Efeito da adição de nanopartículas de hexametafosfato de sódio em dentifrícios fluoretados sobre a remineralização dentária: estudo in situ

• Autor(a) principal: Passarinho, Amanda [UNESP]
• Data de Publicação: 2016
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/155188; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2017-05-03/000880657.pdf
• topic: Esmalte dentário; Fluoretos; Fosfatos; Desmineralização do dente; Dentifrícios; Nanopartículas; Dental enamel

The aim of this study was to evaluate in situ the remineralization potential of conventional toothpaste (1100 ppm F) supplemented with nano-sized of sodium hexametaphosphate (HMPnano) in artificial caries lesions. This blind, crossover study was conducted on 4 experimental phases with each lasting 3 days, and 7 days washout. Volunteers (n = 12) palatal appliances containing 4 enamel blocks with bovine artificial caries lesion. Treatment regimens were: No F/HMP/HMPnano (Placebo); 1100 ppm F (1100F), 1100 ppm F supplemented with 0.5% HMP micrometer and nano-sized (1100F/ HMP, 1100F/HMPnano). The volunteers were instructed to brush their teeth with natural palatal devices in the oral cavity, the blocks treated with the slurry of dentifrice for 1 minute (3x/day). After each phase, the percentage of surface hardness recovery (%SHR), integrated loss of hardness subsurface (ΔKHN) and the concentration of fluoride in the enamel (F) were determined. The results were submitted to analysis of variance and Student-Newman-Keuls test (p < 0.001). The enamel surface treated with 1100F/HMPnano remineralized 68% more when treated with in relation to 1100F (p < 0,001). 1100F/HMPnano reduced ~ 33% in the body of the lesion relative to 1100F (p < 0.001). The absorption F enamel is similar between groups, except for Placebo (p < 0.001), which showed the lowest concentration. It was concluded that the addition of 0.5%HMPnano a conventional toothpaste, promoted significantly higher remineralizing effect compared to 1100 ppm F