Clinical and cardiovascular alterations produced by scorpion envenomation in dogs

Detalhes bibliográficos
Autor(a) principal: Cordeiro, F. F. [UNESP]
Data de Publicação: 2006
Outros Autores: Sakate, M. [UNESP], Fernandes, V. [UNESP], Cuyumjian, P. R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1678-91992006000100003
http://hdl.handle.net/11449/68850
Resumo: Scorpionism is a common problem that occurs in tropical and subtropical countries and assumes great medical-sanitary importance due to its fatal effect on sensitive individuals, being able to lead children and aged people to death. The envenomation lethal potential is responsible for the serious cardiopulmonary alterations the scorpion toxin produces in its victims. The present research evaluated the effects of Tityus serrulatus venom on dogs, using two distinct doses: a dose that simulates natural envenomation (0.4 mg/total dose), and an experimental dose (0.25 mg/kg). General clinical signs were observed at different moments after envenomation, and specific data related to the cardiopulmonary system were evaluated by systemic arterial pressure measurement, CK-MB enzymatic activity dosage, and radiographic, electrocardiographic and echocardiographic examinations. Results demonstrated that the scorpion venom, in experimental doses, was able to cause acute and reversible cardiac injury in few days, and, in the dose that simulated natural accident, it produced clinical signs of light envenomation, such as local pain, hyperesthesia, sialorrhea, vomiting, diarrhea, sneeze and prostration.
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spelling Clinical and cardiovascular alterations produced by scorpion envenomation in dogsCardiopulmonary alterationsDogsScorpionTityus serrulatusCanis familiarisScorpionesScorpionism is a common problem that occurs in tropical and subtropical countries and assumes great medical-sanitary importance due to its fatal effect on sensitive individuals, being able to lead children and aged people to death. The envenomation lethal potential is responsible for the serious cardiopulmonary alterations the scorpion toxin produces in its victims. The present research evaluated the effects of Tityus serrulatus venom on dogs, using two distinct doses: a dose that simulates natural envenomation (0.4 mg/total dose), and an experimental dose (0.25 mg/kg). General clinical signs were observed at different moments after envenomation, and specific data related to the cardiopulmonary system were evaluated by systemic arterial pressure measurement, CK-MB enzymatic activity dosage, and radiographic, electrocardiographic and echocardiographic examinations. Results demonstrated that the scorpion venom, in experimental doses, was able to cause acute and reversible cardiac injury in few days, and, in the dose that simulated natural accident, it produced clinical signs of light envenomation, such as local pain, hyperesthesia, sialorrhea, vomiting, diarrhea, sneeze and prostration.Department of Clinical Veterinary Medicine School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São PauloClinical Laboratory School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São PauloVeterinary Diagnostic, São PauloDepartamento de Clínica Veterinária Faculdade de Medicina Veterinária e Zootecnia UNESP, Distrito de Rubião Jr., s/n, 18.618-000, Botucatu, SPDepartment of Clinical Veterinary Medicine School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São PauloClinical Laboratory School of Veterinary Medicine and Animal Husbandry São Paulo State University, Botucatu, São PauloDepartamento de Clínica Veterinária Faculdade de Medicina Veterinária e Zootecnia UNESP, Distrito de Rubião Jr., s/n, 18.618-000, Botucatu, SPUniversidade Estadual Paulista (Unesp)Cordeiro, F. F. [UNESP]Sakate, M. [UNESP]Fernandes, V. [UNESP]Cuyumjian, P. R.2014-05-27T11:21:51Z2014-05-27T11:21:51Z2006-04-26info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article19-43application/pdfhttp://dx.doi.org/10.1590/S1678-91992006000100003Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 1, p. 19-43, 2006.1678-9199http://hdl.handle.net/11449/6885010.1590/S1678-91992006000100003S1678-91992006000100003WOS:0002462810000032-s2.0-336458884282-s2.0-33645888428.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2024-01-24T06:34:46Zoai:repositorio.unesp.br:11449/68850Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:52:18.435356Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
title Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
spellingShingle Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
Cordeiro, F. F. [UNESP]
Cardiopulmonary alterations
Dogs
Scorpion
Tityus serrulatus
Canis familiaris
Scorpiones
title_short Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
title_full Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
title_fullStr Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
title_full_unstemmed Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
title_sort Clinical and cardiovascular alterations produced by scorpion envenomation in dogs
author Cordeiro, F. F. [UNESP]
author_facet Cordeiro, F. F. [UNESP]
Sakate, M. [UNESP]
Fernandes, V. [UNESP]
Cuyumjian, P. R.
author_role author
author2 Sakate, M. [UNESP]
Fernandes, V. [UNESP]
Cuyumjian, P. R.
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Cordeiro, F. F. [UNESP]
Sakate, M. [UNESP]
Fernandes, V. [UNESP]
Cuyumjian, P. R.
dc.subject.por.fl_str_mv Cardiopulmonary alterations
Dogs
Scorpion
Tityus serrulatus
Canis familiaris
Scorpiones
topic Cardiopulmonary alterations
Dogs
Scorpion
Tityus serrulatus
Canis familiaris
Scorpiones
description Scorpionism is a common problem that occurs in tropical and subtropical countries and assumes great medical-sanitary importance due to its fatal effect on sensitive individuals, being able to lead children and aged people to death. The envenomation lethal potential is responsible for the serious cardiopulmonary alterations the scorpion toxin produces in its victims. The present research evaluated the effects of Tityus serrulatus venom on dogs, using two distinct doses: a dose that simulates natural envenomation (0.4 mg/total dose), and an experimental dose (0.25 mg/kg). General clinical signs were observed at different moments after envenomation, and specific data related to the cardiopulmonary system were evaluated by systemic arterial pressure measurement, CK-MB enzymatic activity dosage, and radiographic, electrocardiographic and echocardiographic examinations. Results demonstrated that the scorpion venom, in experimental doses, was able to cause acute and reversible cardiac injury in few days, and, in the dose that simulated natural accident, it produced clinical signs of light envenomation, such as local pain, hyperesthesia, sialorrhea, vomiting, diarrhea, sneeze and prostration.
publishDate 2006
dc.date.none.fl_str_mv 2006-04-26
2014-05-27T11:21:51Z
2014-05-27T11:21:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1678-91992006000100003
Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 1, p. 19-43, 2006.
1678-9199
http://hdl.handle.net/11449/68850
10.1590/S1678-91992006000100003
S1678-91992006000100003
WOS:000246281000003
2-s2.0-33645888428
2-s2.0-33645888428.pdf
url http://dx.doi.org/10.1590/S1678-91992006000100003
http://hdl.handle.net/11449/68850
identifier_str_mv Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 12, n. 1, p. 19-43, 2006.
1678-9199
10.1590/S1678-91992006000100003
S1678-91992006000100003
WOS:000246281000003
2-s2.0-33645888428
2-s2.0-33645888428.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Venomous Animals and Toxins Including Tropical Diseases
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0,573
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 19-43
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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