Iliac crest autograft in rabbit dorsolateral spinal fusion

Detalhes bibliográficos
Autor(a) principal: Silva, Alessandra S. Arreguy
Data de Publicação: 2004
Outros Autores: Del Carlo, Ricardo Junqueira, Rizzo, Damaris, Viloria, Marlene Isabel Vargas, Marchesis, Denise, Monteiro, Betânia Souza
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
Texto Completo: https://www.revistas.usp.br/bjvras/article/view/6285
Resumo: The effectiveness of the iliac crest autograft in dorsolateral spinal fusion promotion of the lumbar vertebral body L5-L6 was evaluated in 33 New Zealand White rabbits, distributed in two groups, with nine animals in group 1 (G1), submitted the bilateral transverse processes decortification; and twenty-four in group 2 (G2), which received 2g of iliac crest autograft on decortificed bilateral transverse processes. Three rabbits of G1 and eight of G2 were killed at 5, 7 and 9 weeks after surgery and submitted to palpation, X-ray and light microscopic evaluations. The fusion site of animals of G2 was submitted to biomechanic tests accomplished for evaluation of force and rigidity. All animals of G1 presented normal mobility of the segment operated in all moments of evaluation and they didn't present fusion evidence in X-ray analysis. In the light microscopic evaluations periosteal discreet reaction was observed, without evidence of bony bridge formation. In G2, evaluation for palpation and x-rays evidenced bone fusion to the 5 weeks, intensifying along the weeks. At 5 weeks, in the light microscopic analysis, reabsorption of bone fragments was observed, presence of trabecular bone and chondroides hearts, besides the abundant irrigation to the 7 weeks and osteointegration in every grafted bed to the 9 weeks, with bone endochondral formation prevailing. Force and rigidity increase of the fusion bone mass along the time of evaluation was observed in the biomechanic test.. When a comparison of the treated vertebrae and no treated was accomplished, the union indexes were larger in all of the moments, in the treated group. A high percentage of vertebral fusion was gotten when iliac crest autograft was used in rabbits.
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spelling Iliac crest autograft in rabbit dorsolateral spinal fusionAutoenxerto de crista ilíaca de coelhos na união vertebral dorsolateral lombarEnxerto ósseoArtrodeseColuna vertebralBone graftArthrodesisLombar spineThe effectiveness of the iliac crest autograft in dorsolateral spinal fusion promotion of the lumbar vertebral body L5-L6 was evaluated in 33 New Zealand White rabbits, distributed in two groups, with nine animals in group 1 (G1), submitted the bilateral transverse processes decortification; and twenty-four in group 2 (G2), which received 2g of iliac crest autograft on decortificed bilateral transverse processes. Three rabbits of G1 and eight of G2 were killed at 5, 7 and 9 weeks after surgery and submitted to palpation, X-ray and light microscopic evaluations. The fusion site of animals of G2 was submitted to biomechanic tests accomplished for evaluation of force and rigidity. All animals of G1 presented normal mobility of the segment operated in all moments of evaluation and they didn't present fusion evidence in X-ray analysis. In the light microscopic evaluations periosteal discreet reaction was observed, without evidence of bony bridge formation. In G2, evaluation for palpation and x-rays evidenced bone fusion to the 5 weeks, intensifying along the weeks. At 5 weeks, in the light microscopic analysis, reabsorption of bone fragments was observed, presence of trabecular bone and chondroides hearts, besides the abundant irrigation to the 7 weeks and osteointegration in every grafted bed to the 9 weeks, with bone endochondral formation prevailing. Force and rigidity increase of the fusion bone mass along the time of evaluation was observed in the biomechanic test.. When a comparison of the treated vertebrae and no treated was accomplished, the union indexes were larger in all of the moments, in the treated group. A high percentage of vertebral fusion was gotten when iliac crest autograft was used in rabbits.Foi realizada artrodese dorsolateral das vértebras lombares L5-L6 de coelhos, avaliando-se a eficácia do autoenxerto da crista ilíaca na promoção de união vertebral. Foram utilizados 33 coelhos da raça Nova Zelândia Branco, distribuídos em dois grupos, com nove indivíduos no grupo 1 (G1), submetidos a descorticação bilateral dos processos transversos; e vinte e quatro indivíduos no grupo 2 (G2), que receberam 2g de autoenxerto da crista ilíaca sobre a área de descorticação. Três coelhos do G1 e oito do G2 foram submetidos à eutanásia as cinco, sete e nove semanas após o ato operatório e à avaliações por palpação, radiográfica e histológica no local do procedimento. Testes biomecânicos para avaliação de força e rigidez da união foram realizados somente nos animais do G2 e as vértebras adjacentes não operadas, serviram de controle. Os animais do G1 apresentaram mobilidade normal à palpação do segmento operado em todos os momentos de avaliação e não apresentaram evidência radiográfica de união. Na avaliação histológica foi observada discreta reação periosteal, sem evidências de formação de ponte óssea. No G2, as avaliações por palpação e radiográficas evidenciaram indícios de união óssea as cinco semanas, intensificando-se ao longo das semanas de avaliação. Na análise histológica foi observada reabsorção de fragmentos ósseos as cinco semanas, predominância de trabéculas ósseas e corações condróides, além de suprimento sanguíneo abundante as sete semanas e osteointegração em todo leito de enxertia as nove semanas, com predomínio de formação óssea endocondral. Os testes biomecânicos evidenciaram aumento da força e rigidez da massa óssea ao longo do tempo de avaliação. Quando foi realizada comparação das vértebras tratadas e não tratadas, os índices de união foram maiores em todos os momentos, no grupo tratado. Com os resultados foi possível concluir que alta percentagem de união vertebral foi conseguida quando o osso autógeno da crista ilíaca foi utilizado como material de enxertia em coelhos.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia2004-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/628510.1590/S1413-95962004000400006Brazilian Journal of Veterinary Research and Animal Science; Vol. 41 Núm. 4 (2004); 254-260 Brazilian Journal of Veterinary Research and Animal Science; Vol. 41 No. 4 (2004); 254-260 Brazilian Journal of Veterinary Research and Animal Science; v. 41 n. 4 (2004); 254-260 Brazilian Journal of Veterinary Research and Animal Science; V. 41 N. 4 (2004); 254-260 1678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPporhttps://www.revistas.usp.br/bjvras/article/view/6285/7816Silva, Alessandra S. ArreguyDel Carlo, Ricardo JunqueiraRizzo, DamarisViloria, Marlene Isabel VargasMarchesis, DeniseMonteiro, Betânia Souzainfo:eu-repo/semantics/openAccess2020-06-23T04:29:19Zoai:revistas.usp.br:article/6285Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:42:35.572069Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false
dc.title.none.fl_str_mv Iliac crest autograft in rabbit dorsolateral spinal fusion
Autoenxerto de crista ilíaca de coelhos na união vertebral dorsolateral lombar
title Iliac crest autograft in rabbit dorsolateral spinal fusion
spellingShingle Iliac crest autograft in rabbit dorsolateral spinal fusion
Silva, Alessandra S. Arreguy
Enxerto ósseo
Artrodese
Coluna vertebral
Bone graft
Arthrodesis
Lombar spine
title_short Iliac crest autograft in rabbit dorsolateral spinal fusion
title_full Iliac crest autograft in rabbit dorsolateral spinal fusion
title_fullStr Iliac crest autograft in rabbit dorsolateral spinal fusion
title_full_unstemmed Iliac crest autograft in rabbit dorsolateral spinal fusion
title_sort Iliac crest autograft in rabbit dorsolateral spinal fusion
author Silva, Alessandra S. Arreguy
author_facet Silva, Alessandra S. Arreguy
Del Carlo, Ricardo Junqueira
Rizzo, Damaris
Viloria, Marlene Isabel Vargas
Marchesis, Denise
Monteiro, Betânia Souza
author_role author
author2 Del Carlo, Ricardo Junqueira
Rizzo, Damaris
Viloria, Marlene Isabel Vargas
Marchesis, Denise
Monteiro, Betânia Souza
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Alessandra S. Arreguy
Del Carlo, Ricardo Junqueira
Rizzo, Damaris
Viloria, Marlene Isabel Vargas
Marchesis, Denise
Monteiro, Betânia Souza
dc.subject.por.fl_str_mv Enxerto ósseo
Artrodese
Coluna vertebral
Bone graft
Arthrodesis
Lombar spine
topic Enxerto ósseo
Artrodese
Coluna vertebral
Bone graft
Arthrodesis
Lombar spine
description The effectiveness of the iliac crest autograft in dorsolateral spinal fusion promotion of the lumbar vertebral body L5-L6 was evaluated in 33 New Zealand White rabbits, distributed in two groups, with nine animals in group 1 (G1), submitted the bilateral transverse processes decortification; and twenty-four in group 2 (G2), which received 2g of iliac crest autograft on decortificed bilateral transverse processes. Three rabbits of G1 and eight of G2 were killed at 5, 7 and 9 weeks after surgery and submitted to palpation, X-ray and light microscopic evaluations. The fusion site of animals of G2 was submitted to biomechanic tests accomplished for evaluation of force and rigidity. All animals of G1 presented normal mobility of the segment operated in all moments of evaluation and they didn't present fusion evidence in X-ray analysis. In the light microscopic evaluations periosteal discreet reaction was observed, without evidence of bony bridge formation. In G2, evaluation for palpation and x-rays evidenced bone fusion to the 5 weeks, intensifying along the weeks. At 5 weeks, in the light microscopic analysis, reabsorption of bone fragments was observed, presence of trabecular bone and chondroides hearts, besides the abundant irrigation to the 7 weeks and osteointegration in every grafted bed to the 9 weeks, with bone endochondral formation prevailing. Force and rigidity increase of the fusion bone mass along the time of evaluation was observed in the biomechanic test.. When a comparison of the treated vertebrae and no treated was accomplished, the union indexes were larger in all of the moments, in the treated group. A high percentage of vertebral fusion was gotten when iliac crest autograft was used in rabbits.
publishDate 2004
dc.date.none.fl_str_mv 2004-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/6285
10.1590/S1413-95962004000400006
url https://www.revistas.usp.br/bjvras/article/view/6285
identifier_str_mv 10.1590/S1413-95962004000400006
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/6285/7816
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science; Vol. 41 Núm. 4 (2004); 254-260
Brazilian Journal of Veterinary Research and Animal Science; Vol. 41 No. 4 (2004); 254-260
Brazilian Journal of Veterinary Research and Animal Science; v. 41 n. 4 (2004); 254-260
Brazilian Journal of Veterinary Research and Animal Science; V. 41 N. 4 (2004); 254-260
1678-4456
1413-9596
reponame:Brazilian Journal of Veterinary Research and Animal Science
instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron:USP
instname_str Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Veterinary Research and Animal Science
collection Brazilian Journal of Veterinary Research and Animal Science
repository.name.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
repository.mail.fl_str_mv bjvras@usp.br
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