Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1678-91992006000100003 http://hdl.handle.net/11449/68850 |
Resumo: | Scorpionism is a common problem that occurs in tropical and subtropical countries and assumes great medical-sanitary importance due to its fatal effect on sensitive individuals, being able to lead children and aged people to death. The envenomation lethal potential is responsible for the serious cardiopulmonary alterations the scorpion toxin produces in its victims. The present research evaluated the effects of Tityus serrulatus venom on dogs, using two distinct doses: a dose that simulates natural envenomation (0.4 mg/total dose), and an experimental dose (0.25 mg/kg). General clinical signs were observed at different moments after envenomation, and specific data related to the cardiopulmonary system were evaluated by systemic arterial pressure measurement, CK-MB enzymatic activity dosage, and radiographic, electrocardiographic and echocardiographic examinations. Results demonstrated that the scorpion venom, in experimental doses, was able to cause acute and reversible cardiac injury in few days, and, in the dose that simulated natural accident, it produced clinical signs of light envenomation, such as local pain, hyperesthesia, sialorrhea, vomiting, diarrhea, sneeze and prostration. |
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Clinical and cardiovascular alterations produced by scorpion envenomation in dogsCardiopulmonary alterationsDogsScorpionTityus serrulatusCanis familiarisScorpionesScorpionism is a common problem that occurs in tropical and subtropical countries and assumes great medical-sanitary importance due to its fatal effect on sensitive individuals, being able to lead children and aged people to death. The envenomation lethal potential is responsible for the serious cardiopulmonary alterations the scorpion toxin produces in its victims. The present research evaluated the effects of Tityus serrulatus venom on dogs, using two distinct doses: a dose that simulates natural envenomation (0.4 mg/total dose), and an experimental dose (0.25 mg/kg). General clinical signs were observed at different moments after envenomation, and specific data related to the cardiopulmonary system were evaluated by systemic arterial pressure measurement, CK-MB enzymatic activity dosage, and radiographic, electrocardiographic and echocardiographic examinations. Results demonstrated that the scorpion venom, in experimental doses, was able to cause acute and reversible cardiac injury in few days, and, in the dose that simulated natural accident, it produced clinical signs of light envenomation, such as local pain, hyperesthesia, sialorrhea, vomiting, diarrhea, sneeze and prostration.Department of Clinical Veterinary Medicine School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São PauloClinical Laboratory School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São PauloVeterinary Diagnostic, São PauloDepartamento de Clínica Veterinária Faculdade de Medicina Veterinária e Zootecnia UNESP, Distrito de Rubião Jr., s/n, 18.618-000, Botucatu, SPDepartment of Clinical Veterinary Medicine School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São PauloClinical Laboratory School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São PauloDepartamento de Clínica Veterinária Faculdade de Medicina Veterinária e Zootecnia UNESP, Distrito de Rubião Jr., s/n, 18.618-000, Botucatu, SPUniversidade Estadual Paulista (Unesp)Cordeiro, F. F. [UNESP]Sakate, M. [UNESP]Fernandes, V. [UNESP]Cuyumjian, P. R.2014-05-27T11:21:51Z2014-05-27T11:21:51Z2006-04-26info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article19-43application/pdfhttp://dx.doi.org/10.1590/S1678-91992006000100003Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 1, p. 19-43, 2006.1678-9199http://hdl.handle.net/11449/6885010.1590/S1678-91992006000100003S1678-91992006000100003WOS:0002462810000032-s2.0-336458884282-s2.0-33645888428.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2024-01-24T06:34:46Zoai:repositorio.unesp.br:11449/68850Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:52:18.435356Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Clinical and cardiovascular alterations produced by scorpion envenomation in dogs |
title |
Clinical and cardiovascular alterations produced by scorpion envenomation in dogs |
spellingShingle |
Clinical and cardiovascular alterations produced by scorpion envenomation in dogs Cordeiro, F. F. [UNESP] Cardiopulmonary alterations Dogs Scorpion Tityus serrulatus Canis familiaris Scorpiones |
title_short |
Clinical and cardiovascular alterations produced by scorpion envenomation in dogs |
title_full |
Clinical and cardiovascular alterations produced by scorpion envenomation in dogs |
title_fullStr |
Clinical and cardiovascular alterations produced by scorpion envenomation in dogs |
title_full_unstemmed |
Clinical and cardiovascular alterations produced by scorpion envenomation in dogs |
title_sort |
Clinical and cardiovascular alterations produced by scorpion envenomation in dogs |
author |
Cordeiro, F. F. [UNESP] |
author_facet |
Cordeiro, F. F. [UNESP] Sakate, M. [UNESP] Fernandes, V. [UNESP] Cuyumjian, P. R. |
author_role |
author |
author2 |
Sakate, M. [UNESP] Fernandes, V. [UNESP] Cuyumjian, P. R. |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Cordeiro, F. F. [UNESP] Sakate, M. [UNESP] Fernandes, V. [UNESP] Cuyumjian, P. R. |
dc.subject.por.fl_str_mv |
Cardiopulmonary alterations Dogs Scorpion Tityus serrulatus Canis familiaris Scorpiones |
topic |
Cardiopulmonary alterations Dogs Scorpion Tityus serrulatus Canis familiaris Scorpiones |
description |
Scorpionism is a common problem that occurs in tropical and subtropical countries and assumes great medical-sanitary importance due to its fatal effect on sensitive individuals, being able to lead children and aged people to death. The envenomation lethal potential is responsible for the serious cardiopulmonary alterations the scorpion toxin produces in its victims. The present research evaluated the effects of Tityus serrulatus venom on dogs, using two distinct doses: a dose that simulates natural envenomation (0.4 mg/total dose), and an experimental dose (0.25 mg/kg). General clinical signs were observed at different moments after envenomation, and specific data related to the cardiopulmonary system were evaluated by systemic arterial pressure measurement, CK-MB enzymatic activity dosage, and radiographic, electrocardiographic and echocardiographic examinations. Results demonstrated that the scorpion venom, in experimental doses, was able to cause acute and reversible cardiac injury in few days, and, in the dose that simulated natural accident, it produced clinical signs of light envenomation, such as local pain, hyperesthesia, sialorrhea, vomiting, diarrhea, sneeze and prostration. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-04-26 2014-05-27T11:21:51Z 2014-05-27T11:21:51Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1678-91992006000100003 Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 1, p. 19-43, 2006. 1678-9199 http://hdl.handle.net/11449/68850 10.1590/S1678-91992006000100003 S1678-91992006000100003 WOS:000246281000003 2-s2.0-33645888428 2-s2.0-33645888428.pdf |
url |
http://dx.doi.org/10.1590/S1678-91992006000100003 http://hdl.handle.net/11449/68850 |
identifier_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 1, p. 19-43, 2006. 1678-9199 10.1590/S1678-91992006000100003 S1678-91992006000100003 WOS:000246281000003 2-s2.0-33645888428 2-s2.0-33645888428.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases 1.782 0,573 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
19-43 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129560111218688 |