Galleria mellonella as a model host for human pathogens: recent studies and new perspectives
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.4161/viru.22493 http://hdl.handle.net/11449/132404 |
Resumo: | The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories. |
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Galleria mellonella as a model host for human pathogens: recent studies and new perspectivesInsect proteinAnimalCandida albicansCandidiasisImmunologyLarvaMetabolismMothNoteAnimalsCandidiasisInsect ProteinsLarvaMothsThe number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ Estadual Paulista UNESP, Sao Jose dos Campos Dent Sch, Dept Biosci & Oral Diag, São Paulo, BrazilUniv Estadual Paulista UNESP, Sao Jose dos Campos Dent Sch, Dept Biosci & Oral Diag, São Paulo, BrazilFAPESP: 12/02184-9Universidade Estadual Paulista (Unesp)Junqueira, Juliana Campos [UNESP]2014-05-27T11:27:05Z2014-05-27T11:27:05Z2012-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article474-476application/pdfhttp://dx.doi.org/10.4161/viru.22493Virulence, v. 3, n. 6, p. 474-476, 2012.2150-5608http://hdl.handle.net/11449/13240410.4161/viru.22493WOS:0003120003000022-s2.0-848793052412-s2.0-84879305241.pdf0322020541055900Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVirulence1,635info:eu-repo/semantics/openAccess2024-01-12T06:26:29Zoai:repositorio.unesp.br:11449/132404Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:45:41.251662Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Galleria mellonella as a model host for human pathogens: recent studies and new perspectives |
title |
Galleria mellonella as a model host for human pathogens: recent studies and new perspectives |
spellingShingle |
Galleria mellonella as a model host for human pathogens: recent studies and new perspectives Junqueira, Juliana Campos [UNESP] Insect protein Animal Candida albicans Candidiasis Immunology Larva Metabolism Moth Note Animals Candidiasis Insect Proteins Larva Moths |
title_short |
Galleria mellonella as a model host for human pathogens: recent studies and new perspectives |
title_full |
Galleria mellonella as a model host for human pathogens: recent studies and new perspectives |
title_fullStr |
Galleria mellonella as a model host for human pathogens: recent studies and new perspectives |
title_full_unstemmed |
Galleria mellonella as a model host for human pathogens: recent studies and new perspectives |
title_sort |
Galleria mellonella as a model host for human pathogens: recent studies and new perspectives |
author |
Junqueira, Juliana Campos [UNESP] |
author_facet |
Junqueira, Juliana Campos [UNESP] |
author_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Junqueira, Juliana Campos [UNESP] |
dc.subject.por.fl_str_mv |
Insect protein Animal Candida albicans Candidiasis Immunology Larva Metabolism Moth Note Animals Candidiasis Insect Proteins Larva Moths |
topic |
Insect protein Animal Candida albicans Candidiasis Immunology Larva Metabolism Moth Note Animals Candidiasis Insect Proteins Larva Moths |
description |
The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-10-01 2014-05-27T11:27:05Z 2014-05-27T11:27:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.4161/viru.22493 Virulence, v. 3, n. 6, p. 474-476, 2012. 2150-5608 http://hdl.handle.net/11449/132404 10.4161/viru.22493 WOS:000312000300002 2-s2.0-84879305241 2-s2.0-84879305241.pdf 0322020541055900 |
url |
http://dx.doi.org/10.4161/viru.22493 http://hdl.handle.net/11449/132404 |
identifier_str_mv |
Virulence, v. 3, n. 6, p. 474-476, 2012. 2150-5608 10.4161/viru.22493 WOS:000312000300002 2-s2.0-84879305241 2-s2.0-84879305241.pdf 0322020541055900 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Virulence 1,635 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
474-476 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129460782759936 |