Is brain banking of psychiatric cases valuable for neurobiological research?

Detalhes bibliográficos
Autor(a) principal: Schmitt, Andrea
Data de Publicação: 2008
Outros Autores: Parlapani, Eleni, Bauer, Manfred, Heinsen, Helmut, Falkai, Peter
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/17859
Resumo: It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized.
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spelling Is brain banking of psychiatric cases valuable for neurobiological research? Brain BankingPost MortemSchizophreniaBipolar DisorderNeurobiology It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1785910.1590/S1807-59322008000200015Clinics; Vol. 63 No. 2 (2008); 255-266 Clinics; v. 63 n. 2 (2008); 255-266 Clinics; Vol. 63 Núm. 2 (2008); 255-266 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/17859/19924Schmitt, AndreaParlapani, EleniBauer, ManfredHeinsen, HelmutFalkai, Peterinfo:eu-repo/semantics/openAccess2012-05-22T18:38:27Zoai:revistas.usp.br:article/17859Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-22T18:38:27Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Is brain banking of psychiatric cases valuable for neurobiological research?
title Is brain banking of psychiatric cases valuable for neurobiological research?
spellingShingle Is brain banking of psychiatric cases valuable for neurobiological research?
Schmitt, Andrea
Brain Banking
Post Mortem
Schizophrenia
Bipolar Disorder
Neurobiology
title_short Is brain banking of psychiatric cases valuable for neurobiological research?
title_full Is brain banking of psychiatric cases valuable for neurobiological research?
title_fullStr Is brain banking of psychiatric cases valuable for neurobiological research?
title_full_unstemmed Is brain banking of psychiatric cases valuable for neurobiological research?
title_sort Is brain banking of psychiatric cases valuable for neurobiological research?
author Schmitt, Andrea
author_facet Schmitt, Andrea
Parlapani, Eleni
Bauer, Manfred
Heinsen, Helmut
Falkai, Peter
author_role author
author2 Parlapani, Eleni
Bauer, Manfred
Heinsen, Helmut
Falkai, Peter
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Schmitt, Andrea
Parlapani, Eleni
Bauer, Manfred
Heinsen, Helmut
Falkai, Peter
dc.subject.por.fl_str_mv Brain Banking
Post Mortem
Schizophrenia
Bipolar Disorder
Neurobiology
topic Brain Banking
Post Mortem
Schizophrenia
Bipolar Disorder
Neurobiology
description It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/17859
10.1590/S1807-59322008000200015
url https://www.revistas.usp.br/clinics/article/view/17859
identifier_str_mv 10.1590/S1807-59322008000200015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/17859/19924
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 63 No. 2 (2008); 255-266
Clinics; v. 63 n. 2 (2008); 255-266
Clinics; Vol. 63 Núm. 2 (2008); 255-266
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
_version_ 1800222753978056704

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