Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/19661 |
Resumo: | OBJECTIVE: Serial C-reactive protein measurements have been used to diagnose and monitor the response to therapy in patients with pneumonia and other infectious diseases. Nonetheless, the role of C-reactive protein measurement after surgical treatment for pleural empyema is not well defined. The aim of this study is to describe the behavior of C-reactive protein levels after the surgical treatment of pleural empyema and to correlate this parameter with the patient's prognosis. METHODS: We retrospectively analyzed the records of patients with pleural empyema treated by either chest-tube drainage or surgery from January 2006 to December 2008. C-reactive protein levels were recorded preoperatively and 2 and 7 days postoperatively. The clinical outcome was binary: success or failure (mortality or the need for repeated pleural intervention). RESULTS: The study group comprised fifty-two patients. The median C-reactive protein values were as follows: 146 mg/L (pre-operative), 134 mg/L (post-operative day 2), and 116 mg/L (post-operative day 7). There was a trend toward a decrease in these values during the first week after surgery, but this difference was only statistically significant on day 7 after surgery. Over the first week after surgery, the C-reactive protein values decreased similarly in both groups (successful and failed treatment). No correlation between the preoperative C-reactive protein level and the clinical outcome was found. CONCLUSIONS: We observed that, in contrast to other medical conditions, C-reactive protein levels fall slowly during the first postoperative week in patients who have undergone surgical treatment for pleural empyema. No correlation between the perioperative C-reactive protein level and the clinical outcome was observed. |
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Clinics |
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Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyemaPleural EmpyemaC-Reactive ProteinTreatment OutcomeSurgeryOBJECTIVE: Serial C-reactive protein measurements have been used to diagnose and monitor the response to therapy in patients with pneumonia and other infectious diseases. Nonetheless, the role of C-reactive protein measurement after surgical treatment for pleural empyema is not well defined. The aim of this study is to describe the behavior of C-reactive protein levels after the surgical treatment of pleural empyema and to correlate this parameter with the patient's prognosis. METHODS: We retrospectively analyzed the records of patients with pleural empyema treated by either chest-tube drainage or surgery from January 2006 to December 2008. C-reactive protein levels were recorded preoperatively and 2 and 7 days postoperatively. The clinical outcome was binary: success or failure (mortality or the need for repeated pleural intervention). RESULTS: The study group comprised fifty-two patients. The median C-reactive protein values were as follows: 146 mg/L (pre-operative), 134 mg/L (post-operative day 2), and 116 mg/L (post-operative day 7). There was a trend toward a decrease in these values during the first week after surgery, but this difference was only statistically significant on day 7 after surgery. Over the first week after surgery, the C-reactive protein values decreased similarly in both groups (successful and failed treatment). No correlation between the preoperative C-reactive protein level and the clinical outcome was found. CONCLUSIONS: We observed that, in contrast to other medical conditions, C-reactive protein levels fall slowly during the first postoperative week in patients who have undergone surgical treatment for pleural empyema. No correlation between the perioperative C-reactive protein level and the clinical outcome was observed.Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2012-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/19661DOI:10.6061/clinics/2012(03)07Clinics; Vol. 67 No. 3 (2012); 243-247Clinics; v. 67 n. 3 (2012); 243-247Clinics; Vol. 67 Núm. 3 (2012); 243-2471980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/19661/21725Medeiros, Israel LopesTerra, Ricardo MingariniChoi, Esther MihwaPego-Fernandes, Paulo ManuelJatene, Fabio Biscegliinfo:eu-repo/semantics/openAccess2012-05-24T18:49:10Zoai:revistas.usp.br:article/19661Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-24T18:49:10Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema |
title |
Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema |
spellingShingle |
Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema Medeiros, Israel Lopes Pleural Empyema C-Reactive Protein Treatment Outcome Surgery |
title_short |
Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema |
title_full |
Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema |
title_fullStr |
Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema |
title_full_unstemmed |
Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema |
title_sort |
Evaluation of serial C-reactive protein measurements after surgical treatment of pleural empyema |
author |
Medeiros, Israel Lopes |
author_facet |
Medeiros, Israel Lopes Terra, Ricardo Mingarini Choi, Esther Mihwa Pego-Fernandes, Paulo Manuel Jatene, Fabio Biscegli |
author_role |
author |
author2 |
Terra, Ricardo Mingarini Choi, Esther Mihwa Pego-Fernandes, Paulo Manuel Jatene, Fabio Biscegli |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Medeiros, Israel Lopes Terra, Ricardo Mingarini Choi, Esther Mihwa Pego-Fernandes, Paulo Manuel Jatene, Fabio Biscegli |
dc.subject.por.fl_str_mv |
Pleural Empyema C-Reactive Protein Treatment Outcome Surgery |
topic |
Pleural Empyema C-Reactive Protein Treatment Outcome Surgery |
description |
OBJECTIVE: Serial C-reactive protein measurements have been used to diagnose and monitor the response to therapy in patients with pneumonia and other infectious diseases. Nonetheless, the role of C-reactive protein measurement after surgical treatment for pleural empyema is not well defined. The aim of this study is to describe the behavior of C-reactive protein levels after the surgical treatment of pleural empyema and to correlate this parameter with the patient's prognosis. METHODS: We retrospectively analyzed the records of patients with pleural empyema treated by either chest-tube drainage or surgery from January 2006 to December 2008. C-reactive protein levels were recorded preoperatively and 2 and 7 days postoperatively. The clinical outcome was binary: success or failure (mortality or the need for repeated pleural intervention). RESULTS: The study group comprised fifty-two patients. The median C-reactive protein values were as follows: 146 mg/L (pre-operative), 134 mg/L (post-operative day 2), and 116 mg/L (post-operative day 7). There was a trend toward a decrease in these values during the first week after surgery, but this difference was only statistically significant on day 7 after surgery. Over the first week after surgery, the C-reactive protein values decreased similarly in both groups (successful and failed treatment). No correlation between the preoperative C-reactive protein level and the clinical outcome was found. CONCLUSIONS: We observed that, in contrast to other medical conditions, C-reactive protein levels fall slowly during the first postoperative week in patients who have undergone surgical treatment for pleural empyema. No correlation between the perioperative C-reactive protein level and the clinical outcome was observed. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/19661 DOI:10.6061/clinics/2012(03)07 |
url |
https://www.revistas.usp.br/clinics/article/view/19661 |
identifier_str_mv |
DOI:10.6061/clinics/2012(03)07 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/19661/21725 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 67 No. 3 (2012); 243-247 Clinics; v. 67 n. 3 (2012); 243-247 Clinics; Vol. 67 Núm. 3 (2012); 243-247 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222758213255168 |