Secondary catatonia to systemic lupus erythematosus: Systematic review

Detalhes bibliográficos
Autor(a) principal: Figueiredo, João César Queiroga de
Data de Publicação: 2022
Outros Autores: Aquino, Rachel de Souza, Figueiredo, Evânia Claudino Queiroga de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/33412
Resumo: Systemic Lupus Erythematosus (SLE) is an autoimmune disease that is known to be associated with neuropsychiatric manifestations with a prevalence of 17 to 75% in patients with the disease. Catatonia has been described in the clinical spectrum of neuropsychiatric manifestations (NPM) of SLE. The aim of this study was to characterize, through a systematic review, the clinical manifestations and treatment of catatonia induced by Systemic Lupus Erythematosus (SLE). A systematic review of a case report and series was carried out using the descriptors “Systemic Lupus Erythematosus” and “Catatonia”, from 1977 to 2021, in the published Medline©, PubMed©, Lilacs©, Scielo© and EMBASE© databases. in Spanish, French, English and Portuguese. Of a total of 50 patients analyzed in the selected studies, about 54% were aged between 18 and 35 years, with a total prevalence in females, 90%. It was evidenced that the clinical picture is quite varied, with a predominance of mutism (75%), immobility/stupor (55%), rigidity (40%) and waxy flexibility (40%). 46% of patients had central nervous system alterations detected by brain magnetic resonance imaging, cranial computed tomography, electroencephalogram or lumbar puncture. Regarding the treatment proposed to each patient, with a description of improvement, the use of benzodiazepines, electroconvulsive therapy, glucocorticoids and immunosuppressants are responsible for almost all the resolution responses. It is concluded that psychiatric disorders are not well described in SLE. This study highlights the importance of diagnosing and treating psychiatric disorders, especially catatonic syndrome. SLE should therefore be included in the differential diagnosis of patients presenting with catatonic syndrome.
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spelling Secondary catatonia to systemic lupus erythematosus: Systematic reviewCatatonia secundaria a lupus eritematoso sistémico: Revisión sistemática Catatonia secundária ao lúpus eritematoso sistêmico: Revisão sistemáticaCatatoniaSystemic lupus erythematosusNeuropsychiatry.CatatoníaLupus eritematoso sistémicoNeurosiquiatría.CatatoniaLúpus eritematoso sistêmicoNeuropsiquiatria.Systemic Lupus Erythematosus (SLE) is an autoimmune disease that is known to be associated with neuropsychiatric manifestations with a prevalence of 17 to 75% in patients with the disease. Catatonia has been described in the clinical spectrum of neuropsychiatric manifestations (NPM) of SLE. The aim of this study was to characterize, through a systematic review, the clinical manifestations and treatment of catatonia induced by Systemic Lupus Erythematosus (SLE). A systematic review of a case report and series was carried out using the descriptors “Systemic Lupus Erythematosus” and “Catatonia”, from 1977 to 2021, in the published Medline©, PubMed©, Lilacs©, Scielo© and EMBASE© databases. in Spanish, French, English and Portuguese. Of a total of 50 patients analyzed in the selected studies, about 54% were aged between 18 and 35 years, with a total prevalence in females, 90%. It was evidenced that the clinical picture is quite varied, with a predominance of mutism (75%), immobility/stupor (55%), rigidity (40%) and waxy flexibility (40%). 46% of patients had central nervous system alterations detected by brain magnetic resonance imaging, cranial computed tomography, electroencephalogram or lumbar puncture. Regarding the treatment proposed to each patient, with a description of improvement, the use of benzodiazepines, electroconvulsive therapy, glucocorticoids and immunosuppressants are responsible for almost all the resolution responses. It is concluded that psychiatric disorders are not well described in SLE. This study highlights the importance of diagnosing and treating psychiatric disorders, especially catatonic syndrome. SLE should therefore be included in the differential diagnosis of patients presenting with catatonic syndrome.El lupus eritematoso sistémico (LES) es una enfermedad autoinmune que se sabe que está asociada con manifestaciones neuropsiquiátricas con una prevalencia del 17 al 75% en pacientes con la enfermedad. La catatonia se ha descrito en el espectro clínico de las manifestaciones neuropsiquiátricas (NPM) del LES. El objetivo de este estudio fue caracterizar, a través de una revisión sistemática, las manifestaciones clínicas y el tratamiento de la catatonia inducida por Lupus Eritematoso Sistémico (LES). Se realizó una revisión sistemática de un reporte de caso y serie utilizando los descriptores “Systemic Lupus Erythematosus” y “Catatonia”, desde 1977 hasta 2021, en las bases de datos publicadas Medline©, PubMed©, Lilacs©, Scielo© y EMBASE©. Español, francés, inglés y portugués. De un total de 50 pacientes analizados en los estudios seleccionados, cerca del 54% tenían entre 18 y 35 años, con un predominio total en el sexo femenino, del 90%. Se evidenció que el cuadro clínico es bastante variado, con predominio de mutismo (75%), inmovilidad/estupor (55%), rigidez (40%) y flexibilidad cérea (40%). Al 46% de los pacientes se les detectaron alteraciones del sistema nervioso central mediante resonancia magnética cerebral, tomografía computarizada craneal, electroencefalograma o punción lumbar. En cuanto al tratamiento propuesto a cada paciente, con descripción de mejoría, el uso de benzodiazepinas, terapia electroconvulsiva, glucocorticoides e inmunosupresores son los responsables de casi todas las respuestas de resolución. Se concluye que los trastornos psiquiátricos no están bien descritos en el LES. Este estudio destaca la importancia del diagnóstico y tratamiento de los trastornos psiquiátricos, especialmente el síndrome catatónico. Por lo tanto, el LES debe incluirse en el diagnóstico diferencial de los pacientes que presentan el síndrome catatónico.Lúpus Eritematoso Sistêmico (LES) é uma doença autoimune que é conhecido por estar associado a manifestações neuropsiquiátricas com uma prevalência de 17 a 75% nos portadores da doença. A catatonia tem sido descrita no espectro clínico das manifestações neuropsiquiátricas (MNP) do LES. O objetivo desse estudo foi caracterizar, por meio de uma revisão sistemática, as manifestações clínicas e a terapêutica da catatonia induzida por Lúpus Eritematoso Sistêmico (LES). Foi realizado uma revisão sistemática de relato e série de casos utilizando os descritores “Systemic Lupus Erythematosus” e “Catatonia”, no período de 1977 a 2021, nas bases de dados Medline©, PubMed©, Lilacs©, Scielo© e EMBASE© publicados em Espanhol, Francês, Inglês e Português. De um total de 50 pacientes analisados nos estudos selecionados, cerca de 54% tinham idade entre 18 e 35 anos, com prevalência total no sexo feminino, 90%. Evidenciou-se que o quadro clínico é bem variado com predominância de mutismo (75%), imobilidade/estupor (55%), rigidez (40%) e flexibilidade cérea (40%). 46% dos pacientes apresentaram alterações do sistema nervoso central detectado através da ressonância magnética de cérebro, tomografia computadorizada de crânio, eletroencefalograma ou punção lombar. Em relação ao tratamento proposto a cada paciente, com descrição de melhora, tem-se o uso de benzodiazepínicos, eletroconvulsoterapia, glicocorticoides e imunossupressores como responsáveis por quase todas as respostas de resolutividade. Conclui-se que os transtornos psiquiátricos não são bem descritos no LES. Este estudo evidencia a importância do diagnóstico e tratamento de transtornos psiquiátricos, especialmente a síndrome catatônica. LES deve, portanto, ser incluído no diagnóstico diferencial de pacientes apresentando a síndrome catatônica.  Research, Society and Development2022-08-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3341210.33448/rsd-v11i11.33412Research, Society and Development; Vol. 11 No. 11; e150111133412Research, Society and Development; Vol. 11 Núm. 11; e150111133412Research, Society and Development; v. 11 n. 11; e1501111334122525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/33412/28285Copyright (c) 2022 João César Queiroga de Figueiredo; Rachel de Souza Aquino; Evânia Claudino Queiroga de Figueiredohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFigueiredo, João César Queiroga de Aquino, Rachel de Souza Figueiredo, Evânia Claudino Queiroga de 2022-09-05T13:24:46Zoai:ojs.pkp.sfu.ca:article/33412Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:49:04.203183Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Secondary catatonia to systemic lupus erythematosus: Systematic review
Catatonia secundaria a lupus eritematoso sistémico: Revisión sistemática
Catatonia secundária ao lúpus eritematoso sistêmico: Revisão sistemática
title Secondary catatonia to systemic lupus erythematosus: Systematic review
spellingShingle Secondary catatonia to systemic lupus erythematosus: Systematic review
Figueiredo, João César Queiroga de
Catatonia
Systemic lupus erythematosus
Neuropsychiatry.
Catatonía
Lupus eritematoso sistémico
Neurosiquiatría.
Catatonia
Lúpus eritematoso sistêmico
Neuropsiquiatria.
title_short Secondary catatonia to systemic lupus erythematosus: Systematic review
title_full Secondary catatonia to systemic lupus erythematosus: Systematic review
title_fullStr Secondary catatonia to systemic lupus erythematosus: Systematic review
title_full_unstemmed Secondary catatonia to systemic lupus erythematosus: Systematic review
title_sort Secondary catatonia to systemic lupus erythematosus: Systematic review
author Figueiredo, João César Queiroga de
author_facet Figueiredo, João César Queiroga de
Aquino, Rachel de Souza
Figueiredo, Evânia Claudino Queiroga de
author_role author
author2 Aquino, Rachel de Souza
Figueiredo, Evânia Claudino Queiroga de
author2_role author
author
dc.contributor.author.fl_str_mv Figueiredo, João César Queiroga de
Aquino, Rachel de Souza
Figueiredo, Evânia Claudino Queiroga de
dc.subject.por.fl_str_mv Catatonia
Systemic lupus erythematosus
Neuropsychiatry.
Catatonía
Lupus eritematoso sistémico
Neurosiquiatría.
Catatonia
Lúpus eritematoso sistêmico
Neuropsiquiatria.
topic Catatonia
Systemic lupus erythematosus
Neuropsychiatry.
Catatonía
Lupus eritematoso sistémico
Neurosiquiatría.
Catatonia
Lúpus eritematoso sistêmico
Neuropsiquiatria.
description Systemic Lupus Erythematosus (SLE) is an autoimmune disease that is known to be associated with neuropsychiatric manifestations with a prevalence of 17 to 75% in patients with the disease. Catatonia has been described in the clinical spectrum of neuropsychiatric manifestations (NPM) of SLE. The aim of this study was to characterize, through a systematic review, the clinical manifestations and treatment of catatonia induced by Systemic Lupus Erythematosus (SLE). A systematic review of a case report and series was carried out using the descriptors “Systemic Lupus Erythematosus” and “Catatonia”, from 1977 to 2021, in the published Medline©, PubMed©, Lilacs©, Scielo© and EMBASE© databases. in Spanish, French, English and Portuguese. Of a total of 50 patients analyzed in the selected studies, about 54% were aged between 18 and 35 years, with a total prevalence in females, 90%. It was evidenced that the clinical picture is quite varied, with a predominance of mutism (75%), immobility/stupor (55%), rigidity (40%) and waxy flexibility (40%). 46% of patients had central nervous system alterations detected by brain magnetic resonance imaging, cranial computed tomography, electroencephalogram or lumbar puncture. Regarding the treatment proposed to each patient, with a description of improvement, the use of benzodiazepines, electroconvulsive therapy, glucocorticoids and immunosuppressants are responsible for almost all the resolution responses. It is concluded that psychiatric disorders are not well described in SLE. This study highlights the importance of diagnosing and treating psychiatric disorders, especially catatonic syndrome. SLE should therefore be included in the differential diagnosis of patients presenting with catatonic syndrome.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-18
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33412
10.33448/rsd-v11i11.33412
url https://rsdjournal.org/index.php/rsd/article/view/33412
identifier_str_mv 10.33448/rsd-v11i11.33412
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33412/28285
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 11; e150111133412
Research, Society and Development; Vol. 11 Núm. 11; e150111133412
Research, Society and Development; v. 11 n. 11; e150111133412
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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