Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.rvsc.201.8.10.004 http://hdl.handle.net/11449/186512 |
Resumo: | Few data exist on the physiological consequences of an incremental exercise test (IET) and training in dogs. Here we evaluated the effect of an endurance-training program (ETP) on the kinetics of the serum biomarkers: creatine kinase (CK), aspartate aminotransferase (AST), myoglobin, cardiac troponin I (cTnI), and creatine kinase isoenzyme MB (CK-MB). Eighteen Beagle dogs were assigned to three groups: sedentary (S), untrained (U), and trained (T). The dogs from the groups T and U underwent IET, and their lactate threshold (LT) was determined. The LT and velocity corresponding to the LT (VLT) was determined by visual inspection. The VLT was utilized to determine the training intensity level. Thus, the dogs from group T underwent an eight-week aerobic conditioning program with the intensity training set to 70-80% of the VLT. Next, dogs from the groups T and U have submitted to IET again. The group S did not undergo IETs or training. The maximal velocity (Vmax) at which the dog achieves in the IET and heart rate were determined. For biomarkers, venous blood samples were collected before the experimental procedure (baseline) and before and 1, 6, 12, 24, 48, and 72 h after the IETs. VLT and Vmax increased in group T (P < .05), indicating an improvement in dogs' aerobic and anaerobic fitness. CK and AST rose (P < .05), peaking 6 h after both IETs and returning to baseline levels after 12-24 h. Levels of cTnI and myoglobin were unaltered. CK-MB peaked 1 h after the IETs and returned to baseline levels after 12 h (P < .05). We concluded that ETP improved the aerobic capacity of the dogs without any skeletal or cardiac muscle injury. |
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Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogscreatine kinaseaspartate aminotransferasemyoglobincardiac troponin Ilactateheart rateFew data exist on the physiological consequences of an incremental exercise test (IET) and training in dogs. Here we evaluated the effect of an endurance-training program (ETP) on the kinetics of the serum biomarkers: creatine kinase (CK), aspartate aminotransferase (AST), myoglobin, cardiac troponin I (cTnI), and creatine kinase isoenzyme MB (CK-MB). Eighteen Beagle dogs were assigned to three groups: sedentary (S), untrained (U), and trained (T). The dogs from the groups T and U underwent IET, and their lactate threshold (LT) was determined. The LT and velocity corresponding to the LT (VLT) was determined by visual inspection. The VLT was utilized to determine the training intensity level. Thus, the dogs from group T underwent an eight-week aerobic conditioning program with the intensity training set to 70-80% of the VLT. Next, dogs from the groups T and U have submitted to IET again. The group S did not undergo IETs or training. The maximal velocity (Vmax) at which the dog achieves in the IET and heart rate were determined. For biomarkers, venous blood samples were collected before the experimental procedure (baseline) and before and 1, 6, 12, 24, 48, and 72 h after the IETs. VLT and Vmax increased in group T (P < .05), indicating an improvement in dogs' aerobic and anaerobic fitness. CK and AST rose (P < .05), peaking 6 h after both IETs and returning to baseline levels after 12-24 h. Levels of cTnI and myoglobin were unaltered. CK-MB peaked 1 h after the IETs and returned to baseline levels after 12 h (P < .05). We concluded that ETP improved the aerobic capacity of the dogs without any skeletal or cardiac muscle injury.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Sao Paulo State Univ UNESP, Sch Agr & Veterinarian Sci, BR-14884900 Jaboticabal, SP, BrazilSao Paulo State Univ UNESP, Sch Agr & Veterinarian Sci, BR-14884900 Jaboticabal, SP, BrazilFAPESP: 2013/00449-8Elsevier B.V.Universidade Estadual Paulista (Unesp)Cerqueira, Juliana Aparecida [UNESP]Zamora Restan, Wilmer Alejandro [UNESP]Fonseca, Mayara Goncalves [UNESP]Catananti, Lucas Azevedo [UNESP]Mendes de Almeida, Maria Luiza [UNESP]Feringer Junior, Walter Heinz [UNESP]Pereira, Gener Tadeu [UNESP]Carciofi, Aulus Cavalieri [UNESP]Ferraz, Guilherme de Camargo [UNESP]2019-10-05T04:10:17Z2019-10-05T04:10:17Z2018-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article31-39http://dx.doi.org/10.1016/j.rvsc.201.8.10.004Research In Veterinary Science. Oxford: Elsevier Sci Ltd, v. 121, p. 31-39, 2018.0034-5288http://hdl.handle.net/11449/18651210.1016/j.rvsc.201.8.10.004WOS:000451937600006Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengResearch In Veterinary Scienceinfo:eu-repo/semantics/openAccess2021-10-23T19:28:25Zoai:repositorio.unesp.br:11449/186512Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T19:28:25Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
spellingShingle |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs Cerqueira, Juliana Aparecida [UNESP] creatine kinase aspartate aminotransferase myoglobin cardiac troponin I lactate heart rate |
title_short |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title_full |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title_fullStr |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title_full_unstemmed |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
title_sort |
Intense exercise and endurance-training program influence serum kinetics of muscle and cardiac biomarkers in dogs |
author |
Cerqueira, Juliana Aparecida [UNESP] |
author_facet |
Cerqueira, Juliana Aparecida [UNESP] Zamora Restan, Wilmer Alejandro [UNESP] Fonseca, Mayara Goncalves [UNESP] Catananti, Lucas Azevedo [UNESP] Mendes de Almeida, Maria Luiza [UNESP] Feringer Junior, Walter Heinz [UNESP] Pereira, Gener Tadeu [UNESP] Carciofi, Aulus Cavalieri [UNESP] Ferraz, Guilherme de Camargo [UNESP] |
author_role |
author |
author2 |
Zamora Restan, Wilmer Alejandro [UNESP] Fonseca, Mayara Goncalves [UNESP] Catananti, Lucas Azevedo [UNESP] Mendes de Almeida, Maria Luiza [UNESP] Feringer Junior, Walter Heinz [UNESP] Pereira, Gener Tadeu [UNESP] Carciofi, Aulus Cavalieri [UNESP] Ferraz, Guilherme de Camargo [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Cerqueira, Juliana Aparecida [UNESP] Zamora Restan, Wilmer Alejandro [UNESP] Fonseca, Mayara Goncalves [UNESP] Catananti, Lucas Azevedo [UNESP] Mendes de Almeida, Maria Luiza [UNESP] Feringer Junior, Walter Heinz [UNESP] Pereira, Gener Tadeu [UNESP] Carciofi, Aulus Cavalieri [UNESP] Ferraz, Guilherme de Camargo [UNESP] |
dc.subject.por.fl_str_mv |
creatine kinase aspartate aminotransferase myoglobin cardiac troponin I lactate heart rate |
topic |
creatine kinase aspartate aminotransferase myoglobin cardiac troponin I lactate heart rate |
description |
Few data exist on the physiological consequences of an incremental exercise test (IET) and training in dogs. Here we evaluated the effect of an endurance-training program (ETP) on the kinetics of the serum biomarkers: creatine kinase (CK), aspartate aminotransferase (AST), myoglobin, cardiac troponin I (cTnI), and creatine kinase isoenzyme MB (CK-MB). Eighteen Beagle dogs were assigned to three groups: sedentary (S), untrained (U), and trained (T). The dogs from the groups T and U underwent IET, and their lactate threshold (LT) was determined. The LT and velocity corresponding to the LT (VLT) was determined by visual inspection. The VLT was utilized to determine the training intensity level. Thus, the dogs from group T underwent an eight-week aerobic conditioning program with the intensity training set to 70-80% of the VLT. Next, dogs from the groups T and U have submitted to IET again. The group S did not undergo IETs or training. The maximal velocity (Vmax) at which the dog achieves in the IET and heart rate were determined. For biomarkers, venous blood samples were collected before the experimental procedure (baseline) and before and 1, 6, 12, 24, 48, and 72 h after the IETs. VLT and Vmax increased in group T (P < .05), indicating an improvement in dogs' aerobic and anaerobic fitness. CK and AST rose (P < .05), peaking 6 h after both IETs and returning to baseline levels after 12-24 h. Levels of cTnI and myoglobin were unaltered. CK-MB peaked 1 h after the IETs and returned to baseline levels after 12 h (P < .05). We concluded that ETP improved the aerobic capacity of the dogs without any skeletal or cardiac muscle injury. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-01 2019-10-05T04:10:17Z 2019-10-05T04:10:17Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.rvsc.201.8.10.004 Research In Veterinary Science. Oxford: Elsevier Sci Ltd, v. 121, p. 31-39, 2018. 0034-5288 http://hdl.handle.net/11449/186512 10.1016/j.rvsc.201.8.10.004 WOS:000451937600006 |
url |
http://dx.doi.org/10.1016/j.rvsc.201.8.10.004 http://hdl.handle.net/11449/186512 |
identifier_str_mv |
Research In Veterinary Science. Oxford: Elsevier Sci Ltd, v. 121, p. 31-39, 2018. 0034-5288 10.1016/j.rvsc.201.8.10.004 WOS:000451937600006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Research In Veterinary Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
31-39 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964915963789312 |