Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment

Detalhes bibliográficos
Autor(a) principal: Belda, Walter
Data de Publicação: 2021
Outros Autores: Domingues Passero, Luiz Felipe [UNESP], Stradioto Casolato, Ana Thereza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1155/2021/9453701
http://hdl.handle.net/11449/229751
Resumo: Sporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed.
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spelling Lymphocutaneous Sporotrichosis Refractory to First-Line TreatmentSporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed.Dermatology Department University of São Paulo Medical School Clinics HospitalLaboratory of Pathology of Infectious Diseases Medical School University of São PauloSão Paulo State University (UNESP) Institute of Biosciences, Presidente PrudenteSão Paulo State University (UNESP) Institute for Advanced Studies of Ocean, Presidente PrudenteSão Paulo State University (UNESP) Institute of Biosciences, Presidente PrudenteSão Paulo State University (UNESP) Institute for Advanced Studies of Ocean, Presidente PrudenteUniversidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)Belda, WalterDomingues Passero, Luiz Felipe [UNESP]Stradioto Casolato, Ana Thereza2022-04-29T08:35:37Z2022-04-29T08:35:37Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1155/2021/9453701Case Reports in Dermatological Medicine, v. 2021.2090-64712090-6463http://hdl.handle.net/11449/22975110.1155/2021/94537012-s2.0-85117460820Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCase Reports in Dermatological Medicineinfo:eu-repo/semantics/openAccess2022-04-29T08:35:37Zoai:repositorio.unesp.br:11449/229751Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-29T08:35:37Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
title Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
spellingShingle Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
Belda, Walter
title_short Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
title_full Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
title_fullStr Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
title_full_unstemmed Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
title_sort Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
author Belda, Walter
author_facet Belda, Walter
Domingues Passero, Luiz Felipe [UNESP]
Stradioto Casolato, Ana Thereza
author_role author
author2 Domingues Passero, Luiz Felipe [UNESP]
Stradioto Casolato, Ana Thereza
author2_role author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Belda, Walter
Domingues Passero, Luiz Felipe [UNESP]
Stradioto Casolato, Ana Thereza
description Sporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01
2022-04-29T08:35:37Z
2022-04-29T08:35:37Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1155/2021/9453701
Case Reports in Dermatological Medicine, v. 2021.
2090-6471
2090-6463
http://hdl.handle.net/11449/229751
10.1155/2021/9453701
2-s2.0-85117460820
url http://dx.doi.org/10.1155/2021/9453701
http://hdl.handle.net/11449/229751
identifier_str_mv Case Reports in Dermatological Medicine, v. 2021.
2090-6471
2090-6463
10.1155/2021/9453701
2-s2.0-85117460820
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Case Reports in Dermatological Medicine
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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