Single-cell transcriptomics reveals hidden information in trypanosomatids

Detalhes bibliográficos
Autor(a) principal: Abuchery, Bryan E. [UNESP]
Data de Publicação: 2022
Outros Autores: Black, Jennifer A., da Silva, Marcelo S. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.pt.2021.10.006
http://hdl.handle.net/11449/222848
Resumo: Dixenic parasites often encounter environmental extremes during the transition from vector to host. Preadapted transmission stages overcome these challenges to promote parasites' survival and ensure life cycle progression. Recently, Vigneron et al. and Briggs et al. used single-cell transcriptomics to investigate developmental stage specific gene expression patterns during parasite differentiation.
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spelling Single-cell transcriptomics reveals hidden information in trypanosomatidsscRNA-seqtranscriptometransmissionTrypanosoma bruceiDixenic parasites often encounter environmental extremes during the transition from vector to host. Preadapted transmission stages overcome these challenges to promote parasites' survival and ensure life cycle progression. Recently, Vigneron et al. and Briggs et al. used single-cell transcriptomics to investigate developmental stage specific gene expression patterns during parasite differentiation.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)DNA Replication and Repair Laboratory Department of Chemical and Biological Sciences Institute of Biosciences São Paulo State University (UNESP)Faculty of Medicine of Ribeirão Preto University of São PauloThe Wellcome Centre for Integrative Parasitology Institute of Infection Immunity and Inflammation University of GlasgowDNA Replication and Repair Laboratory Department of Chemical and Biological Sciences Institute of Biosciences São Paulo State University (UNESP)FAPESP: 2019/10753-2FAPESP: 2020/01883-7FAPESP: 2020/10277-3FAPESP: 2020/16480-5Universidade Estadual Paulista (UNESP)Universidade de São Paulo (USP)University of GlasgowAbuchery, Bryan E. [UNESP]Black, Jennifer A.da Silva, Marcelo S. [UNESP]2022-04-28T19:47:08Z2022-04-28T19:47:08Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article4-6http://dx.doi.org/10.1016/j.pt.2021.10.006Trends in Parasitology, v. 38, n. 1, p. 4-6, 2022.1471-50071471-4922http://hdl.handle.net/11449/22284810.1016/j.pt.2021.10.0062-s2.0-85118968494Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTrends in Parasitologyinfo:eu-repo/semantics/openAccess2022-04-28T19:47:08Zoai:repositorio.unesp.br:11449/222848Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T19:47:08Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Single-cell transcriptomics reveals hidden information in trypanosomatids
title Single-cell transcriptomics reveals hidden information in trypanosomatids
spellingShingle Single-cell transcriptomics reveals hidden information in trypanosomatids
Abuchery, Bryan E. [UNESP]
scRNA-seq
transcriptome
transmission
Trypanosoma brucei
title_short Single-cell transcriptomics reveals hidden information in trypanosomatids
title_full Single-cell transcriptomics reveals hidden information in trypanosomatids
title_fullStr Single-cell transcriptomics reveals hidden information in trypanosomatids
title_full_unstemmed Single-cell transcriptomics reveals hidden information in trypanosomatids
title_sort Single-cell transcriptomics reveals hidden information in trypanosomatids
author Abuchery, Bryan E. [UNESP]
author_facet Abuchery, Bryan E. [UNESP]
Black, Jennifer A.
da Silva, Marcelo S. [UNESP]
author_role author
author2 Black, Jennifer A.
da Silva, Marcelo S. [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Universidade de São Paulo (USP)
University of Glasgow
dc.contributor.author.fl_str_mv Abuchery, Bryan E. [UNESP]
Black, Jennifer A.
da Silva, Marcelo S. [UNESP]
dc.subject.por.fl_str_mv scRNA-seq
transcriptome
transmission
Trypanosoma brucei
topic scRNA-seq
transcriptome
transmission
Trypanosoma brucei
description Dixenic parasites often encounter environmental extremes during the transition from vector to host. Preadapted transmission stages overcome these challenges to promote parasites' survival and ensure life cycle progression. Recently, Vigneron et al. and Briggs et al. used single-cell transcriptomics to investigate developmental stage specific gene expression patterns during parasite differentiation.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-28T19:47:08Z
2022-04-28T19:47:08Z
2022-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.pt.2021.10.006
Trends in Parasitology, v. 38, n. 1, p. 4-6, 2022.
1471-5007
1471-4922
http://hdl.handle.net/11449/222848
10.1016/j.pt.2021.10.006
2-s2.0-85118968494
url http://dx.doi.org/10.1016/j.pt.2021.10.006
http://hdl.handle.net/11449/222848
identifier_str_mv Trends in Parasitology, v. 38, n. 1, p. 4-6, 2022.
1471-5007
1471-4922
10.1016/j.pt.2021.10.006
2-s2.0-85118968494
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Trends in Parasitology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 4-6
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799965043769475072

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