Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://connection.ebscohost.com/c/articles/90307465/segmentation-cell-nuclei-regions-epithelium-prostate-glands http://hdl.handle.net/11449/122835 |
Resumo: | This paper proposes a method for segmentation of cell nuclei regions in epithelium of prostate glands. This structure provides information to diagnosis and prognosis of prostate cancer. In the initial step, the contrast stretching technique was applied in image in order to improve the contrast between regions of interest and other regions. After, the global thresholding technique was applied and the value of threshold was defined empirically. Finally, the false positive regions were removed using the connected components technique. The performance of the proposed method was compared with the Otsu technique and statistical measures of accuracy were calculated based on reference images (gold standard). The result of the mean value of accuracy of proposed method was 93% ± 0.07. |
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Repositório Institucional da UNESP |
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2946 |
spelling |
Segmentation of Cell Nuclei Regions in Epithelium of Prostate GlandsCell Nuclei Regions SegmentationHistological SegmentationProstate GlandsDigital PathologyContrast StretchingGlobal ThresholdingThis paper proposes a method for segmentation of cell nuclei regions in epithelium of prostate glands. This structure provides information to diagnosis and prognosis of prostate cancer. In the initial step, the contrast stretching technique was applied in image in order to improve the contrast between regions of interest and other regions. After, the global thresholding technique was applied and the value of threshold was defined empirically. Finally, the false positive regions were removed using the connected components technique. The performance of the proposed method was compared with the Otsu technique and statistical measures of accuracy were calculated based on reference images (gold standard). The result of the mean value of accuracy of proposed method was 93% ± 0.07.Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Ciência da Computação e Estatística, Instituto de Biociências Letras e Ciências Exatas de São José do Rio Preto, São José do Rio Preto, Rua Cristóvão Colombo, 2265, Jardim Nazareth, CEP 15054000, SP, BrasilUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Ciência da Computação e Estatística, Instituto de Biociências Letras e Ciências Exatas de São José do Rio Preto, São José do Rio Preto, Rua Cristóvão Colombo, 2265, Jardim Nazareth, CEP 15054000, SP, BrasilUniversidade Estadual Paulista (Unesp)Oliveira, Domingos Lucas Latore deNascimento, Marcelo Zanchetta doNeves, Leandro Alves [UNESP]Godoy, Moacir F.Arruda, Pedro Francisco Ferraz deSanti Neto, Dalisio de2015-04-27T11:56:05Z2015-04-27T11:56:05Z2012info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article21-24http://connection.ebscohost.com/c/articles/90307465/segmentation-cell-nuclei-regions-epithelium-prostate-glandsJournal of Modelling and Simulation of Systems, v. 3, n. 1, p. 21-24, 2012.1737-9377http://hdl.handle.net/11449/12283558010242664322652139053814879312Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Modelling and Simulation of Systemsinfo:eu-repo/semantics/openAccess2021-10-22T20:11:38Zoai:repositorio.unesp.br:11449/122835Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:19:41.799024Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands |
title |
Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands |
spellingShingle |
Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands Oliveira, Domingos Lucas Latore de Cell Nuclei Regions Segmentation Histological Segmentation Prostate Glands Digital Pathology Contrast Stretching Global Thresholding |
title_short |
Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands |
title_full |
Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands |
title_fullStr |
Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands |
title_full_unstemmed |
Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands |
title_sort |
Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands |
author |
Oliveira, Domingos Lucas Latore de |
author_facet |
Oliveira, Domingos Lucas Latore de Nascimento, Marcelo Zanchetta do Neves, Leandro Alves [UNESP] Godoy, Moacir F. Arruda, Pedro Francisco Ferraz de Santi Neto, Dalisio de |
author_role |
author |
author2 |
Nascimento, Marcelo Zanchetta do Neves, Leandro Alves [UNESP] Godoy, Moacir F. Arruda, Pedro Francisco Ferraz de Santi Neto, Dalisio de |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Oliveira, Domingos Lucas Latore de Nascimento, Marcelo Zanchetta do Neves, Leandro Alves [UNESP] Godoy, Moacir F. Arruda, Pedro Francisco Ferraz de Santi Neto, Dalisio de |
dc.subject.por.fl_str_mv |
Cell Nuclei Regions Segmentation Histological Segmentation Prostate Glands Digital Pathology Contrast Stretching Global Thresholding |
topic |
Cell Nuclei Regions Segmentation Histological Segmentation Prostate Glands Digital Pathology Contrast Stretching Global Thresholding |
description |
This paper proposes a method for segmentation of cell nuclei regions in epithelium of prostate glands. This structure provides information to diagnosis and prognosis of prostate cancer. In the initial step, the contrast stretching technique was applied in image in order to improve the contrast between regions of interest and other regions. After, the global thresholding technique was applied and the value of threshold was defined empirically. Finally, the false positive regions were removed using the connected components technique. The performance of the proposed method was compared with the Otsu technique and statistical measures of accuracy were calculated based on reference images (gold standard). The result of the mean value of accuracy of proposed method was 93% ± 0.07. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012 2015-04-27T11:56:05Z 2015-04-27T11:56:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://connection.ebscohost.com/c/articles/90307465/segmentation-cell-nuclei-regions-epithelium-prostate-glands Journal of Modelling and Simulation of Systems, v. 3, n. 1, p. 21-24, 2012. 1737-9377 http://hdl.handle.net/11449/122835 5801024266432265 2139053814879312 |
url |
http://connection.ebscohost.com/c/articles/90307465/segmentation-cell-nuclei-regions-epithelium-prostate-glands http://hdl.handle.net/11449/122835 |
identifier_str_mv |
Journal of Modelling and Simulation of Systems, v. 3, n. 1, p. 21-24, 2012. 1737-9377 5801024266432265 2139053814879312 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Modelling and Simulation of Systems |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
21-24 |
dc.source.none.fl_str_mv |
Currículo Lattes reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128791485087744 |