The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/209616 |
Resumo: | The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spennatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose. |
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Repositório Institucional da UNESP |
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The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase InhibitorGonadalToxicSpermatogenesisThe study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spennatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose.Univ Sao Paulo FMVZ USP, Sch Vet Med & Anim Sci, Dept Surg, Av Prof Dr Orlando Marques de Paiva 87, BR-05508270 Sao Paulo, SP, BrazilUninga Dept Med Vet, Fac Ingn, Rod PR 317,6114 Parque Ind Duzentos, BR-87035510 Maringa, PR, BrazilUniv State Sao Paulo FCAV UNESP, Dept Anim Morphol & Physiol, Via Acesso Prof Paulo Donato Castellane S-N, BR-14884900 Jaboticabal, SP, BrazilUniv Calif Davis, Dept Anim Sci, 1 Shields Ave, Davis, CA 95616 USAUniv State Sao Paulo FCAV UNESP, Dept Anim Morphol & Physiol, Via Acesso Prof Paulo Donato Castellane S-N, BR-14884900 Jaboticabal, SP, BrazilSoc Chilena AnatomiaUniversidade de São Paulo (USP)Uninga Dept Med VetUniversidade Estadual Paulista (Unesp)Univ Calif DavisSimoes, Luciana SennaCastro Sasahara, Tais Harumi deFavaron, Phelipe OliveiraLeal, Leonardo MartinsOliveira, Fabricio Singaretti de [UNESP]Fratini, PaulaBerger, TrishFernandes Machado, Marcia Rita [UNESP]Miglino, Maria Angelica2021-06-25T12:24:02Z2021-06-25T12:24:02Z2020-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1525-1527International Journal Of Morphology. Temuco: Soc Chilena Anatomia, v. 38, n. 6, p. 1525-1527, 2020.0717-9502http://hdl.handle.net/11449/209616WOS:000585776700001Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal Of Morphologyinfo:eu-repo/semantics/openAccess2024-06-06T18:42:28Zoai:repositorio.unesp.br:11449/209616Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:35:02.381475Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor |
title |
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor |
spellingShingle |
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor Simoes, Luciana Senna Gonadal Toxic Spermatogenesis |
title_short |
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor |
title_full |
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor |
title_fullStr |
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor |
title_full_unstemmed |
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor |
title_sort |
The Morphology of Paca (Cuniculus paca) Testis with High Dose of Letrozole an Aromatase Inhibitor |
author |
Simoes, Luciana Senna |
author_facet |
Simoes, Luciana Senna Castro Sasahara, Tais Harumi de Favaron, Phelipe Oliveira Leal, Leonardo Martins Oliveira, Fabricio Singaretti de [UNESP] Fratini, Paula Berger, Trish Fernandes Machado, Marcia Rita [UNESP] Miglino, Maria Angelica |
author_role |
author |
author2 |
Castro Sasahara, Tais Harumi de Favaron, Phelipe Oliveira Leal, Leonardo Martins Oliveira, Fabricio Singaretti de [UNESP] Fratini, Paula Berger, Trish Fernandes Machado, Marcia Rita [UNESP] Miglino, Maria Angelica |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Uninga Dept Med Vet Universidade Estadual Paulista (Unesp) Univ Calif Davis |
dc.contributor.author.fl_str_mv |
Simoes, Luciana Senna Castro Sasahara, Tais Harumi de Favaron, Phelipe Oliveira Leal, Leonardo Martins Oliveira, Fabricio Singaretti de [UNESP] Fratini, Paula Berger, Trish Fernandes Machado, Marcia Rita [UNESP] Miglino, Maria Angelica |
dc.subject.por.fl_str_mv |
Gonadal Toxic Spermatogenesis |
topic |
Gonadal Toxic Spermatogenesis |
description |
The study reported the influence of the high and acute dose of Letrozole on the testis morphology in paca (Cuniculus paca), an aromatase inhibitor that reduces the endogenous estrogen, the essential hormone for spennatogenesis. Morphological changes were observed in seminiferous epithelium with germ cells with apoptotic characteristics and presence of vacuoles and nuclei in pycnose. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-01 2021-06-25T12:24:02Z 2021-06-25T12:24:02Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
International Journal Of Morphology. Temuco: Soc Chilena Anatomia, v. 38, n. 6, p. 1525-1527, 2020. 0717-9502 http://hdl.handle.net/11449/209616 WOS:000585776700001 |
identifier_str_mv |
International Journal Of Morphology. Temuco: Soc Chilena Anatomia, v. 38, n. 6, p. 1525-1527, 2020. 0717-9502 WOS:000585776700001 |
url |
http://hdl.handle.net/11449/209616 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Journal Of Morphology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1525-1527 |
dc.publisher.none.fl_str_mv |
Soc Chilena Anatomia |
publisher.none.fl_str_mv |
Soc Chilena Anatomia |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129532149891072 |