Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease

Detalhes bibliográficos
Autor(a) principal: Milhan, Noala Vicensoto Moreira
Data de Publicação: 2014
Outros Autores: Forte, Lilibeth Ferraz De Brito Penna, Vasconcelos, Luana Marotta Reis De, Balducci, Ivan, Carvalho, Yasmin Rodarte
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/1677-3225v13n1a10
http://hdl.handle.net/11449/110012
Resumo: AIM: To evaluate the influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease induced in rats.METHODS: Forty rats were bilaterally ovariectomized and 40 were submitted to sham ovariectomy. Periodontal disease was induced in the mandibular left first molar and the maxillary left first molar was extracted from half of the rats. The rats were randomly euthanized at 3, 7, 14 and 30 days post periodontal disease induction. Serial sections were obtained from the furcation area and stained for histological and histomorphometric analysis. The results of the histomorphometric analysis were statistically analyzed by ANOVA and Tukey tests.RESULTS: The results demonstrated statistically significant differences in the percentage of bone tissue when the variables presence or absence of estrogen (p=0.020) and time of euthanasia (p=0.002) were evaluated. However, the extraction procedure did not significantly affect the percentage of bone tissue (p=0.598).CONCLUSIONS : The bone loss resulting from periodontal disease is increased by estrogen deficiency and varies according to the time course of periodontitis. In contrast, masticatory force does not seem to interfere in bone loss derived from periodontal disease.
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spelling Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal diseaseovariectomyperiodontal diseasesAIM: To evaluate the influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease induced in rats.METHODS: Forty rats were bilaterally ovariectomized and 40 were submitted to sham ovariectomy. Periodontal disease was induced in the mandibular left first molar and the maxillary left first molar was extracted from half of the rats. The rats were randomly euthanized at 3, 7, 14 and 30 days post periodontal disease induction. Serial sections were obtained from the furcation area and stained for histological and histomorphometric analysis. The results of the histomorphometric analysis were statistically analyzed by ANOVA and Tukey tests.RESULTS: The results demonstrated statistically significant differences in the percentage of bone tissue when the variables presence or absence of estrogen (p=0.020) and time of euthanasia (p=0.002) were evaluated. However, the extraction procedure did not significantly affect the percentage of bone tissue (p=0.598).CONCLUSIONS : The bone loss resulting from periodontal disease is increased by estrogen deficiency and varies according to the time course of periodontitis. In contrast, masticatory force does not seem to interfere in bone loss derived from periodontal disease.Universidade Estadual Paulista School of Dentistry of São José dos Campos Department of Biosciences and Original DiagnosisUniversidade Estadual Paulista School of Dentistry of São José dos Campos Department of Restorative DentistryUniversidade Estadual Paulista School of Dentistry of São José dos Campos Department of Biosciences and Original DiagnosisUniversidade Estadual Paulista School of Dentistry of São José dos Campos Department of Restorative DentistryUNICAMP, Faculdade de Odontologia de PiracicabaUniversidade Estadual Paulista (Unesp)Milhan, Noala Vicensoto MoreiraForte, Lilibeth Ferraz De Brito PennaVasconcelos, Luana Marotta Reis DeBalducci, IvanCarvalho, Yasmin Rodarte2014-10-01T13:08:45Z2014-10-01T13:08:45Z2014-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article47-52application/pdfhttp://dx.doi.org/10.1590/1677-3225v13n1a10Brazilian Journal of Oral Sciences. Faculdade de Odontologia de Piracicaba - UNICAMP, v. 13, n. 1, p. 47-52, 2014.1677-3225http://hdl.handle.net/11449/11001210.1590/1677-3225v13n1a10S1677-32252014000100047S1677-32252014000100047.pdf6967369119792151SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Oral Sciences0,131info:eu-repo/semantics/openAccess2023-12-26T06:14:49Zoai:repositorio.unesp.br:11449/110012Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-26T06:14:49Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease
title Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease
spellingShingle Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease
Milhan, Noala Vicensoto Moreira
ovariectomy
periodontal diseases
title_short Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease
title_full Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease
title_fullStr Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease
title_full_unstemmed Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease
title_sort Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease
author Milhan, Noala Vicensoto Moreira
author_facet Milhan, Noala Vicensoto Moreira
Forte, Lilibeth Ferraz De Brito Penna
Vasconcelos, Luana Marotta Reis De
Balducci, Ivan
Carvalho, Yasmin Rodarte
author_role author
author2 Forte, Lilibeth Ferraz De Brito Penna
Vasconcelos, Luana Marotta Reis De
Balducci, Ivan
Carvalho, Yasmin Rodarte
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Milhan, Noala Vicensoto Moreira
Forte, Lilibeth Ferraz De Brito Penna
Vasconcelos, Luana Marotta Reis De
Balducci, Ivan
Carvalho, Yasmin Rodarte
dc.subject.por.fl_str_mv ovariectomy
periodontal diseases
topic ovariectomy
periodontal diseases
description AIM: To evaluate the influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease induced in rats.METHODS: Forty rats were bilaterally ovariectomized and 40 were submitted to sham ovariectomy. Periodontal disease was induced in the mandibular left first molar and the maxillary left first molar was extracted from half of the rats. The rats were randomly euthanized at 3, 7, 14 and 30 days post periodontal disease induction. Serial sections were obtained from the furcation area and stained for histological and histomorphometric analysis. The results of the histomorphometric analysis were statistically analyzed by ANOVA and Tukey tests.RESULTS: The results demonstrated statistically significant differences in the percentage of bone tissue when the variables presence or absence of estrogen (p=0.020) and time of euthanasia (p=0.002) were evaluated. However, the extraction procedure did not significantly affect the percentage of bone tissue (p=0.598).CONCLUSIONS : The bone loss resulting from periodontal disease is increased by estrogen deficiency and varies according to the time course of periodontitis. In contrast, masticatory force does not seem to interfere in bone loss derived from periodontal disease.
publishDate 2014
dc.date.none.fl_str_mv 2014-10-01T13:08:45Z
2014-10-01T13:08:45Z
2014-03-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/1677-3225v13n1a10
Brazilian Journal of Oral Sciences. Faculdade de Odontologia de Piracicaba - UNICAMP, v. 13, n. 1, p. 47-52, 2014.
1677-3225
http://hdl.handle.net/11449/110012
10.1590/1677-3225v13n1a10
S1677-32252014000100047
S1677-32252014000100047.pdf
6967369119792151
url http://dx.doi.org/10.1590/1677-3225v13n1a10
http://hdl.handle.net/11449/110012
identifier_str_mv Brazilian Journal of Oral Sciences. Faculdade de Odontologia de Piracicaba - UNICAMP, v. 13, n. 1, p. 47-52, 2014.
1677-3225
10.1590/1677-3225v13n1a10
S1677-32252014000100047
S1677-32252014000100047.pdf
6967369119792151
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Oral Sciences
0,131
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 47-52
application/pdf
dc.publisher.none.fl_str_mv UNICAMP, Faculdade de Odontologia de Piracicaba
publisher.none.fl_str_mv UNICAMP, Faculdade de Odontologia de Piracicaba
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799965408192626688

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