Porosity of temporary denture soft liners containing antifungal agents

Detalhes bibliográficos
Autor(a) principal: Lima, Jozely Francisca Mello
Data de Publicação: 2016
Outros Autores: Maciel, Janaína Gomes, Hotta, Juliana, Vizoto, Ana Carolina Pero, Honório, Heitor Marques, Urban, Vanessa Migliorini, Neppelenbroek, Karin Hermana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/123014
Resumo: Incorporation of antifungals in temporary denture soft liners has been recommended for denture stomatitis treatment; however, it may affect their properties. Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner (Trusoft) modified by minimum inhibitory concentrations (MICs) of antifungal agents for Candida albicans biofilm. Material and Methods: The porosity was measured by water absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65×10×3.3 mm) of both materials was 50% anhydrous calcium chloride (S50). Then, the porosity factor (PF) was calculated for the study groups (n=10) formed by specimens without (control) or with drug incorporation at MICs (nystatin: Ny-0.032 g, chlorhexidine diacetate: Chx-0.064 g, or ketoconazole: Ke-0.128 g each per gram of soft liner powder) after storage in distilled water or S50 for 24 h, seven and 14 d. Data were statistically analyzed by 4-way repeated measures ANOVA and Tukey's test (α=.05). Results: Ke resulted in no significant changes in PF for both liners in water over 14 days (p>;0.05). Compared with the controls, Softone and Trusoft PFs were increased at 14-day water immersion only after addition of Ny and Chx, and Chx, respectively (p;0.05). In all experimental conditions, Softone and Trusoft PFs were significantly lower when immersed in S50 compared with distilled water (p
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spelling Porosity of temporary denture soft liners containing antifungal agents Incorporation of antifungals in temporary denture soft liners has been recommended for denture stomatitis treatment; however, it may affect their properties. Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner (Trusoft) modified by minimum inhibitory concentrations (MICs) of antifungal agents for Candida albicans biofilm. Material and Methods: The porosity was measured by water absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65×10×3.3 mm) of both materials was 50% anhydrous calcium chloride (S50). Then, the porosity factor (PF) was calculated for the study groups (n=10) formed by specimens without (control) or with drug incorporation at MICs (nystatin: Ny-0.032 g, chlorhexidine diacetate: Chx-0.064 g, or ketoconazole: Ke-0.128 g each per gram of soft liner powder) after storage in distilled water or S50 for 24 h, seven and 14 d. Data were statistically analyzed by 4-way repeated measures ANOVA and Tukey's test (α=.05). Results: Ke resulted in no significant changes in PF for both liners in water over 14 days (p>;0.05). Compared with the controls, Softone and Trusoft PFs were increased at 14-day water immersion only after addition of Ny and Chx, and Chx, respectively (p;0.05). In all experimental conditions, Softone and Trusoft PFs were significantly lower when immersed in S50 compared with distilled water (pUniversidade de São Paulo. Faculdade de Odontologia de Bauru2016-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/12301410.1590/1678-775720160092Journal of Applied Oral Science; Vol. 24 No. 5 (2016); 453-461Journal of Applied Oral Science; Vol. 24 Núm. 5 (2016); 453-461Journal of Applied Oral Science; v. 24 n. 5 (2016); 453-4611678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/123014/119395Copyright (c) 2016 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessLima, Jozely Francisca MelloMaciel, Janaína GomesHotta, JulianaVizoto, Ana Carolina PeroHonório, Heitor MarquesUrban, Vanessa MiglioriniNeppelenbroek, Karin Hermana2016-11-18T10:37:37Zoai:revistas.usp.br:article/123014Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2016-11-18T10:37:37Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Porosity of temporary denture soft liners containing antifungal agents
title Porosity of temporary denture soft liners containing antifungal agents
spellingShingle Porosity of temporary denture soft liners containing antifungal agents
Lima, Jozely Francisca Mello
title_short Porosity of temporary denture soft liners containing antifungal agents
title_full Porosity of temporary denture soft liners containing antifungal agents
title_fullStr Porosity of temporary denture soft liners containing antifungal agents
title_full_unstemmed Porosity of temporary denture soft liners containing antifungal agents
title_sort Porosity of temporary denture soft liners containing antifungal agents
author Lima, Jozely Francisca Mello
author_facet Lima, Jozely Francisca Mello
Maciel, Janaína Gomes
Hotta, Juliana
Vizoto, Ana Carolina Pero
Honório, Heitor Marques
Urban, Vanessa Migliorini
Neppelenbroek, Karin Hermana
author_role author
author2 Maciel, Janaína Gomes
Hotta, Juliana
Vizoto, Ana Carolina Pero
Honório, Heitor Marques
Urban, Vanessa Migliorini
Neppelenbroek, Karin Hermana
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lima, Jozely Francisca Mello
Maciel, Janaína Gomes
Hotta, Juliana
Vizoto, Ana Carolina Pero
Honório, Heitor Marques
Urban, Vanessa Migliorini
Neppelenbroek, Karin Hermana
description Incorporation of antifungals in temporary denture soft liners has been recommended for denture stomatitis treatment; however, it may affect their properties. Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner (Trusoft) modified by minimum inhibitory concentrations (MICs) of antifungal agents for Candida albicans biofilm. Material and Methods: The porosity was measured by water absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65×10×3.3 mm) of both materials was 50% anhydrous calcium chloride (S50). Then, the porosity factor (PF) was calculated for the study groups (n=10) formed by specimens without (control) or with drug incorporation at MICs (nystatin: Ny-0.032 g, chlorhexidine diacetate: Chx-0.064 g, or ketoconazole: Ke-0.128 g each per gram of soft liner powder) after storage in distilled water or S50 for 24 h, seven and 14 d. Data were statistically analyzed by 4-way repeated measures ANOVA and Tukey's test (α=.05). Results: Ke resulted in no significant changes in PF for both liners in water over 14 days (p>;0.05). Compared with the controls, Softone and Trusoft PFs were increased at 14-day water immersion only after addition of Ny and Chx, and Chx, respectively (p;0.05). In all experimental conditions, Softone and Trusoft PFs were significantly lower when immersed in S50 compared with distilled water (p
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/123014
10.1590/1678-775720160092
url https://www.revistas.usp.br/jaos/article/view/123014
identifier_str_mv 10.1590/1678-775720160092
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/123014/119395
dc.rights.driver.fl_str_mv Copyright (c) 2016 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2016 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 24 No. 5 (2016); 453-461
Journal of Applied Oral Science; Vol. 24 Núm. 5 (2016); 453-461
Journal of Applied Oral Science; v. 24 n. 5 (2016); 453-461
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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