The effects of using omega 3 in the treatment of patients with Alzheimer
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/22654 |
Resumo: | Introduction: The aging process is a risk factor for neurological diseases such as Alzheimer's disease. Omega 3 is a fatty acid present in neuronal membranes and plays a fundamental role in the metabolism of nervous tissue. Objective: to describe the effects of using omega 3 in the treatment of patients with Alzheimer's Disease. Method: this is an integrative review developed in LILACS, MEDLINE AND EMBASE databases using the descriptors: Alzheimer Disease, Omega-3 Fatty Acids, Therapeutics and Disease Prevention. 483 articles were found, but 476 did not meet the eligibility criteria and were excluded. A comparative analysis of the data extracted from the articles selected for the final sample was carried out. Results: The sample consisted of seven articles. There was a prevalence of the use of capsules containing 800 mg of docosahexaenoic acid and 225 mg of eicosapentaenoic acid. Fatty acids have been shown to have the potential to reduce the accumulation of beta amyloid proteins in cortical regions of the brain or even prevent formation, in addition to increasing cortical thickness. Conclusion: Supplementation with omega 3 has beneficial effects in the treatment of patients with Alzheimer's, as it has neuroprotective characteristics in combating morphophysiological changes that normally occur in the pathological environment. |
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The effects of using omega 3 in the treatment of patients with AlzheimerLos efectos del uso de omega 3 en el tratamiento de pacientes con AlzheimerOs efeitos do uso do ômega 3 no tratamento de pacientes com AlzheimerAlzheimer DiseaseOmega-3 Fatty AcidsTherapeutics.Enfermedad de AlzheimerÁcidos Grasos Omega-3Terapéutica.Doença de AlzheierÁcidos Graxos Ômega-3Terapêutica.Introduction: The aging process is a risk factor for neurological diseases such as Alzheimer's disease. Omega 3 is a fatty acid present in neuronal membranes and plays a fundamental role in the metabolism of nervous tissue. Objective: to describe the effects of using omega 3 in the treatment of patients with Alzheimer's Disease. Method: this is an integrative review developed in LILACS, MEDLINE AND EMBASE databases using the descriptors: Alzheimer Disease, Omega-3 Fatty Acids, Therapeutics and Disease Prevention. 483 articles were found, but 476 did not meet the eligibility criteria and were excluded. A comparative analysis of the data extracted from the articles selected for the final sample was carried out. Results: The sample consisted of seven articles. There was a prevalence of the use of capsules containing 800 mg of docosahexaenoic acid and 225 mg of eicosapentaenoic acid. Fatty acids have been shown to have the potential to reduce the accumulation of beta amyloid proteins in cortical regions of the brain or even prevent formation, in addition to increasing cortical thickness. Conclusion: Supplementation with omega 3 has beneficial effects in the treatment of patients with Alzheimer's, as it has neuroprotective characteristics in combating morphophysiological changes that normally occur in the pathological environment.Introducción: El proceso de envejecimiento es un factor de riesgo de enfermedades neurológicas como la enfermedad de Alzheimer. El Omega 3 es un ácido graso presente en las membranas neuronales y juega un papel fundamental en el metabolismo del tejido nervioso. Objetivo: describir los efectos del uso de omega 3 en el tratamiento de pacientes con enfermedad de Alzheimer. Método: se trata de una revisión integradora desarrollada en las bases de datos LILACS, MEDLINE Y EMBASE utilizando los descriptores: Enfermedad de Alzheimer, Ácidos Grasos Omega-3, Terapéutica y Prevención de Enfermedades. Se encontraron 483 artículos, pero 476 no cumplieron con los criterios de elegibilidad y fueron excluidos. Se realizó un análisis comparativo de los datos extraídos de los artículos seleccionados para la muestra final. Resultados: La muestra estuvo conformada por siete artículos. Prevaleció el uso de cápsulas que contenían 800 mg de ácido docosahexaenoico y 225 mg de ácido eicosapentaenoico. Se ha demostrado que los ácidos grasos tienen el potencial de reducir la acumulación de proteínas beta amiloides en las regiones corticales del cerebro o incluso prevenir la formación, además de aumentar el grosor cortical. Conclusión: La suplementación con omega 3 tiene efectos beneficiosos en el tratamiento de pacientes con Alzheimer, ya que posee características neuroprotectoras para combatir los cambios morfofisiológicos que normalmente ocurren en el entorno patológico.Introdução: O processo de envelhecimento é um fator de risco para doenças neurológicas, como a doença de Alzheimer. O ômega 3 é um ácido graxo presente nas membranas neuronais e desempenha um papel fundamental no metabolismo do tecido nervoso. Objetivo: descrever os efeitos do uso do ômega 3 no tratamento de pacientes com Doença de Alzheimer. Método: trata-se de uma revisão integrativa desenvolvida nas bases de dados da LILACS, MEDLINE E EMBASE por meio dos descritores: Alzheimer Disease, Omega-3 Fatty Acids, Therapeutics e Disease Prevention . Foram localizados 483 artigos, mas 476 não atenderam aos critérios de elegibilidade e foram excluídos. Realizou-se uma análise comparativa dos dados extraídos dos artigos selecionados para a amostra final. Resultados: A amostra foi composta por sete artigos. Houve prevalência do uso de cápsulas contendo 800 mg de ácido docosa-hexaenóico e 225 mg de ácido eicosapentaenóico. Os ácidos graxos demonstraram ter potencial de reduzir o acúmulo de proteínas beta amilóide em regiões corticais do cérebro ou até a prevenção de formação, além de aumentar a espessura cortical. Conclusão: A suplementação com ômega 3 possui efeitos benéficos no tratamento de pacientes com alzheimer ao possuir características neuroprotetoras no combate a alterações morfofisiológicas que normalmente ocorrem no ambiente patológico.Research, Society and Development2021-11-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2265410.33448/rsd-v10i15.22654Research, Society and Development; Vol. 10 No. 15; e239101522654Research, Society and Development; Vol. 10 Núm. 15; e239101522654Research, Society and Development; v. 10 n. 15; e2391015226542525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/22654/20032Copyright (c) 2021 Poliane Josefa Costa; Maria Micaele da Silva; João Paulo Guedeshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCosta, Poliane Josefa Silva, Maria Micaele da Guedes, João Paulo 2021-12-06T10:13:53Zoai:ojs.pkp.sfu.ca:article/22654Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:41:45.718196Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
The effects of using omega 3 in the treatment of patients with Alzheimer Los efectos del uso de omega 3 en el tratamiento de pacientes con Alzheimer Os efeitos do uso do ômega 3 no tratamento de pacientes com Alzheimer |
title |
The effects of using omega 3 in the treatment of patients with Alzheimer |
spellingShingle |
The effects of using omega 3 in the treatment of patients with Alzheimer Costa, Poliane Josefa Alzheimer Disease Omega-3 Fatty Acids Therapeutics. Enfermedad de Alzheimer Ácidos Grasos Omega-3 Terapéutica. Doença de Alzheier Ácidos Graxos Ômega-3 Terapêutica. |
title_short |
The effects of using omega 3 in the treatment of patients with Alzheimer |
title_full |
The effects of using omega 3 in the treatment of patients with Alzheimer |
title_fullStr |
The effects of using omega 3 in the treatment of patients with Alzheimer |
title_full_unstemmed |
The effects of using omega 3 in the treatment of patients with Alzheimer |
title_sort |
The effects of using omega 3 in the treatment of patients with Alzheimer |
author |
Costa, Poliane Josefa |
author_facet |
Costa, Poliane Josefa Silva, Maria Micaele da Guedes, João Paulo |
author_role |
author |
author2 |
Silva, Maria Micaele da Guedes, João Paulo |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Costa, Poliane Josefa Silva, Maria Micaele da Guedes, João Paulo |
dc.subject.por.fl_str_mv |
Alzheimer Disease Omega-3 Fatty Acids Therapeutics. Enfermedad de Alzheimer Ácidos Grasos Omega-3 Terapéutica. Doença de Alzheier Ácidos Graxos Ômega-3 Terapêutica. |
topic |
Alzheimer Disease Omega-3 Fatty Acids Therapeutics. Enfermedad de Alzheimer Ácidos Grasos Omega-3 Terapéutica. Doença de Alzheier Ácidos Graxos Ômega-3 Terapêutica. |
description |
Introduction: The aging process is a risk factor for neurological diseases such as Alzheimer's disease. Omega 3 is a fatty acid present in neuronal membranes and plays a fundamental role in the metabolism of nervous tissue. Objective: to describe the effects of using omega 3 in the treatment of patients with Alzheimer's Disease. Method: this is an integrative review developed in LILACS, MEDLINE AND EMBASE databases using the descriptors: Alzheimer Disease, Omega-3 Fatty Acids, Therapeutics and Disease Prevention. 483 articles were found, but 476 did not meet the eligibility criteria and were excluded. A comparative analysis of the data extracted from the articles selected for the final sample was carried out. Results: The sample consisted of seven articles. There was a prevalence of the use of capsules containing 800 mg of docosahexaenoic acid and 225 mg of eicosapentaenoic acid. Fatty acids have been shown to have the potential to reduce the accumulation of beta amyloid proteins in cortical regions of the brain or even prevent formation, in addition to increasing cortical thickness. Conclusion: Supplementation with omega 3 has beneficial effects in the treatment of patients with Alzheimer's, as it has neuroprotective characteristics in combating morphophysiological changes that normally occur in the pathological environment. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-11-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/22654 10.33448/rsd-v10i15.22654 |
url |
https://rsdjournal.org/index.php/rsd/article/view/22654 |
identifier_str_mv |
10.33448/rsd-v10i15.22654 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/22654/20032 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 Poliane Josefa Costa; Maria Micaele da Silva; João Paulo Guedes https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2021 Poliane Josefa Costa; Maria Micaele da Silva; João Paulo Guedes https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 15; e239101522654 Research, Society and Development; Vol. 10 Núm. 15; e239101522654 Research, Society and Development; v. 10 n. 15; e239101522654 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052695733862400 |