Galleria mellonella as a model host for human pathogens: recent studies and new perspectives

Detalhes bibliográficos
Autor(a) principal: Junqueira, Juliana Campos [UNESP]
Data de Publicação: 2012
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.4161/viru.22493
http://hdl.handle.net/11449/132404
Resumo: The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories.
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spelling Galleria mellonella as a model host for human pathogens: recent studies and new perspectivesInsect proteinAnimalCandida albicansCandidiasisImmunologyLarvaMetabolismMothNoteAnimalsCandidiasisInsect ProteinsLarvaMothsThe number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ Estadual Paulista UNESP, Sao Jose dos Campos Dent Sch, Dept Biosci & Oral Diag, São Paulo, BrazilUniv Estadual Paulista UNESP, Sao Jose dos Campos Dent Sch, Dept Biosci & Oral Diag, São Paulo, BrazilFAPESP: 12/02184-9Universidade Estadual Paulista (Unesp)Junqueira, Juliana Campos [UNESP]2014-05-27T11:27:05Z2014-05-27T11:27:05Z2012-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article474-476application/pdfhttp://dx.doi.org/10.4161/viru.22493Virulence, v. 3, n. 6, p. 474-476, 2012.2150-5608http://hdl.handle.net/11449/13240410.4161/viru.22493WOS:0003120003000022-s2.0-848793052412-s2.0-84879305241.pdf0322020541055900Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVirulence1,635info:eu-repo/semantics/openAccess2024-01-12T06:26:29Zoai:repositorio.unesp.br:11449/132404Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-12T06:26:29Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
title Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
spellingShingle Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
Junqueira, Juliana Campos [UNESP]
Insect protein
Animal
Candida albicans
Candidiasis
Immunology
Larva
Metabolism
Moth
Note
Animals
Candidiasis
Insect Proteins
Larva
Moths
title_short Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
title_full Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
title_fullStr Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
title_full_unstemmed Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
title_sort Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
author Junqueira, Juliana Campos [UNESP]
author_facet Junqueira, Juliana Campos [UNESP]
author_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Junqueira, Juliana Campos [UNESP]
dc.subject.por.fl_str_mv Insect protein
Animal
Candida albicans
Candidiasis
Immunology
Larva
Metabolism
Moth
Note
Animals
Candidiasis
Insect Proteins
Larva
Moths
topic Insect protein
Animal
Candida albicans
Candidiasis
Immunology
Larva
Metabolism
Moth
Note
Animals
Candidiasis
Insect Proteins
Larva
Moths
description The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories.
publishDate 2012
dc.date.none.fl_str_mv 2012-10-01
2014-05-27T11:27:05Z
2014-05-27T11:27:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4161/viru.22493
Virulence, v. 3, n. 6, p. 474-476, 2012.
2150-5608
http://hdl.handle.net/11449/132404
10.4161/viru.22493
WOS:000312000300002
2-s2.0-84879305241
2-s2.0-84879305241.pdf
0322020541055900
url http://dx.doi.org/10.4161/viru.22493
http://hdl.handle.net/11449/132404
identifier_str_mv Virulence, v. 3, n. 6, p. 474-476, 2012.
2150-5608
10.4161/viru.22493
WOS:000312000300002
2-s2.0-84879305241
2-s2.0-84879305241.pdf
0322020541055900
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Virulence
1,635
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 474-476
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799965596089057280

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