Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia

Detalhes bibliográficos
Autor(a) principal: Dória, Renata Gebara Sampaio
Data de Publicação: 2021
Outros Autores: Ferraz, Gesiane Ribeiro Leão, Filippo, Paula Alessandra Di, Lacerenza, Milena Domingues, Fernandes, Letícia Martins, Oleskovicz, Nilson, Valadão, Carlos Augusto Araújo [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.vas.2020.100148
http://hdl.handle.net/11449/208336
Resumo: Ten male sheep (Sheep group; SGk) and seven male goats (Goat group; GGks+) were used in this study. The objective was to compare the use of racemic ketamine or ketamine S(+) associated with lidocaine on spinal anesthesia and evaluate if the drugs leads to a surgical anesthesia state, as well as to verify the cardiorespiratory, sedative and motor effects of this technique in these species. After correct placement of the needle in the subarachnoid space, 3.0 mg kg−1 of racemic ketamine (SGk) or ketamine S(+) (GGks+), both diluted in 1.5 mg kg−1 of 2% lidocaine, were administered. Evaluations were performed during orchiectomy, at times 0 (T0), 5 (T5), 10 (T10), 20 (T20), 30 (T30) and 60 (T60) minutes after subarachnoid anesthesia administration. No significant changes in heart and respiratory rates were observed in both experimental groups. All animals showed surgical analgesia and stood conscious or slightly sedated with ataxia immediately after the drugs administration (T5), allowing the execution of bilateral orchiectomy. The ataxia in SGk was classified as severe with recumbency in 80% of the animals, moderate ataxia in 10% of the animals, and mild ataxia in 10% of the animals. All goats (GGks+; 100%) presented severe ataxia and recumbency. At 60 min, animals of both groups were in standing position and with normal gait. Subarachnoid RS-ketamine and ketamine S(+) (3 mg kg−1), associated with lidocaine in sheep and goats, produces surgical anesthesia and recumbency without causing cardiorespiratory abnormalities, regurgitation and bloating.
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spelling Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesiaAnalgesiaAnesthesiaRuminantsSedativeTen male sheep (Sheep group; SGk) and seven male goats (Goat group; GGks+) were used in this study. The objective was to compare the use of racemic ketamine or ketamine S(+) associated with lidocaine on spinal anesthesia and evaluate if the drugs leads to a surgical anesthesia state, as well as to verify the cardiorespiratory, sedative and motor effects of this technique in these species. After correct placement of the needle in the subarachnoid space, 3.0 mg kg−1 of racemic ketamine (SGk) or ketamine S(+) (GGks+), both diluted in 1.5 mg kg−1 of 2% lidocaine, were administered. Evaluations were performed during orchiectomy, at times 0 (T0), 5 (T5), 10 (T10), 20 (T20), 30 (T30) and 60 (T60) minutes after subarachnoid anesthesia administration. No significant changes in heart and respiratory rates were observed in both experimental groups. All animals showed surgical analgesia and stood conscious or slightly sedated with ataxia immediately after the drugs administration (T5), allowing the execution of bilateral orchiectomy. The ataxia in SGk was classified as severe with recumbency in 80% of the animals, moderate ataxia in 10% of the animals, and mild ataxia in 10% of the animals. All goats (GGks+; 100%) presented severe ataxia and recumbency. At 60 min, animals of both groups were in standing position and with normal gait. Subarachnoid RS-ketamine and ketamine S(+) (3 mg kg−1), associated with lidocaine in sheep and goats, produces surgical anesthesia and recumbency without causing cardiorespiratory abnormalities, regurgitation and bloating.Department of Veterinary Medicine University of São Paulo (USP) Faculty of Animal Science and Food EngineeringFMU UniversityNorte Fluminense State University Campos dos GoytacazesDepartment of Veterinary Sciences Texas Tech University (TTU) College of Agricultural Sciences and Natural ResourcesDepartament of Veterinary Medicine Santa Catarina State UniversityDepartment of Veterinary Internal Medicine and Surgery São Paulo State University (UNESP) School of Agricultural and Veterinarian SciencesDepartment of Veterinary Internal Medicine and Surgery São Paulo State University (UNESP) School of Agricultural and Veterinarian SciencesUniversidade de São Paulo (USP)FMU UniversityCampos dos GoytacazesCollege of Agricultural Sciences and Natural ResourcesSanta Catarina State UniversityUniversidade Estadual Paulista (Unesp)Dória, Renata Gebara SampaioFerraz, Gesiane Ribeiro LeãoFilippo, Paula Alessandra DiLacerenza, Milena DominguesFernandes, Letícia MartinsOleskovicz, NilsonValadão, Carlos Augusto Araújo [UNESP]2021-06-25T11:10:32Z2021-06-25T11:10:32Z2021-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.vas.2020.100148Veterinary and Animal Science, v. 11.2451-943Xhttp://hdl.handle.net/11449/20833610.1016/j.vas.2020.1001482-s2.0-85099691548Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVeterinary and Animal Scienceinfo:eu-repo/semantics/openAccess2024-06-06T14:10:21Zoai:repositorio.unesp.br:11449/208336Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:36:11.595393Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia
title Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia
spellingShingle Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia
Dória, Renata Gebara Sampaio
Analgesia
Anesthesia
Ruminants
Sedative
title_short Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia
title_full Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia
title_fullStr Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia
title_full_unstemmed Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia
title_sort Subarachnoid ketamine and ketamine s (+) associated with lidocaine in sheep and goats anesthesia
author Dória, Renata Gebara Sampaio
author_facet Dória, Renata Gebara Sampaio
Ferraz, Gesiane Ribeiro Leão
Filippo, Paula Alessandra Di
Lacerenza, Milena Domingues
Fernandes, Letícia Martins
Oleskovicz, Nilson
Valadão, Carlos Augusto Araújo [UNESP]
author_role author
author2 Ferraz, Gesiane Ribeiro Leão
Filippo, Paula Alessandra Di
Lacerenza, Milena Domingues
Fernandes, Letícia Martins
Oleskovicz, Nilson
Valadão, Carlos Augusto Araújo [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
FMU University
Campos dos Goytacazes
College of Agricultural Sciences and Natural Resources
Santa Catarina State University
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Dória, Renata Gebara Sampaio
Ferraz, Gesiane Ribeiro Leão
Filippo, Paula Alessandra Di
Lacerenza, Milena Domingues
Fernandes, Letícia Martins
Oleskovicz, Nilson
Valadão, Carlos Augusto Araújo [UNESP]
dc.subject.por.fl_str_mv Analgesia
Anesthesia
Ruminants
Sedative
topic Analgesia
Anesthesia
Ruminants
Sedative
description Ten male sheep (Sheep group; SGk) and seven male goats (Goat group; GGks+) were used in this study. The objective was to compare the use of racemic ketamine or ketamine S(+) associated with lidocaine on spinal anesthesia and evaluate if the drugs leads to a surgical anesthesia state, as well as to verify the cardiorespiratory, sedative and motor effects of this technique in these species. After correct placement of the needle in the subarachnoid space, 3.0 mg kg−1 of racemic ketamine (SGk) or ketamine S(+) (GGks+), both diluted in 1.5 mg kg−1 of 2% lidocaine, were administered. Evaluations were performed during orchiectomy, at times 0 (T0), 5 (T5), 10 (T10), 20 (T20), 30 (T30) and 60 (T60) minutes after subarachnoid anesthesia administration. No significant changes in heart and respiratory rates were observed in both experimental groups. All animals showed surgical analgesia and stood conscious or slightly sedated with ataxia immediately after the drugs administration (T5), allowing the execution of bilateral orchiectomy. The ataxia in SGk was classified as severe with recumbency in 80% of the animals, moderate ataxia in 10% of the animals, and mild ataxia in 10% of the animals. All goats (GGks+; 100%) presented severe ataxia and recumbency. At 60 min, animals of both groups were in standing position and with normal gait. Subarachnoid RS-ketamine and ketamine S(+) (3 mg kg−1), associated with lidocaine in sheep and goats, produces surgical anesthesia and recumbency without causing cardiorespiratory abnormalities, regurgitation and bloating.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-25T11:10:32Z
2021-06-25T11:10:32Z
2021-03-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.vas.2020.100148
Veterinary and Animal Science, v. 11.
2451-943X
http://hdl.handle.net/11449/208336
10.1016/j.vas.2020.100148
2-s2.0-85099691548
url http://dx.doi.org/10.1016/j.vas.2020.100148
http://hdl.handle.net/11449/208336
identifier_str_mv Veterinary and Animal Science, v. 11.
2451-943X
10.1016/j.vas.2020.100148
2-s2.0-85099691548
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Veterinary and Animal Science
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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