Porosity of temporary denture soft liners containing antifungal agents
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/123014 |
Resumo: | Incorporation of antifungals in temporary denture soft liners has been recommended for denture stomatitis treatment; however, it may affect their properties. Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner (Trusoft) modified by minimum inhibitory concentrations (MICs) of antifungal agents for Candida albicans biofilm. Material and Methods: The porosity was measured by water absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65×10×3.3 mm) of both materials was 50% anhydrous calcium chloride (S50). Then, the porosity factor (PF) was calculated for the study groups (n=10) formed by specimens without (control) or with drug incorporation at MICs (nystatin: Ny-0.032 g, chlorhexidine diacetate: Chx-0.064 g, or ketoconazole: Ke-0.128 g each per gram of soft liner powder) after storage in distilled water or S50 for 24 h, seven and 14 d. Data were statistically analyzed by 4-way repeated measures ANOVA and Tukey's test (α=.05). Results: Ke resulted in no significant changes in PF for both liners in water over 14 days (p>;0.05). Compared with the controls, Softone and Trusoft PFs were increased at 14-day water immersion only after addition of Ny and Chx, and Chx, respectively (p;0.05). In all experimental conditions, Softone and Trusoft PFs were significantly lower when immersed in S50 compared with distilled water (p |
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oai:revistas.usp.br:article/123014 |
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USP-17 |
network_name_str |
Journal of applied oral science (Online) |
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Porosity of temporary denture soft liners containing antifungal agents Incorporation of antifungals in temporary denture soft liners has been recommended for denture stomatitis treatment; however, it may affect their properties. Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner (Trusoft) modified by minimum inhibitory concentrations (MICs) of antifungal agents for Candida albicans biofilm. Material and Methods: The porosity was measured by water absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65×10×3.3 mm) of both materials was 50% anhydrous calcium chloride (S50). Then, the porosity factor (PF) was calculated for the study groups (n=10) formed by specimens without (control) or with drug incorporation at MICs (nystatin: Ny-0.032 g, chlorhexidine diacetate: Chx-0.064 g, or ketoconazole: Ke-0.128 g each per gram of soft liner powder) after storage in distilled water or S50 for 24 h, seven and 14 d. Data were statistically analyzed by 4-way repeated measures ANOVA and Tukey's test (α=.05). Results: Ke resulted in no significant changes in PF for both liners in water over 14 days (p>;0.05). Compared with the controls, Softone and Trusoft PFs were increased at 14-day water immersion only after addition of Ny and Chx, and Chx, respectively (p;0.05). In all experimental conditions, Softone and Trusoft PFs were significantly lower when immersed in S50 compared with distilled water (pUniversidade de São Paulo. Faculdade de Odontologia de Bauru2016-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/12301410.1590/1678-775720160092Journal of Applied Oral Science; Vol. 24 No. 5 (2016); 453-461Journal of Applied Oral Science; Vol. 24 Núm. 5 (2016); 453-461Journal of Applied Oral Science; v. 24 n. 5 (2016); 453-4611678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/123014/119395Copyright (c) 2016 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessLima, Jozely Francisca MelloMaciel, Janaína GomesHotta, JulianaVizoto, Ana Carolina PeroHonório, Heitor MarquesUrban, Vanessa MiglioriniNeppelenbroek, Karin Hermana2016-11-18T10:37:37Zoai:revistas.usp.br:article/123014Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2016-11-18T10:37:37Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Porosity of temporary denture soft liners containing antifungal agents |
title |
Porosity of temporary denture soft liners containing antifungal agents |
spellingShingle |
Porosity of temporary denture soft liners containing antifungal agents Lima, Jozely Francisca Mello |
title_short |
Porosity of temporary denture soft liners containing antifungal agents |
title_full |
Porosity of temporary denture soft liners containing antifungal agents |
title_fullStr |
Porosity of temporary denture soft liners containing antifungal agents |
title_full_unstemmed |
Porosity of temporary denture soft liners containing antifungal agents |
title_sort |
Porosity of temporary denture soft liners containing antifungal agents |
author |
Lima, Jozely Francisca Mello |
author_facet |
Lima, Jozely Francisca Mello Maciel, Janaína Gomes Hotta, Juliana Vizoto, Ana Carolina Pero Honório, Heitor Marques Urban, Vanessa Migliorini Neppelenbroek, Karin Hermana |
author_role |
author |
author2 |
Maciel, Janaína Gomes Hotta, Juliana Vizoto, Ana Carolina Pero Honório, Heitor Marques Urban, Vanessa Migliorini Neppelenbroek, Karin Hermana |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Lima, Jozely Francisca Mello Maciel, Janaína Gomes Hotta, Juliana Vizoto, Ana Carolina Pero Honório, Heitor Marques Urban, Vanessa Migliorini Neppelenbroek, Karin Hermana |
description |
Incorporation of antifungals in temporary denture soft liners has been recommended for denture stomatitis treatment; however, it may affect their properties. Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner (Trusoft) modified by minimum inhibitory concentrations (MICs) of antifungal agents for Candida albicans biofilm. Material and Methods: The porosity was measured by water absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65×10×3.3 mm) of both materials was 50% anhydrous calcium chloride (S50). Then, the porosity factor (PF) was calculated for the study groups (n=10) formed by specimens without (control) or with drug incorporation at MICs (nystatin: Ny-0.032 g, chlorhexidine diacetate: Chx-0.064 g, or ketoconazole: Ke-0.128 g each per gram of soft liner powder) after storage in distilled water or S50 for 24 h, seven and 14 d. Data were statistically analyzed by 4-way repeated measures ANOVA and Tukey's test (α=.05). Results: Ke resulted in no significant changes in PF for both liners in water over 14 days (p>;0.05). Compared with the controls, Softone and Trusoft PFs were increased at 14-day water immersion only after addition of Ny and Chx, and Chx, respectively (p;0.05). In all experimental conditions, Softone and Trusoft PFs were significantly lower when immersed in S50 compared with distilled water (p |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/123014 10.1590/1678-775720160092 |
url |
https://www.revistas.usp.br/jaos/article/view/123014 |
identifier_str_mv |
10.1590/1678-775720160092 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/123014/119395 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2016 Journal of Applied Oral Science info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2016 Journal of Applied Oral Science |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 24 No. 5 (2016); 453-461 Journal of Applied Oral Science; Vol. 24 Núm. 5 (2016); 453-461 Journal of Applied Oral Science; v. 24 n. 5 (2016); 453-461 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221679684681728 |