Alessandro Maranhão Galvão, Pauliana Valéria Machado |
author_role |
author |
author2 |
Dias, Maria Eduarda da Silva Diniz, Pollyana Rodrigues Luna, Valda Lúcia Moreira Conrado, George Alessandro Maranhão Galvão, Pauliana Valéria Machado |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Silva, Antonio Paulo Nunes da Dias, Maria Eduarda da Silva Diniz, Pollyana Rodrigues Luna, Valda Lúcia Moreira Conrado, George Alessandro Maranhão Galvão, Pauliana Valéria Machado |
dc.subject.por.fl_str_mv |
Hemorrhage Postpartum Hemorrhage Treatment Hemorragia Posparto Tratamiento. Hemorragia Hemorragia pós-parto Tratamento. |
topic |
Hemorrhage Postpartum Hemorrhage Treatment Hemorragia Posparto Tratamiento. Hemorragia Hemorragia pós-parto Tratamento. |
description |
Introduction: Postpartum hemorrhage is the cause of approximately 25% of all deaths of pregnant women worldwide and is responsible for a large proportion of severe maternal morbidities. Thus, we aimed to evaluate and synthesize the latest publications on the clinical treatment of this event. Methodology: This is an integrative review conducted from January to June 2021, which aimed to answer the following guiding question: "What is the recent evidence available in the literature on the clinical treatment of postpartum hemorrhage? The search considered the last 5 years and resulted in 150 articles, of which 12 were selected due to eligibility criteria. Results: All articles were randomized clinical trials and written in English, published in international journals. Regarding the countries of performance, 4 studies were performed in two or more countries and the others were performed in 7 different countries. Discussion: Oxytocin infusion is considered the gold standard for the treatment of postpartum hemorrhage. However, when there is unavailability or contraindication to the use of this drug, data on recommendations for second-line therapies are lacking. In this sense, other drugs such as methylergometrine, tranexamic acid, misoprostol, among others, may become advantageous. Conclusion: Due to the impact that this hemorrhage has on maternal health, the importance of identifying secondary strategies for its control is evident, demonstrating the appropriate routes of administration, safety and effectiveness of the drugs. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-12-19 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/23363 10.33448/rsd-v10i16.23363 |
url |
https://rsdjournal.org/index.php/rsd/article/view/23363 |
identifier_str_mv |
10.33448/rsd-v10i16.23363 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/23363/21277 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 16; e84101623363 Research, Society and Development; Vol. 10 Núm. 16; e84101623363 Research, Society and Development; v. 10 n. 16; e84101623363 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052697391661056 |