Uso de plasma rico em plaquetas em úlceras de córnea em cães

• Autor(a) principal: Merlini, Natalie B. [UNESP]
• Data de Publicação: 2014
• Outros Autores: Fonzar, Joice Furtado [UNESP], Perches, Cíntia Sesso [UNESP], Sereno, Maria Guadalupe [UNESP], Souza, Vivian Lima de [UNESP], Rodas, Natália Rodrigues [UNESP], Padovan, Carlos Roberto [UNESP], Brandão, Cláudia Valéria Seullner [UNESP], Ranzani, José Joaquim Titton [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0102-09352014000601742&lng=en&nrm=iso&tlng=en; http://hdl.handle.net/11449/137107
• topic: Dogs; Epithelial defect; Growth factors; PRP; Cão; Defeito epitelial; Fatores de crescimento; PRP

This study aims to clinically and macroscopically evaluate the adjuvant therapy with platelet-rich plasma in the form of eyedrops or clot, for corneal ulcers in dogs treated at the Veterinary Ophthalmology Service. We analyzed 20 eyes diagnosed with ulcerative keratitis, divided into two experimental groups. The eyedrop group (GC) was composed of eyes treated topically with eyedrops of autologous plateletrich plasma (PRP), and the clot group (GT) was composed of eyes treated with a platelet-rich clot and covered with a third eyelid for retention of the clot. The groups were evaluated by clinical and macroscopic analysis and by the analysis of epithelial defect reduction, at different times, at three, five, ten, 15 and 30 days, except for the third day in GT. The coverage of the third eyelid was removed on the fifth day. In both groups the inflammation signs reduced, there was an improvement in ocular sensibility and proper repair of epithelial defect. All GT eyes and 70% GC eyes showed complete healing on the fifth day, the remainder of GC completed healing on the tenth day. PRP in the form of eyedrops and clot is an excellent adjuvant therapy to be instituted in the clinical treatment for corneal ulcer in dogs, because it decreases the inflammatory signs and the ocular pain and it potentially assists in healing epithelial defects.