Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1155/2021/9453701 http://hdl.handle.net/11449/229751 |
Resumo: | Sporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed. |
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Lymphocutaneous Sporotrichosis Refractory to First-Line TreatmentSporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed.Dermatology Department University of São Paulo Medical School Clinics HospitalLaboratory of Pathology of Infectious Diseases Medical School University of São PauloSão Paulo State University (UNESP) Institute of Biosciences, Presidente PrudenteSão Paulo State University (UNESP) Institute for Advanced Studies of Ocean, Presidente PrudenteSão Paulo State University (UNESP) Institute of Biosciences, Presidente PrudenteSão Paulo State University (UNESP) Institute for Advanced Studies of Ocean, Presidente PrudenteUniversidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)Belda, WalterDomingues Passero, Luiz Felipe [UNESP]Stradioto Casolato, Ana Thereza2022-04-29T08:35:37Z2022-04-29T08:35:37Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1155/2021/9453701Case Reports in Dermatological Medicine, v. 2021.2090-64712090-6463http://hdl.handle.net/11449/22975110.1155/2021/94537012-s2.0-85117460820Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCase Reports in Dermatological Medicineinfo:eu-repo/semantics/openAccess2024-06-18T18:18:15Zoai:repositorio.unesp.br:11449/229751Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:10:02.134530Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
title |
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
spellingShingle |
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment Belda, Walter |
title_short |
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
title_full |
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
title_fullStr |
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
title_full_unstemmed |
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
title_sort |
Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
author |
Belda, Walter |
author_facet |
Belda, Walter Domingues Passero, Luiz Felipe [UNESP] Stradioto Casolato, Ana Thereza |
author_role |
author |
author2 |
Domingues Passero, Luiz Felipe [UNESP] Stradioto Casolato, Ana Thereza |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Belda, Walter Domingues Passero, Luiz Felipe [UNESP] Stradioto Casolato, Ana Thereza |
description |
Sporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 2022-04-29T08:35:37Z 2022-04-29T08:35:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1155/2021/9453701 Case Reports in Dermatological Medicine, v. 2021. 2090-6471 2090-6463 http://hdl.handle.net/11449/229751 10.1155/2021/9453701 2-s2.0-85117460820 |
url |
http://dx.doi.org/10.1155/2021/9453701 http://hdl.handle.net/11449/229751 |
identifier_str_mv |
Case Reports in Dermatological Medicine, v. 2021. 2090-6471 2090-6463 10.1155/2021/9453701 2-s2.0-85117460820 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Case Reports in Dermatological Medicine |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129292152864768 |