Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleen

Detalhes bibliográficos
Autor(a) principal: Eto, S. F. [UNESP]
Data de Publicação: 2018
Outros Autores: Fernandes, D. C. [UNESP], Rosolem, M. C. [UNESP], Marinho-Neto, F. A. [UNESP], Pizauro, J. M. [UNESP], Salvador, R., Moraes, J. R. E. [UNESP], Moraes, F. R. [UNESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/1678-4162-9063
http://hdl.handle.net/11449/160258
Resumo: This work aimed to evaluate the role of the spleen in storage and reactivation of the memory B cells, represented by IgM positive cells and the systemic production of sheep antibodies anti-red cell in Nile tilapia (Oreochromis niloticus). Two groups were established: the memory group, containing fish previously immunized with a 2,5% sheep anti-red cell, to generate the immune memory; and the naive group, containing fish that received a 0,65% saline solution. After 32 days, both groups were subjected to a new dose of the same antigen at the same concentration, volume, and inoculation via. The memory clones reactivation was correlated to the increase of the IgM positive cells in the spleen in the memory group at 0 day. The memory group showed an increase in the absolute number of lymphocytes at 21 days and an increase in the antibodies at 14 days after inoculation when compared to the naive group. The results suggest that the spleen may be a storage and reactivation place of memory B cells in Nile tilapia.
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spelling Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleenteleostimmunologyimmunoglobulin MvaccineThis work aimed to evaluate the role of the spleen in storage and reactivation of the memory B cells, represented by IgM positive cells and the systemic production of sheep antibodies anti-red cell in Nile tilapia (Oreochromis niloticus). Two groups were established: the memory group, containing fish previously immunized with a 2,5% sheep anti-red cell, to generate the immune memory; and the naive group, containing fish that received a 0,65% saline solution. After 32 days, both groups were subjected to a new dose of the same antigen at the same concentration, volume, and inoculation via. The memory clones reactivation was correlated to the increase of the IgM positive cells in the spleen in the memory group at 0 day. The memory group showed an increase in the absolute number of lymphocytes at 21 days and an increase in the antibodies at 14 days after inoculation when compared to the naive group. The results suggest that the spleen may be a storage and reactivation place of memory B cells in Nile tilapia.Univ Estadual Paulista, Jaboticabal, SP, BrazilUniv Estadual Paulista, Araraquara, SP, BrazilUniv Estadual Norte Parana, Bandeirantes, PR, BrazilUniv Estadual Paulista, Jaboticabal, SP, BrazilUniv Estadual Paulista, Araraquara, SP, BrazilArquivo Brasileiro Medicina Veterinaria ZootecniaUniversidade Estadual Paulista (Unesp)Univ Estadual Norte ParanaEto, S. F. [UNESP]Fernandes, D. C. [UNESP]Rosolem, M. C. [UNESP]Marinho-Neto, F. A. [UNESP]Pizauro, J. M. [UNESP]Salvador, R.Moraes, J. R. E. [UNESP]Moraes, F. R. [UNESP]2018-11-26T16:01:09Z2018-11-26T16:01:09Z2018-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article205-212application/pdfhttp://dx.doi.org/10.1590/1678-4162-9063Arquivo Brasileiro De Medicina Veterinaria E Zootecnia. Minas Gerais: Arquivo Brasileiro Medicina Veterinaria Zootecnia, v. 70, n. 1, p. 205-212, 2018.0102-0935http://hdl.handle.net/11449/16025810.1590/1678-4162-9063S0102-09352018000100205WOS:000431307800029S0102-09352018000100205.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporArquivo Brasileiro De Medicina Veterinaria E Zootecnia0,248info:eu-repo/semantics/openAccess2023-10-28T06:12:28Zoai:repositorio.unesp.br:11449/160258Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-28T06:12:28Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleen
title Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleen
spellingShingle Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleen
Eto, S. F. [UNESP]
teleost
immunology
immunoglobulin M
vaccine
title_short Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleen
title_full Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleen
title_fullStr Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleen
title_full_unstemmed Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleen
title_sort Activation of memory cells in the antibody production and the expression of IgM positive cells in Nile tilapia spleen
author Eto, S. F. [UNESP]
author_facet Eto, S. F. [UNESP]
Fernandes, D. C. [UNESP]
Rosolem, M. C. [UNESP]
Marinho-Neto, F. A. [UNESP]
Pizauro, J. M. [UNESP]
Salvador, R.
Moraes, J. R. E. [UNESP]
Moraes, F. R. [UNESP]
author_role author
author2 Fernandes, D. C. [UNESP]
Rosolem, M. C. [UNESP]
Marinho-Neto, F. A. [UNESP]
Pizauro, J. M. [UNESP]
Salvador, R.
Moraes, J. R. E. [UNESP]
Moraes, F. R. [UNESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Univ Estadual Norte Parana
dc.contributor.author.fl_str_mv Eto, S. F. [UNESP]
Fernandes, D. C. [UNESP]
Rosolem, M. C. [UNESP]
Marinho-Neto, F. A. [UNESP]
Pizauro, J. M. [UNESP]
Salvador, R.
Moraes, J. R. E. [UNESP]
Moraes, F. R. [UNESP]
dc.subject.por.fl_str_mv teleost
immunology
immunoglobulin M
vaccine
topic teleost
immunology
immunoglobulin M
vaccine
description This work aimed to evaluate the role of the spleen in storage and reactivation of the memory B cells, represented by IgM positive cells and the systemic production of sheep antibodies anti-red cell in Nile tilapia (Oreochromis niloticus). Two groups were established: the memory group, containing fish previously immunized with a 2,5% sheep anti-red cell, to generate the immune memory; and the naive group, containing fish that received a 0,65% saline solution. After 32 days, both groups were subjected to a new dose of the same antigen at the same concentration, volume, and inoculation via. The memory clones reactivation was correlated to the increase of the IgM positive cells in the spleen in the memory group at 0 day. The memory group showed an increase in the absolute number of lymphocytes at 21 days and an increase in the antibodies at 14 days after inoculation when compared to the naive group. The results suggest that the spleen may be a storage and reactivation place of memory B cells in Nile tilapia.
publishDate 2018
dc.date.none.fl_str_mv 2018-11-26T16:01:09Z
2018-11-26T16:01:09Z
2018-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/1678-4162-9063
Arquivo Brasileiro De Medicina Veterinaria E Zootecnia. Minas Gerais: Arquivo Brasileiro Medicina Veterinaria Zootecnia, v. 70, n. 1, p. 205-212, 2018.
0102-0935
http://hdl.handle.net/11449/160258
10.1590/1678-4162-9063
S0102-09352018000100205
WOS:000431307800029
S0102-09352018000100205.pdf
url http://dx.doi.org/10.1590/1678-4162-9063
http://hdl.handle.net/11449/160258
identifier_str_mv Arquivo Brasileiro De Medicina Veterinaria E Zootecnia. Minas Gerais: Arquivo Brasileiro Medicina Veterinaria Zootecnia, v. 70, n. 1, p. 205-212, 2018.
0102-0935
10.1590/1678-4162-9063
S0102-09352018000100205
WOS:000431307800029
S0102-09352018000100205.pdf
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Arquivo Brasileiro De Medicina Veterinaria E Zootecnia
0,248
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 205-212
application/pdf
dc.publisher.none.fl_str_mv Arquivo Brasileiro Medicina Veterinaria Zootecnia
publisher.none.fl_str_mv Arquivo Brasileiro Medicina Veterinaria Zootecnia
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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