Antiulcerogenic Compounds Isolated from Medicinal Plants

Detalhes bibliográficos
Autor(a) principal: Beserra, Fernando Pereira [UNESP]
Data de Publicação: 2016
Outros Autores: Rozza, Ariane Leite [UNESP], Vieira, Ana Júlia [UNESP], Sérgio Gushiken, Lucas Fernando [UNESP], Pellizzon, Cláudia Helena [UNESP]
Tipo de documento: Artigo de conferência
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/B978-0-444-63603-4.00006-1
http://hdl.handle.net/11449/178114
Resumo: The gastric mucosa is continuously exposed to damaging agents that are involved in the pathogenesis of gastric ulcers, the most common chronic gastrointestinal disease. Common habits such as stress, coffee ingestion, tobacco, alcohol, and nonsteroidal antiinflammatory drugs' consumption contribute to the physiopathology of gastric ulcers. There is an ongoing search to discover novel bioactive gastroprotective and ulcer-healing compounds derived from medicinal plants. Among antiulcer studies using natural products, those focused on isolated compounds have brought promising results, which is important for developing new drugs against gastric ulcers. In this manuscript, we review the published antiulcer studies dedicated to isolated compounds, highlighting the chemical structure and mechanisms of action of each compound and trying to elucidate a structure-activity relationship for the tested compounds.
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spelling Antiulcerogenic Compounds Isolated from Medicinal Plantsalkaloidsgastric ulcerisolated compoundsphenolic compoundssaponinsterpenesThe gastric mucosa is continuously exposed to damaging agents that are involved in the pathogenesis of gastric ulcers, the most common chronic gastrointestinal disease. Common habits such as stress, coffee ingestion, tobacco, alcohol, and nonsteroidal antiinflammatory drugs' consumption contribute to the physiopathology of gastric ulcers. There is an ongoing search to discover novel bioactive gastroprotective and ulcer-healing compounds derived from medicinal plants. Among antiulcer studies using natural products, those focused on isolated compounds have brought promising results, which is important for developing new drugs against gastric ulcers. In this manuscript, we review the published antiulcer studies dedicated to isolated compounds, highlighting the chemical structure and mechanisms of action of each compound and trying to elucidate a structure-activity relationship for the tested compounds.Laboratory of Natural Products Morphology Department Institute of Biosciences São Paulo State University (UNESP)Laboratory of Natural Products Morphology Department Institute of Biosciences São Paulo State University (UNESP)Universidade Estadual Paulista (Unesp)Beserra, Fernando Pereira [UNESP]Rozza, Ariane Leite [UNESP]Vieira, Ana Júlia [UNESP]Sérgio Gushiken, Lucas Fernando [UNESP]Pellizzon, Cláudia Helena [UNESP]2018-12-11T17:28:48Z2018-12-11T17:28:48Z2016-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObject215-234http://dx.doi.org/10.1016/B978-0-444-63603-4.00006-1Studies in Natural Products Chemistry, v. 47, p. 215-234.1572-5995http://hdl.handle.net/11449/17811410.1016/B978-0-444-63603-4.00006-12-s2.0-8497640281200193937798010690000-0002-4494-4180Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengStudies in Natural Products Chemistry0,206info:eu-repo/semantics/openAccess2021-10-27T10:13:54Zoai:repositorio.unesp.br:11449/178114Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:09:46.007275Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Antiulcerogenic Compounds Isolated from Medicinal Plants
title Antiulcerogenic Compounds Isolated from Medicinal Plants
spellingShingle Antiulcerogenic Compounds Isolated from Medicinal Plants
Beserra, Fernando Pereira [UNESP]
alkaloids
gastric ulcer
isolated compounds
phenolic compounds
saponins
terpenes
title_short Antiulcerogenic Compounds Isolated from Medicinal Plants
title_full Antiulcerogenic Compounds Isolated from Medicinal Plants
title_fullStr Antiulcerogenic Compounds Isolated from Medicinal Plants
title_full_unstemmed Antiulcerogenic Compounds Isolated from Medicinal Plants
title_sort Antiulcerogenic Compounds Isolated from Medicinal Plants
author Beserra, Fernando Pereira [UNESP]
author_facet Beserra, Fernando Pereira [UNESP]
Rozza, Ariane Leite [UNESP]
Vieira, Ana Júlia [UNESP]
Sérgio Gushiken, Lucas Fernando [UNESP]
Pellizzon, Cláudia Helena [UNESP]
author_role author
author2 Rozza, Ariane Leite [UNESP]
Vieira, Ana Júlia [UNESP]
Sérgio Gushiken, Lucas Fernando [UNESP]
Pellizzon, Cláudia Helena [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Beserra, Fernando Pereira [UNESP]
Rozza, Ariane Leite [UNESP]
Vieira, Ana Júlia [UNESP]
Sérgio Gushiken, Lucas Fernando [UNESP]
Pellizzon, Cláudia Helena [UNESP]
dc.subject.por.fl_str_mv alkaloids
gastric ulcer
isolated compounds
phenolic compounds
saponins
terpenes
topic alkaloids
gastric ulcer
isolated compounds
phenolic compounds
saponins
terpenes
description The gastric mucosa is continuously exposed to damaging agents that are involved in the pathogenesis of gastric ulcers, the most common chronic gastrointestinal disease. Common habits such as stress, coffee ingestion, tobacco, alcohol, and nonsteroidal antiinflammatory drugs' consumption contribute to the physiopathology of gastric ulcers. There is an ongoing search to discover novel bioactive gastroprotective and ulcer-healing compounds derived from medicinal plants. Among antiulcer studies using natural products, those focused on isolated compounds have brought promising results, which is important for developing new drugs against gastric ulcers. In this manuscript, we review the published antiulcer studies dedicated to isolated compounds, highlighting the chemical structure and mechanisms of action of each compound and trying to elucidate a structure-activity relationship for the tested compounds.
publishDate 2016
dc.date.none.fl_str_mv 2016-01-01
2018-12-11T17:28:48Z
2018-12-11T17:28:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/B978-0-444-63603-4.00006-1
Studies in Natural Products Chemistry, v. 47, p. 215-234.
1572-5995
http://hdl.handle.net/11449/178114
10.1016/B978-0-444-63603-4.00006-1
2-s2.0-84976402812
0019393779801069
0000-0002-4494-4180
url http://dx.doi.org/10.1016/B978-0-444-63603-4.00006-1
http://hdl.handle.net/11449/178114
identifier_str_mv Studies in Natural Products Chemistry, v. 47, p. 215-234.
1572-5995
10.1016/B978-0-444-63603-4.00006-1
2-s2.0-84976402812
0019393779801069
0000-0002-4494-4180
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Studies in Natural Products Chemistry
0,206
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 215-234
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129167340863488

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