Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.vas.2020.100148 http://hdl.handle.net/11449/208336 |
Resumo: | Ten male sheep (Sheep group; SGk) and seven male goats (Goat group; GGks+) were used in this study. The objective was to compare the use of racemic ketamine or ketamine S(+) associated with lidocaine on spinal anesthesia and evaluate if the drugs leads to a surgical anesthesia state, as well as to verify the cardiorespiratory, sedative and motor effects of this technique in these species. After correct placement of the needle in the subarachnoid space, 3.0 mg kg−1 of racemic ketamine (SGk) or ketamine S(+) (GGks+), both diluted in 1.5 mg kg−1 of 2% lidocaine, were administered. Evaluations were performed during orchiectomy, at times 0 (T0), 5 (T5), 10 (T10), 20 (T20), 30 (T30) and 60 (T60) minutes after subarachnoid anesthesia administration. No significant changes in heart and respiratory rates were observed in both experimental groups. All animals showed surgical analgesia and stood conscious or slightly sedated with ataxia immediately after the drugs administration (T5), allowing the execution of bilateral orchiectomy. The ataxia in SGk was classified as severe with recumbency in 80% of the animals, moderate ataxia in 10% of the animals, and mild ataxia in 10% of the animals. All goats (GGks+; 100%) presented severe ataxia and recumbency. At 60 min, animals of both groups were in standing position and with normal gait. Subarachnoid RS-ketamine and ketamine S(+) (3 mg kg−1), associated with lidocaine in sheep and goats, produces surgical anesthesia and recumbency without causing cardiorespiratory abnormalities, regurgitation and bloating. |
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Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesiaAnalgesiaAnesthesiaRuminantsSedativeTen male sheep (Sheep group; SGk) and seven male goats (Goat group; GGks+) were used in this study. The objective was to compare the use of racemic ketamine or ketamine S(+) associated with lidocaine on spinal anesthesia and evaluate if the drugs leads to a surgical anesthesia state, as well as to verify the cardiorespiratory, sedative and motor effects of this technique in these species. After correct placement of the needle in the subarachnoid space, 3.0 mg kg−1 of racemic ketamine (SGk) or ketamine S(+) (GGks+), both diluted in 1.5 mg kg−1 of 2% lidocaine, were administered. Evaluations were performed during orchiectomy, at times 0 (T0), 5 (T5), 10 (T10), 20 (T20), 30 (T30) and 60 (T60) minutes after subarachnoid anesthesia administration. No significant changes in heart and respiratory rates were observed in both experimental groups. All animals showed surgical analgesia and stood conscious or slightly sedated with ataxia immediately after the drugs administration (T5), allowing the execution of bilateral orchiectomy. The ataxia in SGk was classified as severe with recumbency in 80% of the animals, moderate ataxia in 10% of the animals, and mild ataxia in 10% of the animals. All goats (GGks+; 100%) presented severe ataxia and recumbency. At 60 min, animals of both groups were in standing position and with normal gait. Subarachnoid RS-ketamine and ketamine S(+) (3 mg kg−1), associated with lidocaine in sheep and goats, produces surgical anesthesia and recumbency without causing cardiorespiratory abnormalities, regurgitation and bloating.Department of Veterinary Medicine University of São Paulo (USP) Faculty of Animal Science and Food EngineeringFMU UniversityNorte Fluminense State University Campos dos GoytacazesDepartment of Veterinary Sciences Texas Tech University (TTU) College of Agricultural Sciences and Natural ResourcesDepartament of Veterinary Medicine Santa Catarina State UniversityDepartment of Veterinary Internal Medicine and Surgery São Paulo State University (UNESP) School of Agricultural and Veterinarian SciencesDepartment of Veterinary Internal Medicine and Surgery São Paulo State University (UNESP) School of Agricultural and Veterinarian SciencesUniversidade de São Paulo (USP)FMU UniversityCampos dos GoytacazesCollege of Agricultural Sciences and Natural ResourcesSanta Catarina State UniversityUniversidade Estadual Paulista (Unesp)Dória, Renata Gebara SampaioFerraz, Gesiane Ribeiro LeãoFilippo, Paula Alessandra DiLacerenza, Milena DominguesFernandes, Letícia MartinsOleskovicz, NilsonValadão, Carlos Augusto Araújo [UNESP]2021-06-25T11:10:32Z2021-06-25T11:10:32Z2021-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.vas.2020.100148Veterinary and Animal Science, v. 11.2451-943Xhttp://hdl.handle.net/11449/20833610.1016/j.vas.2020.1001482-s2.0-85099691548Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVeterinary and Animal Scienceinfo:eu-repo/semantics/openAccess2024-06-06T14:10:21Zoai:repositorio.unesp.br:11449/208336Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:36:11.595393Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia |
title |
Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia |
spellingShingle |
Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia Dória, Renata Gebara Sampaio Analgesia Anesthesia Ruminants Sedative |
title_short |
Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia |
title_full |
Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia |
title_fullStr |
Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia |
title_full_unstemmed |
Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia |
title_sort |
Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia |
author |
Dória, Renata Gebara Sampaio |
author_facet |
Dória, Renata Gebara Sampaio Ferraz, Gesiane Ribeiro Leão Filippo, Paula Alessandra Di Lacerenza, Milena Domingues Fernandes, Letícia Martins Oleskovicz, Nilson Valadão, Carlos Augusto Araújo [UNESP] |
author_role |
author |
author2 |
Ferraz, Gesiane Ribeiro Leão Filippo, Paula Alessandra Di Lacerenza, Milena Domingues Fernandes, Letícia Martins Oleskovicz, Nilson Valadão, Carlos Augusto Araújo [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) FMU University Campos dos Goytacazes College of Agricultural Sciences and Natural Resources Santa Catarina State University Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Dória, Renata Gebara Sampaio Ferraz, Gesiane Ribeiro Leão Filippo, Paula Alessandra Di Lacerenza, Milena Domingues Fernandes, Letícia Martins Oleskovicz, Nilson Valadão, Carlos Augusto Araújo [UNESP] |
dc.subject.por.fl_str_mv |
Analgesia Anesthesia Ruminants Sedative |
topic |
Analgesia Anesthesia Ruminants Sedative |
description |
Ten male sheep (Sheep group; SGk) and seven male goats (Goat group; GGks+) were used in this study. The objective was to compare the use of racemic ketamine or ketamine S(+) associated with lidocaine on spinal anesthesia and evaluate if the drugs leads to a surgical anesthesia state, as well as to verify the cardiorespiratory, sedative and motor effects of this technique in these species. After correct placement of the needle in the subarachnoid space, 3.0 mg kg−1 of racemic ketamine (SGk) or ketamine S(+) (GGks+), both diluted in 1.5 mg kg−1 of 2% lidocaine, were administered. Evaluations were performed during orchiectomy, at times 0 (T0), 5 (T5), 10 (T10), 20 (T20), 30 (T30) and 60 (T60) minutes after subarachnoid anesthesia administration. No significant changes in heart and respiratory rates were observed in both experimental groups. All animals showed surgical analgesia and stood conscious or slightly sedated with ataxia immediately after the drugs administration (T5), allowing the execution of bilateral orchiectomy. The ataxia in SGk was classified as severe with recumbency in 80% of the animals, moderate ataxia in 10% of the animals, and mild ataxia in 10% of the animals. All goats (GGks+; 100%) presented severe ataxia and recumbency. At 60 min, animals of both groups were in standing position and with normal gait. Subarachnoid RS-ketamine and ketamine S(+) (3 mg kg−1), associated with lidocaine in sheep and goats, produces surgical anesthesia and recumbency without causing cardiorespiratory abnormalities, regurgitation and bloating. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T11:10:32Z 2021-06-25T11:10:32Z 2021-03-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.vas.2020.100148 Veterinary and Animal Science, v. 11. 2451-943X http://hdl.handle.net/11449/208336 10.1016/j.vas.2020.100148 2-s2.0-85099691548 |
url |
http://dx.doi.org/10.1016/j.vas.2020.100148 http://hdl.handle.net/11449/208336 |
identifier_str_mv |
Veterinary and Animal Science, v. 11. 2451-943X 10.1016/j.vas.2020.100148 2-s2.0-85099691548 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Veterinary and Animal Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129095203028992 |