The indiscriminate and off label use of Ritalin
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/19108 |
Resumo: | Methylphenidate hydrochloride [(dl-treo-metil-2-fenil-2- (2-piperidil) acetato], known as Ritalin, is a psychotropic drug commonly used by people with Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy for its treatment. As it is a drug that acts on the nervous system by releasing norepinephrine and dopamine in the synaptic clefts, causing an excitation in postsynaptic receptors and altering the user's cognitive functions, the off label use to improve cognitive performance is becoming more and more common. This type of medication must be used rationally, as well as any other medication, as they can cause adverse effects and dependence. In view of the above, this study aimed to evaluate, through the literature, the correct way to use methylphenidate, the indiscriminate use, off label and the health problems that prolonged use can trigger in the user, as well as the importance of pharmaceutical care for effective treatment with methylphenidate. For this, an integrative literature review was carried out and the articles for this review were collected in the following search portals: SciELO, BVS and Lilacs. After collection, 21 studies were selected to compose the results. It was possible to notice that the indiscriminate use of methylphenidate hydrochloride has been carried out frequently by many people, especially by students, which can lead to serious complications and the appearance of serious adverse effects, especially cardiovascular events such as tachycardia and hypertension, psychiatric disorders such as depression, psychosis and chemical dependency, as well as the neurological system such as dyskinesia, involuntary muscle contractions and spasms, among others. |
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The indiscriminate and off label use of RitalinEl uso indiscriminado y no autorizado de RitalinO uso indiscriminado e off label da RitalinaOff labelRational useRitalinMethylphenidate.Off labelUso racionalRitalinMetilfenidato.Off labelUso racionalRitalinaMetilfenidato.Methylphenidate hydrochloride [(dl-treo-metil-2-fenil-2- (2-piperidil) acetato], known as Ritalin, is a psychotropic drug commonly used by people with Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy for its treatment. As it is a drug that acts on the nervous system by releasing norepinephrine and dopamine in the synaptic clefts, causing an excitation in postsynaptic receptors and altering the user's cognitive functions, the off label use to improve cognitive performance is becoming more and more common. This type of medication must be used rationally, as well as any other medication, as they can cause adverse effects and dependence. In view of the above, this study aimed to evaluate, through the literature, the correct way to use methylphenidate, the indiscriminate use, off label and the health problems that prolonged use can trigger in the user, as well as the importance of pharmaceutical care for effective treatment with methylphenidate. For this, an integrative literature review was carried out and the articles for this review were collected in the following search portals: SciELO, BVS and Lilacs. After collection, 21 studies were selected to compose the results. It was possible to notice that the indiscriminate use of methylphenidate hydrochloride has been carried out frequently by many people, especially by students, which can lead to serious complications and the appearance of serious adverse effects, especially cardiovascular events such as tachycardia and hypertension, psychiatric disorders such as depression, psychosis and chemical dependency, as well as the neurological system such as dyskinesia, involuntary muscle contractions and spasms, among others.El clorhidrato de metilfenidato [(dl-treo-metil-2-fenil-2- (2-piperidil) acetato], conocido como Ritalin, es un fármaco psicotrópico comúnmente utilizado por personas con trastorno por déficit de atención con hiperactividad (TDAH) y narcolepsia para su tratamiento. Al ser un fármaco que actúa sobre el sistema nervioso liberando noradrenalina y dopamina en las hendiduras sinápticas, provocando una excitación en los receptores postsinápticos y alterando las funciones cognitivas del usuario, el uso off label para mejorar el rendimiento cognitivo es cada vez más común. Este tipo de medicación debe utilizarse de forma racional, así como cualquier otra medicación, ya que pueden provocar efectos adversos y dependencia. En vista de lo anterior, este estudio tuvo como objetivo evaluar, a través de la literatura, la forma correcta de usar metilfenidato, el uso indiscriminado, off label y los problemas de salud que el uso prolongado puede desencadenar en el usuario, así como la importancia de la atención farmacéutica. para un tratamiento eficaz con metilfenidato. Para ello, se realizó una revisión integradora de la literatura y los artículos para esta revisión se recolectaron en los siguientes portales de búsqueda: SciELO, BVS y Lilacs. Después de la recopilación, se seleccionaron 21 estudios para componer los resultados. Se pudo notar que el uso indiscriminado de clorhidrato de metilfenidato ha sido realizado con frecuencia por muchas personas, especialmente por estudiantes, lo que puede derivar en complicaciones graves y la aparición de efectos adversos graves, especialmente eventos cardiovasculares como taquicardia e hipertensión, trastornos psiquiátricos. como depresión, psicosis y dependencia química, así como del sistema neurológico como discinesia, contracciones musculares involuntarias y espasmos, entre otros.O cloridato de metilfenidato [(dl-treo-metil-2-fenil-2- (2-piperidil) acetato], conhecido como Ritalina é um psicofármaco usado geralmente por pessoas com Transtorno de Déficit de Atenção e Hiperatividade (TDAH) e com narcolepsia, para o seu tratamento. Por se tratar de um medicamento que age no sistema nervoso liberando noradrenalina e dopamina nas fendas sinápticas, incidindo uma excitação nos receptores pós-sinápticos e altera as funções cognitivas do usuário, o uso off label para melhorar o desempenho cognitivo está sendo cada vez mais comum. Este tipo de medicamento deve ser usado de forma racional, bem como qualquer outra medicação, pois podem causar efeitos adversos e dependência. Em vista do exposto, este estudo objetivou avaliar, por meio da literatura, a forma correta de uso do metilfenidato, o uso indiscriminado, off label e os problemas de saúde que o uso prolongado pode desencadear no usuário, assim como a importância da atenção farmacêutica para um tratamento eficaz com metilfenidato. Para isso, foi realizada uma revisão integrativa da literatura e os artigos para esta revisão foram coletados nos seguintes portais de pesquisa: SciELO, BVS e Lilacs. Após a coleta, foram selecionados 21 estudos para compor os resultados. Foi possível perceber que o uso indiscriminado do cloridrato de metilfenidato tem sido realizado com frequência por muitas pessoas, principalmente por estudantes, podendo levar a complicações sérias e o aparecimento de efeitos adversos graves, principalmente eventos cardiovasculares como taquicardia e hipertensão, transtornos psiquiátricos como depressão, psicose e dependência química, bem como do sistema neurológico como discinesia, contrações musculares involuntárias e espasmos, entre outros.Research, Society and Development2021-08-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1910810.33448/rsd-v10i10.19108Research, Society and Development; Vol. 10 No. 10; e443101019108Research, Society and Development; Vol. 10 Núm. 10; e443101019108Research, Society and Development; v. 10 n. 10; e4431010191082525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/19108/17003Copyright (c) 2021 Natasha Costa da Rocha Galucio; Regianne Maciel dos Santos Correa; Vanessa Barbosa Ferreira; Erissâmia do Socorro da Silva Fonteles; Deusilene Braga Barbosa; Daniele de Araújo Moysés; Gleicy Kelly China Quemel; Valdicley Vieira Vale https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGalucio, Natasha Costa da Rocha Correa, Regianne Maciel dos SantosFerreira, Vanessa Barbosa Fonteles, Erissâmia do Socorro da Silva Barbosa, Deusilene Braga Moysés, Daniele de Araújo Quemel, Gleicy Kelly ChinaVale , Valdicley Vieira 2021-10-02T21:49:16Zoai:ojs.pkp.sfu.ca:article/19108Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:39:04.981038Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
The indiscriminate and off label use of Ritalin El uso indiscriminado y no autorizado de Ritalin O uso indiscriminado e off label da Ritalina |
title |
The indiscriminate and off label use of Ritalin |
spellingShingle |
The indiscriminate and off label use of Ritalin Galucio, Natasha Costa da Rocha Off label Rational use Ritalin Methylphenidate. Off label Uso racional Ritalin Metilfenidato. Off label Uso racional Ritalina Metilfenidato. |
title_short |
The indiscriminate and off label use of Ritalin |
title_full |
The indiscriminate and off label use of Ritalin |
title_fullStr |
The indiscriminate and off label use of Ritalin |
title_full_unstemmed |
The indiscriminate and off label use of Ritalin |
title_sort |
The indiscriminate and off label use of Ritalin |
author |
Galucio, Natasha Costa da Rocha |
author_facet |
Galucio, Natasha Costa da Rocha Correa, Regianne Maciel dos Santos Ferreira, Vanessa Barbosa Fonteles, Erissâmia do Socorro da Silva Barbosa, Deusilene Braga Moysés, Daniele de Araújo Quemel, Gleicy Kelly China Vale , Valdicley Vieira |
author_role |
author |
author2 |
Correa, Regianne Maciel dos Santos Ferreira, Vanessa Barbosa Fonteles, Erissâmia do Socorro da Silva Barbosa, Deusilene Braga Moysés, Daniele de Araújo Quemel, Gleicy Kelly China Vale , Valdicley Vieira |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Galucio, Natasha Costa da Rocha Correa, Regianne Maciel dos Santos Ferreira, Vanessa Barbosa Fonteles, Erissâmia do Socorro da Silva Barbosa, Deusilene Braga Moysés, Daniele de Araújo Quemel, Gleicy Kelly China Vale , Valdicley Vieira |
dc.subject.por.fl_str_mv |
Off label Rational use Ritalin Methylphenidate. Off label Uso racional Ritalin Metilfenidato. Off label Uso racional Ritalina Metilfenidato. |
topic |
Off label Rational use Ritalin Methylphenidate. Off label Uso racional Ritalin Metilfenidato. Off label Uso racional Ritalina Metilfenidato. |
description |
Methylphenidate hydrochloride [(dl-treo-metil-2-fenil-2- (2-piperidil) acetato], known as Ritalin, is a psychotropic drug commonly used by people with Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy for its treatment. As it is a drug that acts on the nervous system by releasing norepinephrine and dopamine in the synaptic clefts, causing an excitation in postsynaptic receptors and altering the user's cognitive functions, the off label use to improve cognitive performance is becoming more and more common. This type of medication must be used rationally, as well as any other medication, as they can cause adverse effects and dependence. In view of the above, this study aimed to evaluate, through the literature, the correct way to use methylphenidate, the indiscriminate use, off label and the health problems that prolonged use can trigger in the user, as well as the importance of pharmaceutical care for effective treatment with methylphenidate. For this, an integrative literature review was carried out and the articles for this review were collected in the following search portals: SciELO, BVS and Lilacs. After collection, 21 studies were selected to compose the results. It was possible to notice that the indiscriminate use of methylphenidate hydrochloride has been carried out frequently by many people, especially by students, which can lead to serious complications and the appearance of serious adverse effects, especially cardiovascular events such as tachycardia and hypertension, psychiatric disorders such as depression, psychosis and chemical dependency, as well as the neurological system such as dyskinesia, involuntary muscle contractions and spasms, among others. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-08-15 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/19108 10.33448/rsd-v10i10.19108 |
url |
https://rsdjournal.org/index.php/rsd/article/view/19108 |
identifier_str_mv |
10.33448/rsd-v10i10.19108 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/19108/17003 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 10; e443101019108 Research, Society and Development; Vol. 10 Núm. 10; e443101019108 Research, Society and Development; v. 10 n. 10; e443101019108 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052686791606272 |