Composition, antioxidant properties, and biological activities of the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez.

• Autor(a) principal: Fabri, Natasha Tiemi
• Data de Publicação: 2019
• Outros Autores: Gatto, Larissa Junqueira, Furusho, Alethéia Santos, Garcia, Meira Janette Ballestros, Marques, Francisco de Assis, Miguel, Marilis Dallarmi, Montrucchio, Deise Prehs, Zanin, Sandra Maria Warumby, Miguel, Obdulio Gomes, Dias, Josiane de Fátima Gaspari
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Pharmaceutical Sciences
• Texto Completo: https://www.revistas.usp.br/bjps/article/view/181056
• topic: Ocotea diospyrifolia; Lauraceae; Spathulenol; Antioxidant; Toxicity

The article has aimed to characterize the essential oil extracted from Ocotea diospyrifolia (Meisn.) Mez. leaves, in terms of its chemical composition and antioxidant, hemolytic, and phytotoxic potentials, as well as its toxicity against Artemia salina. The major constituents identified by CG-MS were δ-elemene, spathulenol, and β-atlantol. When screened for potential biological activities, the essential oil presented low toxicity against Artemia salina, and a capacity of lysing red blood cells. Also, the evaluation of its in vitro antioxidant activity, using the phosphomolybdenum method, showed better results when compared to butylhydroxytoluene (BHT) and rutin. In conclusion, the results obtained showed certain in vitro toxicity, leading to an interesting target for cytotoxicity evaluations of carcinoma cells.