Clinical management of postpartum hemorrhage: an integrative review

Detalhes bibliográficos
Autor(a) principal: Silva, Antonio Paulo Nunes da
Data de Publicação: 2021
Outros Autores: Dias, Maria Eduarda da Silva, Diniz, Pollyana Rodrigues, Luna, Valda Lúcia Moreira, Conrado, George Alessandro Maranhão, Galvão, Pauliana Valéria Machado
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/23363
Resumo: Introduction: Postpartum hemorrhage is the cause of approximately 25% of all deaths of pregnant women worldwide and is responsible for a large proportion of severe maternal morbidities. Thus, we aimed to evaluate and synthesize the latest publications on the clinical treatment of this event. Methodology: This is an integrative review conducted from January to June 2021, which aimed to answer the following guiding question: "What is the recent evidence available in the literature on the clinical treatment of postpartum hemorrhage? The search considered the last 5 years and resulted in 150 articles, of which 12 were selected due to eligibility criteria. Results: All articles were randomized clinical trials and written in English, published in international journals. Regarding the countries of performance, 4 studies were performed in two or more countries and the others were performed in 7 different countries. Discussion: Oxytocin infusion is considered the gold standard for the treatment of postpartum hemorrhage. However, when there is unavailability or contraindication to the use of this drug, data on recommendations for second-line therapies are lacking. In this sense, other drugs such as methylergometrine, tranexamic acid, misoprostol, among others, may become advantageous. Conclusion: Due to the impact that this hemorrhage has on maternal health, the importance of identifying secondary strategies for its control is evident, demonstrating the appropriate routes of administration, safety and effectiveness of the drugs.
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spelling Clinical management of postpartum hemorrhage: an integrative reviewManejo clínico de la hemorragia posparto: una revisión integradoraTratamento clínico da hemorragia pós-parto: uma revisão integrativaHemorrhagePostpartum HemorrhageTreatmentHemorragiaPospartoTratamiento.HemorragiaHemorragia pós-partoTratamento.Introduction: Postpartum hemorrhage is the cause of approximately 25% of all deaths of pregnant women worldwide and is responsible for a large proportion of severe maternal morbidities. Thus, we aimed to evaluate and synthesize the latest publications on the clinical treatment of this event. Methodology: This is an integrative review conducted from January to June 2021, which aimed to answer the following guiding question: "What is the recent evidence available in the literature on the clinical treatment of postpartum hemorrhage? The search considered the last 5 years and resulted in 150 articles, of which 12 were selected due to eligibility criteria. Results: All articles were randomized clinical trials and written in English, published in international journals. Regarding the countries of performance, 4 studies were performed in two or more countries and the others were performed in 7 different countries. Discussion: Oxytocin infusion is considered the gold standard for the treatment of postpartum hemorrhage. However, when there is unavailability or contraindication to the use of this drug, data on recommendations for second-line therapies are lacking. In this sense, other drugs such as methylergometrine, tranexamic acid, misoprostol, among others, may become advantageous. Conclusion: Due to the impact that this hemorrhage has on maternal health, the importance of identifying secondary strategies for its control is evident, demonstrating the appropriate routes of administration, safety and effectiveness of the drugs.Introducción: La hemorragia postparto es la causa de aproximadamente el 25% de todas las muertes de gestantes en el mundo y es responsable de gran parte de la morbilidad materna grave. Por lo tanto, el objetivo era evaluar y sintetizar las últimas publicaciones sobre el tratamiento clínico para este evento. Metodología: Se trata de una revisión integradora realizada en el período de enero a junio del año 2021, que tenía como objetivo responder a la siguiente pregunta norteamericana: "¿Cuáles son las evidencias recientes disponibles en la literatura sobre el tratamiento clínico de la hemorragia postparto?". La búsqueda tuvo en cuenta los últimos 5 años y dio como resultado 150 artículos, de los cuales se seleccionaron 12 debido a los criterios de elegibilidad. Resultados: Todos los artículos fueron ensayos clínicos aleatorios y rediseñados en lengua inglesa, siendo publicados en periódicos internacionales. En cuanto a los países de realización, 4 estudios se realizaron en dos o más países y los demás se realizaron en 7 países diferentes. Discusión: La infusión de oxitocina se considera el estándar de oro para el tratamiento de la hemorragia posparto. Sin embargo, cuando no hay disponibilidad o contraindicación para el uso de este fármaco, faltan datos sobre las recomendaciones para las terapias de segunda línea. En este sentido, otros fármacos como la metilergometrina, el ácido tranexámico, el misoprostol, entre otros, pueden resultar ventajosos. Conclusión: Debido al impacto que esta hemorragia tiene en la salud materna, es evidente la importancia de la identificación de estrategias secundarias para su control, demostrando las vías de administración adecuadas, la seguridad y la eficacia de los medicamentos.Introdução: A Hemorragia Pós-Parto é a causa de aproximadamente 25% de todas as mortes de gestantes no mundo e é responsável por grande parte das morbidades maternas graves. Assim, objetivou-se avaliar e sintetizar as últimas publicações acerca do tratamento clínico para este evento. Metodologia: Trata-se de uma revisão integrativa realizada no período de janeiro a junho do ano de 2021, que objetivou responder ao seguinte questionamento norteador: “Quais são as evidências recentes disponíveis na literatura acerca do tratamento clínico da hemorragia pós-parto?”. A busca considerou os últimos 5 anos e resultou em 150 artigos, dos quais 12 foram selecionados devido aos critérios de elegibilidade. Resultados: Todos os artigos foram ensaios clínicos randomizados e redigidos em língua inglesa, sendo publicados em periódicos internacionais. Em relação aos países de realização, 4 estudos foram realizados em dois ou mais países e os demais foram executados em 7 países distintos. Discussão: A infusão de ocitocina é considerada o padrão-ouro para o tratamento da hemorragia pós-parto. Contudo, quando há indisponibilidade ou contraindicação ao uso desse medicamento, faltam dados sobre as recomendações para as terapias de segunda linha. Nesse sentido, outros medicamentos como metilergometrina, ácido tranexâmico, misoprostol, entre outros, podem se tornar vantajosos. Conclusão: Devido ao impacto que esta hemorragia tem na saúde materna, é evidente a importância da identificação de estratégias secundárias para seu controle, demonstrando as vias de administração adequadas, segurança e efetividade dos medicamentos.Research, Society and Development2021-12-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2336310.33448/rsd-v10i16.23363Research, Society and Development; Vol. 10 No. 16; e84101623363Research, Society and Development; Vol. 10 Núm. 16; e84101623363Research, Society and Development; v. 10 n. 16; e841016233632525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/23363/21277Copyright (c) 2021 Antonio Paulo Nunes da Silva; Maria Eduarda da Silva Dias; Pollyana Rodrigues Diniz; Valda Lúcia Moreira Luna; George Alessandro Maranhão Conrado; Pauliana Valéria Machado Galvãohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Antonio Paulo Nunes da Dias, Maria Eduarda da Silva Diniz, Pollyana Rodrigues Luna, Valda Lúcia MoreiraConrado, George Alessandro Maranhão Galvão, Pauliana Valéria Machado2021-12-20T11:03:07Zoai:ojs.pkp.sfu.ca:article/23363Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:15.663511Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Clinical management of postpartum hemorrhage: an integrative review
Manejo clínico de la hemorragia posparto: una revisión integradora
Tratamento clínico da hemorragia pós-parto: uma revisão integrativa
title Clinical management of postpartum hemorrhage: an integrative review
spellingShingle Clinical management of postpartum hemorrhage: an integrative review
Silva, Antonio Paulo Nunes da
Hemorrhage
Postpartum Hemorrhage
Treatment
Hemorragia
Posparto
Tratamiento.
Hemorragia
Hemorragia pós-parto
Tratamento.
title_short Clinical management of postpartum hemorrhage: an integrative review
title_full Clinical management of postpartum hemorrhage: an integrative review
title_fullStr Clinical management of postpartum hemorrhage: an integrative review
title_full_unstemmed Clinical management of postpartum hemorrhage: an integrative review
title_sort Clinical management of postpartum hemorrhage: an integrative review
author Silva, Antonio Paulo Nunes da
author_facet Silva, Antonio Paulo Nunes da
Dias, Maria Eduarda da Silva
Diniz, Pollyana Rodrigues
Luna, Valda Lúcia Moreira
Conrado, George Alessandro Maranhão
Galvão, Pauliana Valéria Machado
author_role author
author2 Dias, Maria Eduarda da Silva
Diniz, Pollyana Rodrigues
Luna, Valda Lúcia Moreira
Conrado, George Alessandro Maranhão
Galvão, Pauliana Valéria Machado
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Antonio Paulo Nunes da
Dias, Maria Eduarda da Silva
Diniz, Pollyana Rodrigues
Luna, Valda Lúcia Moreira
Conrado, George Alessandro Maranhão
Galvão, Pauliana Valéria Machado
dc.subject.por.fl_str_mv Hemorrhage
Postpartum Hemorrhage
Treatment
Hemorragia
Posparto
Tratamiento.
Hemorragia
Hemorragia pós-parto
Tratamento.
topic Hemorrhage
Postpartum Hemorrhage
Treatment
Hemorragia
Posparto
Tratamiento.
Hemorragia
Hemorragia pós-parto
Tratamento.
description Introduction: Postpartum hemorrhage is the cause of approximately 25% of all deaths of pregnant women worldwide and is responsible for a large proportion of severe maternal morbidities. Thus, we aimed to evaluate and synthesize the latest publications on the clinical treatment of this event. Methodology: This is an integrative review conducted from January to June 2021, which aimed to answer the following guiding question: "What is the recent evidence available in the literature on the clinical treatment of postpartum hemorrhage? The search considered the last 5 years and resulted in 150 articles, of which 12 were selected due to eligibility criteria. Results: All articles were randomized clinical trials and written in English, published in international journals. Regarding the countries of performance, 4 studies were performed in two or more countries and the others were performed in 7 different countries. Discussion: Oxytocin infusion is considered the gold standard for the treatment of postpartum hemorrhage. However, when there is unavailability or contraindication to the use of this drug, data on recommendations for second-line therapies are lacking. In this sense, other drugs such as methylergometrine, tranexamic acid, misoprostol, among others, may become advantageous. Conclusion: Due to the impact that this hemorrhage has on maternal health, the importance of identifying secondary strategies for its control is evident, demonstrating the appropriate routes of administration, safety and effectiveness of the drugs.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-19
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/23363
10.33448/rsd-v10i16.23363
url https://rsdjournal.org/index.php/rsd/article/view/23363
identifier_str_mv 10.33448/rsd-v10i16.23363
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/23363/21277
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 16; e84101623363
Research, Society and Development; Vol. 10 Núm. 16; e84101623363
Research, Society and Development; v. 10 n. 16; e84101623363
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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