Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensors
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.jmmm.2023.170835 http://hdl.handle.net/11449/247491 |
Resumo: | Micro and nanostructured magnetic materials (MNMMs) are materials with great potential for several biomedical applications, due to their magnetic properties and small size. However, for better targeting process efficiency, techniques capable of detecting, locating and imaging MNMMs within the organism are necessary. Currently there are some techniques available, but with some disadvantages such as high cost, lack of portability, and restrictions for animal experimentation. Thus, Alternating Current Biosusceptometry (ACB) is an alternative biomagnetic technique capable of detecting and performing quantitative imaging of MNMMs in vitro, ex vivo, in vivo, and in real-time. So far, the ACB results presented were restricted to quantitative planar images. To generate quantitative tomographic images using the ACB, we propose an octagonal array of pick-up and excitation coils arranged in an octagonal geometry, enabling acquisition in different projections. This configuration formed by multiple pick-up and excitation coils allowed us to test different methods and setups of coils activation. These different methods and setups enabled a deeper analysis of the ACB inverse problem stability and details. The results showed that the addition of pick-up coils resulted in a better reconstruction due to the amount of information added to the problem. Here we show for the first time the ACB quantitative tomographic reconstruction of magnetic materials distribution. |
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Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensorsAlternating current biosusceptometryMicro and nano magnetic materialsQuantitative and tomographic imagingMicro and nanostructured magnetic materials (MNMMs) are materials with great potential for several biomedical applications, due to their magnetic properties and small size. However, for better targeting process efficiency, techniques capable of detecting, locating and imaging MNMMs within the organism are necessary. Currently there are some techniques available, but with some disadvantages such as high cost, lack of portability, and restrictions for animal experimentation. Thus, Alternating Current Biosusceptometry (ACB) is an alternative biomagnetic technique capable of detecting and performing quantitative imaging of MNMMs in vitro, ex vivo, in vivo, and in real-time. So far, the ACB results presented were restricted to quantitative planar images. To generate quantitative tomographic images using the ACB, we propose an octagonal array of pick-up and excitation coils arranged in an octagonal geometry, enabling acquisition in different projections. This configuration formed by multiple pick-up and excitation coils allowed us to test different methods and setups of coils activation. These different methods and setups enabled a deeper analysis of the ACB inverse problem stability and details. The results showed that the addition of pick-up coils resulted in a better reconstruction due to the amount of information added to the problem. Here we show for the first time the ACB quantitative tomographic reconstruction of magnetic materials distribution.Biosciences Institute of Botucatu São Paulo State University, São PauloFaculty of Philosophy Sciences and Letters at Ribeirão Preto University of São Paulo, Ribeirão Preto 14040-900, Sao PauloPhysikalisch-Technische Bundesanstalt, Abbestraße 2–12Biosciences Institute of Botucatu São Paulo State University, São PauloUniversidade Estadual Paulista (UNESP)Universidade de São Paulo (USP)Physikalisch-Technische BundesanstaltPereira Buranello, Lais [UNESP]Gustavo de Albuquerque Biasotti, Gabriel [UNESP]Gonçalves Próspero, André [UNESP]Guilherme Stoppa, Erick [UNESP]Augusto Soares, Guilherme [UNESP]Baffa, OswaldoWiekhorst, FrankRicardo de Arruda Miranda, José [UNESP]2023-07-29T13:17:31Z2023-07-29T13:17:31Z2023-08-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.jmmm.2023.170835Journal of Magnetism and Magnetic Materials, v. 579.0304-8853http://hdl.handle.net/11449/24749110.1016/j.jmmm.2023.1708352-s2.0-85160702961Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Magnetism and Magnetic Materialsinfo:eu-repo/semantics/openAccess2023-07-29T13:17:31Zoai:repositorio.unesp.br:11449/247491Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:52:45.563718Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensors |
title |
Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensors |
spellingShingle |
Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensors Pereira Buranello, Lais [UNESP] Alternating current biosusceptometry Micro and nano magnetic materials Quantitative and tomographic imaging |
title_short |
Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensors |
title_full |
Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensors |
title_fullStr |
Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensors |
title_full_unstemmed |
Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensors |
title_sort |
Development and implementation of a tomographic system for the quantitative reconstruction of magnetic microparticles based on AC biosusceptometry sensors |
author |
Pereira Buranello, Lais [UNESP] |
author_facet |
Pereira Buranello, Lais [UNESP] Gustavo de Albuquerque Biasotti, Gabriel [UNESP] Gonçalves Próspero, André [UNESP] Guilherme Stoppa, Erick [UNESP] Augusto Soares, Guilherme [UNESP] Baffa, Oswaldo Wiekhorst, Frank Ricardo de Arruda Miranda, José [UNESP] |
author_role |
author |
author2 |
Gustavo de Albuquerque Biasotti, Gabriel [UNESP] Gonçalves Próspero, André [UNESP] Guilherme Stoppa, Erick [UNESP] Augusto Soares, Guilherme [UNESP] Baffa, Oswaldo Wiekhorst, Frank Ricardo de Arruda Miranda, José [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade de São Paulo (USP) Physikalisch-Technische Bundesanstalt |
dc.contributor.author.fl_str_mv |
Pereira Buranello, Lais [UNESP] Gustavo de Albuquerque Biasotti, Gabriel [UNESP] Gonçalves Próspero, André [UNESP] Guilherme Stoppa, Erick [UNESP] Augusto Soares, Guilherme [UNESP] Baffa, Oswaldo Wiekhorst, Frank Ricardo de Arruda Miranda, José [UNESP] |
dc.subject.por.fl_str_mv |
Alternating current biosusceptometry Micro and nano magnetic materials Quantitative and tomographic imaging |
topic |
Alternating current biosusceptometry Micro and nano magnetic materials Quantitative and tomographic imaging |
description |
Micro and nanostructured magnetic materials (MNMMs) are materials with great potential for several biomedical applications, due to their magnetic properties and small size. However, for better targeting process efficiency, techniques capable of detecting, locating and imaging MNMMs within the organism are necessary. Currently there are some techniques available, but with some disadvantages such as high cost, lack of portability, and restrictions for animal experimentation. Thus, Alternating Current Biosusceptometry (ACB) is an alternative biomagnetic technique capable of detecting and performing quantitative imaging of MNMMs in vitro, ex vivo, in vivo, and in real-time. So far, the ACB results presented were restricted to quantitative planar images. To generate quantitative tomographic images using the ACB, we propose an octagonal array of pick-up and excitation coils arranged in an octagonal geometry, enabling acquisition in different projections. This configuration formed by multiple pick-up and excitation coils allowed us to test different methods and setups of coils activation. These different methods and setups enabled a deeper analysis of the ACB inverse problem stability and details. The results showed that the addition of pick-up coils resulted in a better reconstruction due to the amount of information added to the problem. Here we show for the first time the ACB quantitative tomographic reconstruction of magnetic materials distribution. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T13:17:31Z 2023-07-29T13:17:31Z 2023-08-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.jmmm.2023.170835 Journal of Magnetism and Magnetic Materials, v. 579. 0304-8853 http://hdl.handle.net/11449/247491 10.1016/j.jmmm.2023.170835 2-s2.0-85160702961 |
url |
http://dx.doi.org/10.1016/j.jmmm.2023.170835 http://hdl.handle.net/11449/247491 |
identifier_str_mv |
Journal of Magnetism and Magnetic Materials, v. 579. 0304-8853 10.1016/j.jmmm.2023.170835 2-s2.0-85160702961 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Magnetism and Magnetic Materials |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808128576182026240 |