Bacterial Cellulose/Collagen Hydrogel for Wound Healing

Detalhes bibliográficos
Autor(a) principal: Moraes,Paula Rodrigues Fontes de Sousa
Data de Publicação: 2016
Outros Autores: Saska,Sybele, Barud,Hernane, Lima,Laís Roncalho de, Martins,Virgínia da Conceição Amaro, Plepis,Ana Maria de Guzzi, Ribeiro,Sidney José Lima, Gaspar,Ana Maria Minarelli
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Materials research (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392016000100106
Resumo: This study compares a wound dressing based on bacterial cellulose/collagen (BC/COL) hydrogel in rat dorsum with commercial collagenase ointment and untreated wound. The hydrogel was characterized by Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Fourier transformed - Infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). According to the In vivo test and macroscopic evaluation, BC/COL hydrogel showed a better repair of wounds and promoted statistically significant differences of tissue repair between treatments on the 7th day after surgery. Better quality, quantity and orientation evaluation of collagen fibers (p=0.0001) were observed in the BC/COL hydrogel and collagenase ointment groups in relation to the control group. The BC/COL hydrogel promoted better wound healing than collagenase and the control group, therefore, it can be considered a potential wound dressing for skin regeneration.
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spelling Bacterial Cellulose/Collagen Hydrogel for Wound Healingbacterial cellulosecollagenhydrogelwound dressingtissue repairThis study compares a wound dressing based on bacterial cellulose/collagen (BC/COL) hydrogel in rat dorsum with commercial collagenase ointment and untreated wound. The hydrogel was characterized by Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Fourier transformed - Infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). According to the In vivo test and macroscopic evaluation, BC/COL hydrogel showed a better repair of wounds and promoted statistically significant differences of tissue repair between treatments on the 7th day after surgery. Better quality, quantity and orientation evaluation of collagen fibers (p=0.0001) were observed in the BC/COL hydrogel and collagenase ointment groups in relation to the control group. The BC/COL hydrogel promoted better wound healing than collagenase and the control group, therefore, it can be considered a potential wound dressing for skin regeneration.ABM, ABC, ABPol2016-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392016000100106Materials Research v.19 n.1 2016reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/1980-5373-MR-2015-0249info:eu-repo/semantics/openAccessMoraes,Paula Rodrigues Fontes de SousaSaska,SybeleBarud,HernaneLima,Laís Roncalho deMartins,Virgínia da Conceição AmaroPlepis,Ana Maria de GuzziRibeiro,Sidney José LimaGaspar,Ana Maria Minarellieng2016-03-29T00:00:00Zoai:scielo:S1516-14392016000100106Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2016-03-29T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false
dc.title.none.fl_str_mv Bacterial Cellulose/Collagen Hydrogel for Wound Healing
title Bacterial Cellulose/Collagen Hydrogel for Wound Healing
spellingShingle Bacterial Cellulose/Collagen Hydrogel for Wound Healing
Moraes,Paula Rodrigues Fontes de Sousa
bacterial cellulose
collagen
hydrogel
wound dressing
tissue repair
title_short Bacterial Cellulose/Collagen Hydrogel for Wound Healing
title_full Bacterial Cellulose/Collagen Hydrogel for Wound Healing
title_fullStr Bacterial Cellulose/Collagen Hydrogel for Wound Healing
title_full_unstemmed Bacterial Cellulose/Collagen Hydrogel for Wound Healing
title_sort Bacterial Cellulose/Collagen Hydrogel for Wound Healing
author Moraes,Paula Rodrigues Fontes de Sousa
author_facet Moraes,Paula Rodrigues Fontes de Sousa
Saska,Sybele
Barud,Hernane
Lima,Laís Roncalho de
Martins,Virgínia da Conceição Amaro
Plepis,Ana Maria de Guzzi
Ribeiro,Sidney José Lima
Gaspar,Ana Maria Minarelli
author_role author
author2 Saska,Sybele
Barud,Hernane
Lima,Laís Roncalho de
Martins,Virgínia da Conceição Amaro
Plepis,Ana Maria de Guzzi
Ribeiro,Sidney José Lima
Gaspar,Ana Maria Minarelli
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Moraes,Paula Rodrigues Fontes de Sousa
Saska,Sybele
Barud,Hernane
Lima,Laís Roncalho de
Martins,Virgínia da Conceição Amaro
Plepis,Ana Maria de Guzzi
Ribeiro,Sidney José Lima
Gaspar,Ana Maria Minarelli
dc.subject.por.fl_str_mv bacterial cellulose
collagen
hydrogel
wound dressing
tissue repair
topic bacterial cellulose
collagen
hydrogel
wound dressing
tissue repair
description This study compares a wound dressing based on bacterial cellulose/collagen (BC/COL) hydrogel in rat dorsum with commercial collagenase ointment and untreated wound. The hydrogel was characterized by Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Fourier transformed - Infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). According to the In vivo test and macroscopic evaluation, BC/COL hydrogel showed a better repair of wounds and promoted statistically significant differences of tissue repair between treatments on the 7th day after surgery. Better quality, quantity and orientation evaluation of collagen fibers (p=0.0001) were observed in the BC/COL hydrogel and collagenase ointment groups in relation to the control group. The BC/COL hydrogel promoted better wound healing than collagenase and the control group, therefore, it can be considered a potential wound dressing for skin regeneration.
publishDate 2016
dc.date.none.fl_str_mv 2016-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392016000100106
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392016000100106
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1980-5373-MR-2015-0249
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv ABM, ABC, ABPol
publisher.none.fl_str_mv ABM, ABC, ABPol
dc.source.none.fl_str_mv Materials Research v.19 n.1 2016
reponame:Materials research (São Carlos. Online)
instname:Universidade Federal de São Carlos (UFSCAR)
instacron:ABM ABC ABPOL
instname_str Universidade Federal de São Carlos (UFSCAR)
instacron_str ABM ABC ABPOL
institution ABM ABC ABPOL
reponame_str Materials research (São Carlos. Online)
collection Materials research (São Carlos. Online)
repository.name.fl_str_mv Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)
repository.mail.fl_str_mv dedz@power.ufscar.br
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