Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series

Detalhes bibliográficos
Autor(a) principal: Baldi, Bruno Guedes
Data de Publicação: 2022
Outros Autores: Fabro, Alexandre Todorovic, Franco, Andreia Craveiro [UNESP], Machado, Marília Helena C. [UNESP], Prudente, Robson Aparecido [UNESP], Franco, Estefânia Thomé [UNESP], Marrone, Sergio Ribeiro [UNESP], Vale, Simone Alves do [UNESP], Cezare, Talita Jacon [UNESP], Moraes, Marcelo Padovani de Toledo, Ferreira, Eloara Vieira Machado, Albuquerque, André Luis Pereira, Sawamura, Marcio Valente Yamada, Tanni, Suzana Erico [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.36416/1806-3756/e20210438
http://hdl.handle.net/11449/240933
Resumo: This brief communication demonstrates the correlation of persistent respiratory symptoms with functional, tomographic, and transbronchial pulmonary biopsy findings in patients with COVID-19 who had a long follow-up period. We report a series of six COVID-19 patients with pulmonary involvement who presented with persistent dyspnea within 4-15 months of discharge. We performed transbronchial biopsies, and the histopathological pattern consistently demonstrated peribronchial remodeling with interstitial pulmonary fibrosis. Therefore, lung biopsy may be useful in the approach of patients with long COVID-19, although the type of procedure, its precise indication, and the moment to perform it are yet to be clarified. (Brazilian Registry of Clinical Trials–ReBEC; identifier: RBR-8j9kqy [http://www. ensaiosclinicos.gov.br]).
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spelling Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case seriesBiopsyCOVID-19COVID-19/pathologyPulmonary fibrosisRespiratory function testsThis brief communication demonstrates the correlation of persistent respiratory symptoms with functional, tomographic, and transbronchial pulmonary biopsy findings in patients with COVID-19 who had a long follow-up period. We report a series of six COVID-19 patients with pulmonary involvement who presented with persistent dyspnea within 4-15 months of discharge. We performed transbronchial biopsies, and the histopathological pattern consistently demonstrated peribronchial remodeling with interstitial pulmonary fibrosis. Therefore, lung biopsy may be useful in the approach of patients with long COVID-19, although the type of procedure, its precise indication, and the moment to perform it are yet to be clarified. (Brazilian Registry of Clinical Trials–ReBEC; identifier: RBR-8j9kqy [http://www. ensaiosclinicos.gov.br]).Divisão de Pneumologia Instituto do Coração – InCor – Hospital das Clínicas Faculdade de Medicina Universidade de São Paulo, SPDepartamento de Patologia e Medicina Legal Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo – USP, SPDisciplina de Pneumologia Departamento de Clínica Médica Faculdade de Medicina de Botucatu Universidade Estadual Paulista, SPDisciplina de Radiologia Departamento de Dermatologia e Radioterapia Faculdade de Medicina de Botucatu Universidade Estadual Paulista, SPDisciplina de Pneumologia Departamento de Medicina Universidade Federal de São Paulo – UNIFESP, SPInstituto de Radiologia Hospital das Clínicas Faculdade de Medicina Universidade de São Paulo, SPDisciplina de Pneumologia Departamento de Clínica Médica Faculdade de Medicina de Botucatu Universidade Estadual Paulista, SPDisciplina de Radiologia Departamento de Dermatologia e Radioterapia Faculdade de Medicina de Botucatu Universidade Estadual Paulista, SPUniversidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)Universidade Federal de São Paulo (UNIFESP)Baldi, Bruno GuedesFabro, Alexandre TodorovicFranco, Andreia Craveiro [UNESP]Machado, Marília Helena C. [UNESP]Prudente, Robson Aparecido [UNESP]Franco, Estefânia Thomé [UNESP]Marrone, Sergio Ribeiro [UNESP]Vale, Simone Alves do [UNESP]Cezare, Talita Jacon [UNESP]Moraes, Marcelo Padovani de ToledoFerreira, Eloara Vieira MachadoAlbuquerque, André Luis PereiraSawamura, Marcio Valente YamadaTanni, Suzana Erico [UNESP]2023-03-01T20:39:08Z2023-03-01T20:39:08Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.36416/1806-3756/e20210438Jornal Brasileiro de Pneumologia, v. 48, n. 3, 2022.1806-37561806-3713http://hdl.handle.net/11449/24093310.36416/1806-3756/e202104382-s2.0-85129406799Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJornal Brasileiro de Pneumologiainfo:eu-repo/semantics/openAccess2024-08-14T18:45:08Zoai:repositorio.unesp.br:11449/240933Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T18:45:08Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series
title Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series
spellingShingle Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series
Baldi, Bruno Guedes
Biopsy
COVID-19
COVID-19/pathology
Pulmonary fibrosis
Respiratory function tests
title_short Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series
title_full Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series
title_fullStr Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series
title_full_unstemmed Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series
title_sort Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series
author Baldi, Bruno Guedes
author_facet Baldi, Bruno Guedes
Fabro, Alexandre Todorovic
Franco, Andreia Craveiro [UNESP]
Machado, Marília Helena C. [UNESP]
Prudente, Robson Aparecido [UNESP]
Franco, Estefânia Thomé [UNESP]
Marrone, Sergio Ribeiro [UNESP]
Vale, Simone Alves do [UNESP]
Cezare, Talita Jacon [UNESP]
Moraes, Marcelo Padovani de Toledo
Ferreira, Eloara Vieira Machado
Albuquerque, André Luis Pereira
Sawamura, Marcio Valente Yamada
Tanni, Suzana Erico [UNESP]
author_role author
author2 Fabro, Alexandre Todorovic
Franco, Andreia Craveiro [UNESP]
Machado, Marília Helena C. [UNESP]
Prudente, Robson Aparecido [UNESP]
Franco, Estefânia Thomé [UNESP]
Marrone, Sergio Ribeiro [UNESP]
Vale, Simone Alves do [UNESP]
Cezare, Talita Jacon [UNESP]
Moraes, Marcelo Padovani de Toledo
Ferreira, Eloara Vieira Machado
Albuquerque, André Luis Pereira
Sawamura, Marcio Valente Yamada
Tanni, Suzana Erico [UNESP]
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Estadual Paulista (UNESP)
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Baldi, Bruno Guedes
Fabro, Alexandre Todorovic
Franco, Andreia Craveiro [UNESP]
Machado, Marília Helena C. [UNESP]
Prudente, Robson Aparecido [UNESP]
Franco, Estefânia Thomé [UNESP]
Marrone, Sergio Ribeiro [UNESP]
Vale, Simone Alves do [UNESP]
Cezare, Talita Jacon [UNESP]
Moraes, Marcelo Padovani de Toledo
Ferreira, Eloara Vieira Machado
Albuquerque, André Luis Pereira
Sawamura, Marcio Valente Yamada
Tanni, Suzana Erico [UNESP]
dc.subject.por.fl_str_mv Biopsy
COVID-19
COVID-19/pathology
Pulmonary fibrosis
Respiratory function tests
topic Biopsy
COVID-19
COVID-19/pathology
Pulmonary fibrosis
Respiratory function tests
description This brief communication demonstrates the correlation of persistent respiratory symptoms with functional, tomographic, and transbronchial pulmonary biopsy findings in patients with COVID-19 who had a long follow-up period. We report a series of six COVID-19 patients with pulmonary involvement who presented with persistent dyspnea within 4-15 months of discharge. We performed transbronchial biopsies, and the histopathological pattern consistently demonstrated peribronchial remodeling with interstitial pulmonary fibrosis. Therefore, lung biopsy may be useful in the approach of patients with long COVID-19, although the type of procedure, its precise indication, and the moment to perform it are yet to be clarified. (Brazilian Registry of Clinical Trials–ReBEC; identifier: RBR-8j9kqy [http://www. ensaiosclinicos.gov.br]).
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
2023-03-01T20:39:08Z
2023-03-01T20:39:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.36416/1806-3756/e20210438
Jornal Brasileiro de Pneumologia, v. 48, n. 3, 2022.
1806-3756
1806-3713
http://hdl.handle.net/11449/240933
10.36416/1806-3756/e20210438
2-s2.0-85129406799
url http://dx.doi.org/10.36416/1806-3756/e20210438
http://hdl.handle.net/11449/240933
identifier_str_mv Jornal Brasileiro de Pneumologia, v. 48, n. 3, 2022.
1806-3756
1806-3713
10.36416/1806-3756/e20210438
2-s2.0-85129406799
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Jornal Brasileiro de Pneumologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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