Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GO

Detalhes bibliográficos
Autor(a) principal: Moraes, Dayane
Data de Publicação: 2014
Outros Autores: Braoios, Alexandre, Alves, Janio Leal Borges, Costa, Rafael Menezes Da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.5935/1676-2444.20140015
http://hdl.handle.net/11449/114363
Resumo: Introduction: Urinary tract infections (UTIs) affect people worldwide. Escherichia coli is the main agent of UTI, however the etiology may vary according to the age and sex of the patient. Regional variations in the prevalence and antimicrobial resistance should be considered for therapy choice. Objectives: This study aimed to conduct a survey on the main agents of UTI, and assess the resistance of these microorganisms, during the period of March 2010 to June 2012 in the city of Jataí-GO. Method: A retrospective cross-sectional study were performed, collecting data on the prevalence of uropathogens and their sensitivity profiles which were evaluated by disk diffusion method. Results: During this period, 2,181 urine cultures were evaluated, of which 510 (23.4%) were positive, predominantly female (81.4%) and aged between 21 and 64 years old (59.7%). The most frequently isolated microorganism was E. coli (61%), followed by Staphylococcus saprophyticus (9.4%), and Proteus (9.4%). The prevalence of these bacteria according to the patient sex has suffered a statistically significant change (p < 0.05). It was possible to detect high resistance rate of E. coli to some antibiotics of choice for UTI treatment, such as ampicillin (57.9 %), pipemidic acid (50.5 %), nalidixic acid (48.6 %), and trimethoprim-sulfamethoxazole (44.8%). Conclusion: These data demonstrate the need to know the reality of each region in order to establish an appropriate empirical therapy, when it is not possible to perform culture and antimicrobial susceptibility testing.
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spelling Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GOPrevalência de uropatógenos e perfil de sensibilidade aos antimicrobianos em pacientes ambulatoriais de Jataí-GOinfecção urináriaEscherichia coliresistência aos antimicrobianosurinary tract infectionEscherichia coliantimicrobial resistanceIntroduction: Urinary tract infections (UTIs) affect people worldwide. Escherichia coli is the main agent of UTI, however the etiology may vary according to the age and sex of the patient. Regional variations in the prevalence and antimicrobial resistance should be considered for therapy choice. Objectives: This study aimed to conduct a survey on the main agents of UTI, and assess the resistance of these microorganisms, during the period of March 2010 to June 2012 in the city of Jataí-GO. Method: A retrospective cross-sectional study were performed, collecting data on the prevalence of uropathogens and their sensitivity profiles which were evaluated by disk diffusion method. Results: During this period, 2,181 urine cultures were evaluated, of which 510 (23.4%) were positive, predominantly female (81.4%) and aged between 21 and 64 years old (59.7%). The most frequently isolated microorganism was E. coli (61%), followed by Staphylococcus saprophyticus (9.4%), and Proteus (9.4%). The prevalence of these bacteria according to the patient sex has suffered a statistically significant change (p < 0.05). It was possible to detect high resistance rate of E. coli to some antibiotics of choice for UTI treatment, such as ampicillin (57.9 %), pipemidic acid (50.5 %), nalidixic acid (48.6 %), and trimethoprim-sulfamethoxazole (44.8%). Conclusion: These data demonstrate the need to know the reality of each region in order to establish an appropriate empirical therapy, when it is not possible to perform culture and antimicrobial susceptibility testing.Introdução: Infecções do trato urinário (ITU) afetam pessoas em todo o mundo. Escherichia coli é o principal agente de ITU, no entanto a etiologia pode variar de acordo com o sexo e a idade do paciente. Variações regionais quanto à prevalência e à resistência aos antimicrobianos devem ser consideradas para a escolha terapêutica. Objetivos: Este trabalho teve por objetivo realizar um levantamento sobre os principais agentes de ITU e avaliar o perfil de resistência desses microrganismos no período de março de 2010 a junho de 2012, na cidade de Jataí-GO. Método: Estudo retrospectivo de corte transversal realizado por meio de coleta de dados sobre a prevalência de uropatógenos e seus perfis de sensibilidade avaliados pelo método da difusão. Resultados: Neste período, foram realizadas 2.181 uroculturas, das quais 510 (23,4%) apresentaram resultado positivo, sendo predominantemente do sexo feminino (81,4%) e com idade entre 21 e 64 anos de idade (59,7%). O microrganismo mais frequentemente isolado foi E. coli (61%), seguido de Staphylococcus saprophyticus (9,4%) e Proteus (9,4%). A prevalência dessas bactérias, de acordo com o sexo do paciente, sofreu variação estatisticamente significativa (p < 0,05). Foi possível constatar elevada taxa de resistência de E. coli para alguns antimicrobianos de primeira escolha para tratamento de ITU, como ampicilina (57,9%), ácido pipemídico (50,5%), ácido nalidíxico (48,6%) e sulfazotrim (44,8%). Conclusão: Esses dados demonstram a necessidade de se conhecer a realidade de cada região a fim de se estabelecer uma terapia empírica adequada, quando não for possível a realização da cultura e do antibiograma.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Federal de GoiásUniversidade Estadual PaulistaUFGUniversidade Estadual de MaringáUniversidade de São PauloUniversidade Estadual PaulistaSociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de CitopatologiaUniversidade Federal de Goiás (UFG)Universidade Estadual Paulista (Unesp)UFGUniversidade Estadual de Maringá (UEM)Universidade de São Paulo (USP)Moraes, DayaneBraoios, AlexandreAlves, Janio Leal BorgesCosta, Rafael Menezes Da2015-02-02T12:39:28Z2015-02-02T12:39:28Z2014-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article200-204application/pdfhttp://dx.doi.org/10.5935/1676-2444.20140015Jornal Brasileiro de Patologia e Medicina Laboratorial. Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, v. 50, n. 3, p. 200-204, 2014.1676-2444http://hdl.handle.net/11449/11436310.5935/1676-2444.20140015S1676-24442014000300200S1676-24442014000300200.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJornal Brasileiro de Patologia e Medicina Laboratorial0,143info:eu-repo/semantics/openAccess2023-12-28T06:14:29Zoai:repositorio.unesp.br:11449/114363Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:29:10.833377Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GO
Prevalência de uropatógenos e perfil de sensibilidade aos antimicrobianos em pacientes ambulatoriais de Jataí-GO
title Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GO
spellingShingle Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GO
Moraes, Dayane
infecção urinária
Escherichia coli
resistência aos antimicrobianos
urinary tract infection
Escherichia coli
antimicrobial resistance
title_short Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GO
title_full Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GO
title_fullStr Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GO
title_full_unstemmed Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GO
title_sort Prevalence of uropathogens and antimicrobial susceptibility profile in outpatient from Jataí-GO
author Moraes, Dayane
author_facet Moraes, Dayane
Braoios, Alexandre
Alves, Janio Leal Borges
Costa, Rafael Menezes Da
author_role author
author2 Braoios, Alexandre
Alves, Janio Leal Borges
Costa, Rafael Menezes Da
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de Goiás (UFG)
Universidade Estadual Paulista (Unesp)
UFG
Universidade Estadual de Maringá (UEM)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Moraes, Dayane
Braoios, Alexandre
Alves, Janio Leal Borges
Costa, Rafael Menezes Da
dc.subject.por.fl_str_mv infecção urinária
Escherichia coli
resistência aos antimicrobianos
urinary tract infection
Escherichia coli
antimicrobial resistance
topic infecção urinária
Escherichia coli
resistência aos antimicrobianos
urinary tract infection
Escherichia coli
antimicrobial resistance
description Introduction: Urinary tract infections (UTIs) affect people worldwide. Escherichia coli is the main agent of UTI, however the etiology may vary according to the age and sex of the patient. Regional variations in the prevalence and antimicrobial resistance should be considered for therapy choice. Objectives: This study aimed to conduct a survey on the main agents of UTI, and assess the resistance of these microorganisms, during the period of March 2010 to June 2012 in the city of Jataí-GO. Method: A retrospective cross-sectional study were performed, collecting data on the prevalence of uropathogens and their sensitivity profiles which were evaluated by disk diffusion method. Results: During this period, 2,181 urine cultures were evaluated, of which 510 (23.4%) were positive, predominantly female (81.4%) and aged between 21 and 64 years old (59.7%). The most frequently isolated microorganism was E. coli (61%), followed by Staphylococcus saprophyticus (9.4%), and Proteus (9.4%). The prevalence of these bacteria according to the patient sex has suffered a statistically significant change (p < 0.05). It was possible to detect high resistance rate of E. coli to some antibiotics of choice for UTI treatment, such as ampicillin (57.9 %), pipemidic acid (50.5 %), nalidixic acid (48.6 %), and trimethoprim-sulfamethoxazole (44.8%). Conclusion: These data demonstrate the need to know the reality of each region in order to establish an appropriate empirical therapy, when it is not possible to perform culture and antimicrobial susceptibility testing.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-01
2015-02-02T12:39:28Z
2015-02-02T12:39:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.5935/1676-2444.20140015
Jornal Brasileiro de Patologia e Medicina Laboratorial. Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, v. 50, n. 3, p. 200-204, 2014.
1676-2444
http://hdl.handle.net/11449/114363
10.5935/1676-2444.20140015
S1676-24442014000300200
S1676-24442014000300200.pdf
url http://dx.doi.org/10.5935/1676-2444.20140015
http://hdl.handle.net/11449/114363
identifier_str_mv Jornal Brasileiro de Patologia e Medicina Laboratorial. Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, v. 50, n. 3, p. 200-204, 2014.
1676-2444
10.5935/1676-2444.20140015
S1676-24442014000300200
S1676-24442014000300200.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Jornal Brasileiro de Patologia e Medicina Laboratorial
0,143
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv 200-204
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia
publisher.none.fl_str_mv Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
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