Amyotrophic lateral sclerosis with dementia: case report

Detalhes bibliográficos
Autor(a) principal: BRITO-MARQUES,PAULO ROBERTO DE
Data de Publicação: 1999
Outros Autores: MELLO,ROBERTO VIEIRA DE
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000200018
Resumo: A patient is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis. A magnetic resonance imaging showed signs of frontal and especially left temporal atrophy. The pattern of dementia indicated impaired frontotemporal lobe functions, evidenced by reduced tracer uptake in the frontotemporal lobes on brain single photon emission computed tomography. Neuropathological examination in this patient revealed mild frontotemporal atrophy with spongiform changes and neuronal loss affecting mainly layers II and III of the frontotemporal cortices. There was atrophy of the hypoglossal nuclei. The spinal cord changes were consistent with motor neuron disease. The patient showed an irreversible and progressive course. A review of the relevant literature was made.
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spelling Amyotrophic lateral sclerosis with dementia: case reportdementiaamyotrophic lateral sclerosishypothyroidismbrain SPECTA patient is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis. A magnetic resonance imaging showed signs of frontal and especially left temporal atrophy. The pattern of dementia indicated impaired frontotemporal lobe functions, evidenced by reduced tracer uptake in the frontotemporal lobes on brain single photon emission computed tomography. Neuropathological examination in this patient revealed mild frontotemporal atrophy with spongiform changes and neuronal loss affecting mainly layers II and III of the frontotemporal cortices. There was atrophy of the hypoglossal nuclei. The spinal cord changes were consistent with motor neuron disease. The patient showed an irreversible and progressive course. A review of the relevant literature was made.Academia Brasileira de Neurologia - ABNEURO1999-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000200018Arquivos de Neuro-Psiquiatria v.57 n.2A 1999reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X1999000200018info:eu-repo/semantics/openAccessBRITO-MARQUES,PAULO ROBERTO DEMELLO,ROBERTO VIEIRA DEeng2000-12-06T00:00:00Zoai:scielo:S0004-282X1999000200018Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2000-12-06T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Amyotrophic lateral sclerosis with dementia: case report
title Amyotrophic lateral sclerosis with dementia: case report
spellingShingle Amyotrophic lateral sclerosis with dementia: case report
BRITO-MARQUES,PAULO ROBERTO DE
dementia
amyotrophic lateral sclerosis
hypothyroidism
brain SPECT
title_short Amyotrophic lateral sclerosis with dementia: case report
title_full Amyotrophic lateral sclerosis with dementia: case report
title_fullStr Amyotrophic lateral sclerosis with dementia: case report
title_full_unstemmed Amyotrophic lateral sclerosis with dementia: case report
title_sort Amyotrophic lateral sclerosis with dementia: case report
author BRITO-MARQUES,PAULO ROBERTO DE
author_facet BRITO-MARQUES,PAULO ROBERTO DE
MELLO,ROBERTO VIEIRA DE
author_role author
author2 MELLO,ROBERTO VIEIRA DE
author2_role author
dc.contributor.author.fl_str_mv BRITO-MARQUES,PAULO ROBERTO DE
MELLO,ROBERTO VIEIRA DE
dc.subject.por.fl_str_mv dementia
amyotrophic lateral sclerosis
hypothyroidism
brain SPECT
topic dementia
amyotrophic lateral sclerosis
hypothyroidism
brain SPECT
description A patient is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis. A magnetic resonance imaging showed signs of frontal and especially left temporal atrophy. The pattern of dementia indicated impaired frontotemporal lobe functions, evidenced by reduced tracer uptake in the frontotemporal lobes on brain single photon emission computed tomography. Neuropathological examination in this patient revealed mild frontotemporal atrophy with spongiform changes and neuronal loss affecting mainly layers II and III of the frontotemporal cortices. There was atrophy of the hypoglossal nuclei. The spinal cord changes were consistent with motor neuron disease. The patient showed an irreversible and progressive course. A review of the relevant literature was made.
publishDate 1999
dc.date.none.fl_str_mv 1999-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000200018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000200018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X1999000200018
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.57 n.2A 1999
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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