Is brain banking of psychiatric cases valuable for neurobiological research?
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/17859 |
Resumo: | It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized. |
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Is brain banking of psychiatric cases valuable for neurobiological research? Brain BankingPost MortemSchizophreniaBipolar DisorderNeurobiology It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1785910.1590/S1807-59322008000200015Clinics; Vol. 63 No. 2 (2008); 255-266 Clinics; v. 63 n. 2 (2008); 255-266 Clinics; Vol. 63 Núm. 2 (2008); 255-266 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/17859/19924Schmitt, AndreaParlapani, EleniBauer, ManfredHeinsen, HelmutFalkai, Peterinfo:eu-repo/semantics/openAccess2012-05-22T18:38:27Zoai:revistas.usp.br:article/17859Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-22T18:38:27Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Is brain banking of psychiatric cases valuable for neurobiological research? |
title |
Is brain banking of psychiatric cases valuable for neurobiological research? |
spellingShingle |
Is brain banking of psychiatric cases valuable for neurobiological research? Schmitt, Andrea Brain Banking Post Mortem Schizophrenia Bipolar Disorder Neurobiology |
title_short |
Is brain banking of psychiatric cases valuable for neurobiological research? |
title_full |
Is brain banking of psychiatric cases valuable for neurobiological research? |
title_fullStr |
Is brain banking of psychiatric cases valuable for neurobiological research? |
title_full_unstemmed |
Is brain banking of psychiatric cases valuable for neurobiological research? |
title_sort |
Is brain banking of psychiatric cases valuable for neurobiological research? |
author |
Schmitt, Andrea |
author_facet |
Schmitt, Andrea Parlapani, Eleni Bauer, Manfred Heinsen, Helmut Falkai, Peter |
author_role |
author |
author2 |
Parlapani, Eleni Bauer, Manfred Heinsen, Helmut Falkai, Peter |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Schmitt, Andrea Parlapani, Eleni Bauer, Manfred Heinsen, Helmut Falkai, Peter |
dc.subject.por.fl_str_mv |
Brain Banking Post Mortem Schizophrenia Bipolar Disorder Neurobiology |
topic |
Brain Banking Post Mortem Schizophrenia Bipolar Disorder Neurobiology |
description |
It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/17859 10.1590/S1807-59322008000200015 |
url |
https://www.revistas.usp.br/clinics/article/view/17859 |
identifier_str_mv |
10.1590/S1807-59322008000200015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/17859/19924 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 63 No. 2 (2008); 255-266 Clinics; v. 63 n. 2 (2008); 255-266 Clinics; Vol. 63 Núm. 2 (2008); 255-266 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222753978056704 |