Amyotrophic lateral sclerosis with dementia: case report
Autor(a) principal: | |
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Data de Publicação: | 1999 |
Outros Autores: | |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000200018 |
Resumo: | A patient is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis. A magnetic resonance imaging showed signs of frontal and especially left temporal atrophy. The pattern of dementia indicated impaired frontotemporal lobe functions, evidenced by reduced tracer uptake in the frontotemporal lobes on brain single photon emission computed tomography. Neuropathological examination in this patient revealed mild frontotemporal atrophy with spongiform changes and neuronal loss affecting mainly layers II and III of the frontotemporal cortices. There was atrophy of the hypoglossal nuclei. The spinal cord changes were consistent with motor neuron disease. The patient showed an irreversible and progressive course. A review of the relevant literature was made. |
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Amyotrophic lateral sclerosis with dementia: case reportdementiaamyotrophic lateral sclerosishypothyroidismbrain SPECTA patient is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis. A magnetic resonance imaging showed signs of frontal and especially left temporal atrophy. The pattern of dementia indicated impaired frontotemporal lobe functions, evidenced by reduced tracer uptake in the frontotemporal lobes on brain single photon emission computed tomography. Neuropathological examination in this patient revealed mild frontotemporal atrophy with spongiform changes and neuronal loss affecting mainly layers II and III of the frontotemporal cortices. There was atrophy of the hypoglossal nuclei. The spinal cord changes were consistent with motor neuron disease. The patient showed an irreversible and progressive course. A review of the relevant literature was made.Academia Brasileira de Neurologia - ABNEURO1999-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000200018Arquivos de Neuro-Psiquiatria v.57 n.2A 1999reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X1999000200018info:eu-repo/semantics/openAccessBRITO-MARQUES,PAULO ROBERTO DEMELLO,ROBERTO VIEIRA DEeng2000-12-06T00:00:00Zoai:scielo:S0004-282X1999000200018Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2000-12-06T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Amyotrophic lateral sclerosis with dementia: case report |
title |
Amyotrophic lateral sclerosis with dementia: case report |
spellingShingle |
Amyotrophic lateral sclerosis with dementia: case report BRITO-MARQUES,PAULO ROBERTO DE dementia amyotrophic lateral sclerosis hypothyroidism brain SPECT |
title_short |
Amyotrophic lateral sclerosis with dementia: case report |
title_full |
Amyotrophic lateral sclerosis with dementia: case report |
title_fullStr |
Amyotrophic lateral sclerosis with dementia: case report |
title_full_unstemmed |
Amyotrophic lateral sclerosis with dementia: case report |
title_sort |
Amyotrophic lateral sclerosis with dementia: case report |
author |
BRITO-MARQUES,PAULO ROBERTO DE |
author_facet |
BRITO-MARQUES,PAULO ROBERTO DE MELLO,ROBERTO VIEIRA DE |
author_role |
author |
author2 |
MELLO,ROBERTO VIEIRA DE |
author2_role |
author |
dc.contributor.author.fl_str_mv |
BRITO-MARQUES,PAULO ROBERTO DE MELLO,ROBERTO VIEIRA DE |
dc.subject.por.fl_str_mv |
dementia amyotrophic lateral sclerosis hypothyroidism brain SPECT |
topic |
dementia amyotrophic lateral sclerosis hypothyroidism brain SPECT |
description |
A patient is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis. A magnetic resonance imaging showed signs of frontal and especially left temporal atrophy. The pattern of dementia indicated impaired frontotemporal lobe functions, evidenced by reduced tracer uptake in the frontotemporal lobes on brain single photon emission computed tomography. Neuropathological examination in this patient revealed mild frontotemporal atrophy with spongiform changes and neuronal loss affecting mainly layers II and III of the frontotemporal cortices. There was atrophy of the hypoglossal nuclei. The spinal cord changes were consistent with motor neuron disease. The patient showed an irreversible and progressive course. A review of the relevant literature was made. |
publishDate |
1999 |
dc.date.none.fl_str_mv |
1999-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000200018 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000200018 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X1999000200018 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.57 n.2A 1999 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212751490678784 |