Concurrent dengue and malaria in the Amazon region

Detalhes bibliográficos
Autor(a) principal: Santana, Vinicius dos Santos [UNESP]
Data de Publicação: 2010
Outros Autores: Lavezzo, Ligia Carolina [UNESP], Mondini, Adriano, Bernardes Terzian, Ana Carolina, de Moraes Bronzoni, Roberta Vieira, Baptista Rossit, Andrea Regina, Dantas Machado, Ricardo Luiz, Rahal, Paula [UNESP], Lelles Nogueira, Mara Correa, Nogueira, Mauricio Lacerda
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0037-86822010000500007
http://hdl.handle.net/11449/21603
Resumo: Introduction: The Amazon region has extensive forested areas and natural ecosystems, providing favorable conditions for the existence of innumerous arboviruses. Over 200 arboviruses have been isolated in Brazil and about 40 are associated with human disease. Four out of 40 are considered to be of public health importance in Brazil: Dengue viruses (1-4), Oropouche, Mayaro and Yellow Fever. Along with these viruses, about 98% of the malaria cases are restricted to the Legal Amazon region. Methods: This study aimed to investigate the presence of arboviruses in 111 clinical serum samples from patients living in Novo Repartimento (Para), Placido de Castro (Acre), Porto Velho (Rondonia) and Oiapoque (Amapa). The viral RNA was extracted and RT-PCR was performed followed by a Multiplex-Nested-PCR, using Flavivirus, Alphavirus and Orthobunyavirus generic and species-specific primers. Results: Dengue virus serotype 2 was detected in two patients living in Novo Repartimento (Para) that also presented active Plasmodium vivax infection. Conclusions: Despite scant data, this situation is likely to occur more frequently than detected in the Amazon region. Finally, it is important to remember that both diseases have similar clinical findings, thus the diagnosis could be made concomitantly for dengue and malaria in patients living or returning from areas where both diseases are endemic or during dengue outbreaks.
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spelling Concurrent dengue and malaria in the Amazon regionCo-infecção por dengue e malária na região AmazônicaArbovirusesCoinfectionFlavivirusesDengueMalariaAmazon regionIntroduction: The Amazon region has extensive forested areas and natural ecosystems, providing favorable conditions for the existence of innumerous arboviruses. Over 200 arboviruses have been isolated in Brazil and about 40 are associated with human disease. Four out of 40 are considered to be of public health importance in Brazil: Dengue viruses (1-4), Oropouche, Mayaro and Yellow Fever. Along with these viruses, about 98% of the malaria cases are restricted to the Legal Amazon region. Methods: This study aimed to investigate the presence of arboviruses in 111 clinical serum samples from patients living in Novo Repartimento (Para), Placido de Castro (Acre), Porto Velho (Rondonia) and Oiapoque (Amapa). The viral RNA was extracted and RT-PCR was performed followed by a Multiplex-Nested-PCR, using Flavivirus, Alphavirus and Orthobunyavirus generic and species-specific primers. Results: Dengue virus serotype 2 was detected in two patients living in Novo Repartimento (Para) that also presented active Plasmodium vivax infection. Conclusions: Despite scant data, this situation is likely to occur more frequently than detected in the Amazon region. Finally, it is important to remember that both diseases have similar clinical findings, thus the diagnosis could be made concomitantly for dengue and malaria in patients living or returning from areas where both diseases are endemic or during dengue outbreaks.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Sao Jose Rio do Preto Med Sch, Virol Lab, Sao Jose do Rio Preto, SP, BrazilSao Jose Rio do Preto Med Sch, Dept Dermatol & Infect Dis, Sao Jose do Rio Preto, SP, BrazilSão Paulo State Univ, Grad Program Microbiol, Sao Jose do Rio Preto, SP, BrazilSão Paulo State Univ, Grad Program Microbiol, Sao Jose do Rio Preto, SP, BrazilFAPESP: 2008/03828-1FAPESP: 2002/0946-1CNPq: 302353/03-8Soc Brasileira Medicina TropicalSao Jose Rio do Preto Med SchUniversidade Estadual Paulista (Unesp)Santana, Vinicius dos Santos [UNESP]Lavezzo, Ligia Carolina [UNESP]Mondini, AdrianoBernardes Terzian, Ana Carolinade Moraes Bronzoni, Roberta VieiraBaptista Rossit, Andrea ReginaDantas Machado, Ricardo LuizRahal, Paula [UNESP]Lelles Nogueira, Mara CorreaNogueira, Mauricio Lacerda2014-05-20T14:01:08Z2014-05-20T14:01:08Z2010-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article508-511application/pdfhttp://dx.doi.org/10.1590/S0037-86822010000500007Revista da Sociedade Brasileira de Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 43, n. 5, p. 508-511, 2010.0037-8682http://hdl.handle.net/11449/2160310.1590/S0037-86822010000500007S0037-86822010000500007WOS:000284589700007S0037-86822010000500007.pdf799108236267121258211426247203980000-0002-5557-97210000-0001-5693-6148Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista da Sociedade Brasileira de Medicina Tropical1.3580,658info:eu-repo/semantics/openAccess2023-11-06T06:09:23Zoai:repositorio.unesp.br:11449/21603Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:01:31.650139Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Concurrent dengue and malaria in the Amazon region
Co-infecção por dengue e malária na região Amazônica
title Concurrent dengue and malaria in the Amazon region
spellingShingle Concurrent dengue and malaria in the Amazon region
Santana, Vinicius dos Santos [UNESP]
Arboviruses
Coinfection
Flaviviruses
Dengue
Malaria
Amazon region
title_short Concurrent dengue and malaria in the Amazon region
title_full Concurrent dengue and malaria in the Amazon region
title_fullStr Concurrent dengue and malaria in the Amazon region
title_full_unstemmed Concurrent dengue and malaria in the Amazon region
title_sort Concurrent dengue and malaria in the Amazon region
author Santana, Vinicius dos Santos [UNESP]
author_facet Santana, Vinicius dos Santos [UNESP]
Lavezzo, Ligia Carolina [UNESP]
Mondini, Adriano
Bernardes Terzian, Ana Carolina
de Moraes Bronzoni, Roberta Vieira
Baptista Rossit, Andrea Regina
Dantas Machado, Ricardo Luiz
Rahal, Paula [UNESP]
Lelles Nogueira, Mara Correa
Nogueira, Mauricio Lacerda
author_role author
author2 Lavezzo, Ligia Carolina [UNESP]
Mondini, Adriano
Bernardes Terzian, Ana Carolina
de Moraes Bronzoni, Roberta Vieira
Baptista Rossit, Andrea Regina
Dantas Machado, Ricardo Luiz
Rahal, Paula [UNESP]
Lelles Nogueira, Mara Correa
Nogueira, Mauricio Lacerda
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Sao Jose Rio do Preto Med Sch
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Santana, Vinicius dos Santos [UNESP]
Lavezzo, Ligia Carolina [UNESP]
Mondini, Adriano
Bernardes Terzian, Ana Carolina
de Moraes Bronzoni, Roberta Vieira
Baptista Rossit, Andrea Regina
Dantas Machado, Ricardo Luiz
Rahal, Paula [UNESP]
Lelles Nogueira, Mara Correa
Nogueira, Mauricio Lacerda
dc.subject.por.fl_str_mv Arboviruses
Coinfection
Flaviviruses
Dengue
Malaria
Amazon region
topic Arboviruses
Coinfection
Flaviviruses
Dengue
Malaria
Amazon region
description Introduction: The Amazon region has extensive forested areas and natural ecosystems, providing favorable conditions for the existence of innumerous arboviruses. Over 200 arboviruses have been isolated in Brazil and about 40 are associated with human disease. Four out of 40 are considered to be of public health importance in Brazil: Dengue viruses (1-4), Oropouche, Mayaro and Yellow Fever. Along with these viruses, about 98% of the malaria cases are restricted to the Legal Amazon region. Methods: This study aimed to investigate the presence of arboviruses in 111 clinical serum samples from patients living in Novo Repartimento (Para), Placido de Castro (Acre), Porto Velho (Rondonia) and Oiapoque (Amapa). The viral RNA was extracted and RT-PCR was performed followed by a Multiplex-Nested-PCR, using Flavivirus, Alphavirus and Orthobunyavirus generic and species-specific primers. Results: Dengue virus serotype 2 was detected in two patients living in Novo Repartimento (Para) that also presented active Plasmodium vivax infection. Conclusions: Despite scant data, this situation is likely to occur more frequently than detected in the Amazon region. Finally, it is important to remember that both diseases have similar clinical findings, thus the diagnosis could be made concomitantly for dengue and malaria in patients living or returning from areas where both diseases are endemic or during dengue outbreaks.
publishDate 2010
dc.date.none.fl_str_mv 2010-09-01
2014-05-20T14:01:08Z
2014-05-20T14:01:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0037-86822010000500007
Revista da Sociedade Brasileira de Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 43, n. 5, p. 508-511, 2010.
0037-8682
http://hdl.handle.net/11449/21603
10.1590/S0037-86822010000500007
S0037-86822010000500007
WOS:000284589700007
S0037-86822010000500007.pdf
7991082362671212
5821142624720398
0000-0002-5557-9721
0000-0001-5693-6148
url http://dx.doi.org/10.1590/S0037-86822010000500007
http://hdl.handle.net/11449/21603
identifier_str_mv Revista da Sociedade Brasileira de Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 43, n. 5, p. 508-511, 2010.
0037-8682
10.1590/S0037-86822010000500007
S0037-86822010000500007
WOS:000284589700007
S0037-86822010000500007.pdf
7991082362671212
5821142624720398
0000-0002-5557-9721
0000-0001-5693-6148
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical
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dc.format.none.fl_str_mv 508-511
application/pdf
dc.publisher.none.fl_str_mv Soc Brasileira Medicina Tropical
publisher.none.fl_str_mv Soc Brasileira Medicina Tropical
dc.source.none.fl_str_mv Web of Science
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repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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