In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment

Detalhes bibliográficos
Autor(a) principal: Duque, Cristiane
Data de Publicação: 2017
Outros Autores: Aida, Kelly Limi, Pereira, Jesse Augusto, Teixeira, Gláucia Schuindt, Caldo-Teixeira, Angela Scarparo, Perrone, Luciana Rodrigues, Caiaffa, Karina Sampaio, Negrini, Thais de Cássia, Castilho, Aline Rogéria Freire de, Costa, Carlos Alberto de Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/140023
Resumo: Objectives: Addition of chlorhexidine has enhanced the antimicrobial effect of glass ionomer cement (GIC) indicated to Atraumatic Restorative Treatment (ART); however, the impact of this mixture on the properties of these materials and on the longevity of restorations must be investigated. The aim of this study was to evaluate the effects of incorporating chlorhexidine (CHX) in the in vitro biological and chemical-mechanical properties of GIC and in vivo clinical/ microbiological follow-up of the ART with GIC containing or not CHX. Material and Methods: For in vitro studies, groups were divided into GIC, GIC with 1.25% CHX, and GIC with 2.5% CHX. Antimicrobial activity of GIC was analyzed using agar diffusion and anti-biofilm assays. Cytotoxic effects, compressive tensile strength, microhardness and fluoride (F) release were also evaluated. A randomized controlled trial was conducted on 36 children that received ART either with GIC or GIC with CHX. Saliva and biofilm were collected for mutans streptococci (MS) counts and the survival rate of restorations was checked after 7 days, 3 months and one year after ART. ANOVA/Tukey or Kruskal-Wallis/ Mann-Whitney tests were performed for in vitro tests and in vivo microbiological analysis. The Kaplan-Meier method and Log rank tests were applied to estimate survival percentages of restorations (p
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spelling In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative TreatmentDental atraumatic restorative treatmentChlorhexidineGlass ionomer cements Objectives: Addition of chlorhexidine has enhanced the antimicrobial effect of glass ionomer cement (GIC) indicated to Atraumatic Restorative Treatment (ART); however, the impact of this mixture on the properties of these materials and on the longevity of restorations must be investigated. The aim of this study was to evaluate the effects of incorporating chlorhexidine (CHX) in the in vitro biological and chemical-mechanical properties of GIC and in vivo clinical/ microbiological follow-up of the ART with GIC containing or not CHX. Material and Methods: For in vitro studies, groups were divided into GIC, GIC with 1.25% CHX, and GIC with 2.5% CHX. Antimicrobial activity of GIC was analyzed using agar diffusion and anti-biofilm assays. Cytotoxic effects, compressive tensile strength, microhardness and fluoride (F) release were also evaluated. A randomized controlled trial was conducted on 36 children that received ART either with GIC or GIC with CHX. Saliva and biofilm were collected for mutans streptococci (MS) counts and the survival rate of restorations was checked after 7 days, 3 months and one year after ART. ANOVA/Tukey or Kruskal-Wallis/ Mann-Whitney tests were performed for in vitro tests and in vivo microbiological analysis. The Kaplan-Meier method and Log rank tests were applied to estimate survival percentages of restorations (pUniversidade de São Paulo. Faculdade de Odontologia de Bauru2017-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/14002310.1590/1678-7757-2016-0195Journal of Applied Oral Science; Vol. 25 No. 5 (2017); 541-550Journal of Applied Oral Science; Vol. 25 Núm. 5 (2017); 541-550Journal of Applied Oral Science; v. 25 n. 5 (2017); 541-5501678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/140023/135223Copyright (c) 2017 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessDuque, CristianeAida, Kelly LimiPereira, Jesse AugustoTeixeira, Gláucia SchuindtCaldo-Teixeira, Angela ScarparoPerrone, Luciana RodriguesCaiaffa, Karina SampaioNegrini, Thais de CássiaCastilho, Aline Rogéria Freire deCosta, Carlos Alberto de Souza2017-10-25T11:51:34Zoai:revistas.usp.br:article/140023Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2017-10-25T11:51:34Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment
title In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment
spellingShingle In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment
Duque, Cristiane
Dental atraumatic restorative treatment
Chlorhexidine
Glass ionomer cements
title_short In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment
title_full In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment
title_fullStr In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment
title_full_unstemmed In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment
title_sort In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment
author Duque, Cristiane
author_facet Duque, Cristiane
Aida, Kelly Limi
Pereira, Jesse Augusto
Teixeira, Gláucia Schuindt
Caldo-Teixeira, Angela Scarparo
Perrone, Luciana Rodrigues
Caiaffa, Karina Sampaio
Negrini, Thais de Cássia
Castilho, Aline Rogéria Freire de
Costa, Carlos Alberto de Souza
author_role author
author2 Aida, Kelly Limi
Pereira, Jesse Augusto
Teixeira, Gláucia Schuindt
Caldo-Teixeira, Angela Scarparo
Perrone, Luciana Rodrigues
Caiaffa, Karina Sampaio
Negrini, Thais de Cássia
Castilho, Aline Rogéria Freire de
Costa, Carlos Alberto de Souza
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Duque, Cristiane
Aida, Kelly Limi
Pereira, Jesse Augusto
Teixeira, Gláucia Schuindt
Caldo-Teixeira, Angela Scarparo
Perrone, Luciana Rodrigues
Caiaffa, Karina Sampaio
Negrini, Thais de Cássia
Castilho, Aline Rogéria Freire de
Costa, Carlos Alberto de Souza
dc.subject.por.fl_str_mv Dental atraumatic restorative treatment
Chlorhexidine
Glass ionomer cements
topic Dental atraumatic restorative treatment
Chlorhexidine
Glass ionomer cements
description Objectives: Addition of chlorhexidine has enhanced the antimicrobial effect of glass ionomer cement (GIC) indicated to Atraumatic Restorative Treatment (ART); however, the impact of this mixture on the properties of these materials and on the longevity of restorations must be investigated. The aim of this study was to evaluate the effects of incorporating chlorhexidine (CHX) in the in vitro biological and chemical-mechanical properties of GIC and in vivo clinical/ microbiological follow-up of the ART with GIC containing or not CHX. Material and Methods: For in vitro studies, groups were divided into GIC, GIC with 1.25% CHX, and GIC with 2.5% CHX. Antimicrobial activity of GIC was analyzed using agar diffusion and anti-biofilm assays. Cytotoxic effects, compressive tensile strength, microhardness and fluoride (F) release were also evaluated. A randomized controlled trial was conducted on 36 children that received ART either with GIC or GIC with CHX. Saliva and biofilm were collected for mutans streptococci (MS) counts and the survival rate of restorations was checked after 7 days, 3 months and one year after ART. ANOVA/Tukey or Kruskal-Wallis/ Mann-Whitney tests were performed for in vitro tests and in vivo microbiological analysis. The Kaplan-Meier method and Log rank tests were applied to estimate survival percentages of restorations (p
publishDate 2017
dc.date.none.fl_str_mv 2017-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/140023
10.1590/1678-7757-2016-0195
url https://www.revistas.usp.br/jaos/article/view/140023
identifier_str_mv 10.1590/1678-7757-2016-0195
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/140023/135223
dc.rights.driver.fl_str_mv Copyright (c) 2017 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 25 No. 5 (2017); 541-550
Journal of Applied Oral Science; Vol. 25 Núm. 5 (2017); 541-550
Journal of Applied Oral Science; v. 25 n. 5 (2017); 541-550
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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