Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren

Detalhes bibliográficos
Autor(a) principal: Botelho, Anne Jardim
Data de Publicação: 2008
Outros Autores: Raff, Sophia, Rodrigues, Renato de Avila, Hoffman, Heather J., Diemert, David Joseph, Oliveira, Rodrigo Corrêa de, Bethony, Jeffrey Michael, Gazzinelli, Maria Flavia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/50560
Resumo: BILL AND MELINDA GATES FOUNDATION
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spelling Botelho, Anne JardimRaff, SophiaRodrigues, Renato de AvilaHoffman, Heather J.Diemert, David JosephOliveira, Rodrigo Corrêa deBethony, Jeffrey MichaelGazzinelli, Maria Flavia2021-12-29T14:04:12Z2021-12-29T14:04:12Z2008BOTELHO, Anne Jardim et al. Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren. Tropical Medicine and International Health, v. 13, n. 8, p. 994-1004, 2008. doi:10.1111/j.1365-3156.2008.02103.x1360-2276https://www.arca.fiocruz.br/handle/icict/5056010.1111/j.1365-3156.2008.02103.xBILL AND MELINDA GATES FOUNDATIONFundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Hospital das Clínicas. Setor de Nutrição e Dietética. Belo Horizonte, MG, BrazilDepartment of Microbiology, George Washington University, Immunology and Tropical Medicine, Washington DC, USA/ Department of Epidemiology and Biostatistics, George Washington University, Washington DC, USAFundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, BrazilDepartment of Epidemiology and Biostatistics, George Washington University, Washington DC, USADepartment of Microbiology, George Washington University, Immunology and Tropical Medicine, Washington DC, USA/Sabin Vaccine Institute. Washington DC, USAFundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, Brazil/Department of Microbiology, George Washington University, Immunology and Tropical Medicine, Washington DC, USAUniversidade Federal de Minas Gerais. Escola de Enfermagem. Belo Horizonte, MG, BrazilOBJECTIVE To investigate the relationship between hookworm and Ascaris lumbricoides infection and performance on three subsets of the Wechsler Intelligence Scale for Children - third edition (WISC-III) (Digit Span, Arithmetic and Coding) and Raven Colored Progressive Matrices. METHODS Cross-sectional study of 210 children between the ages of 6 and 11 years in Americaninhas, Minas Gerais, Brazil. Separate proportional odds models were used to measure the association between the intensity of helminth infections and poor performance on each of the four cognitive tests. RESULTS After adjusting for sex, age, socioeconomic status and other helminth infections, moderate-to-high-intensity hookworm infection was associated with poor performance on the WISC-III Coding subtest [OR = 3.20; 95% confidence interval (CI) = 1.43-7.17], low intensity of hookworm infection was associated with poor performance on the WISC-III Coding subtest [odds ratio (OR) = 3.71; 95% CI = 1.80-7.66] and moderate-to-high-intensity A. lumbricoides infection was associated with poor performance on the Raven test (OR = 2.03; 95% CI = 1.04-3.99), all in comparison with uninfected children. Children co-infected with A. lumbricoides infection and hookworm infection had greater odds of poor performance on some WISC-III subtests than children with only A. lumbricoides infection. CONCLUSIONS These findings suggest that hookworm infection may be associated with poorer concentration and information processing skills, as measured on the WISC-III Coding subtest, and that A. lumbricoides infection may be associated with poorer general intelligence, as measured through the Raven Colored Progressive Matrices. This study also presents evidence that polyparasitized children experience worse cognitive outcomes than children with only one helminth infectionengBlackwell PublishingHookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildrenAnkylostome, infection à A. lumbricoides et polyparasitisme associés à une mauvaise performance cognitive chez des écoliers brésiliensAnquilostoma, infección por A. lumbricoides y poliparasitismo asociado con un desempeño cognitivo pobre en niños escolares en Brasilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehookwormAscaris lumbricoidescognitive functionpolyparasitismschool childrenBrazilinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/50560/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALTropical Med Int Health - 2008 - Jardim‐Botelho - Hookworm Ascaris lumbricoides infection and polyparasitism associated.pdfTropical Med Int Health - 2008 - Jardim‐Botelho - Hookworm Ascaris lumbricoides infection and polyparasitism associated.pdfapplication/pdf86154https://www.arca.fiocruz.br/bitstream/icict/50560/2/Tropical%20Med%20Int%20Health%20-%202008%20-%20Jardim%e2%80%90Botelho%20-%20Hookworm%20%20Ascaris%20lumbricoides%20infection%20and%20polyparasitism%20associated.pdfc2db7868976f36ad9439f7cb3934d7eaMD52icict/505602021-12-29 11:04:12.023oai:www.arca.fiocruz.br:icict/50560Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-12-29T14:04:12Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren
dc.title.alternative.pt_BR.fl_str_mv Ankylostome, infection à A. lumbricoides et polyparasitisme associés à une mauvaise performance cognitive chez des écoliers brésiliens
Anquilostoma, infección por A. lumbricoides y poliparasitismo asociado con un desempeño cognitivo pobre en niños escolares en Brasil
title Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren
spellingShingle Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren
Botelho, Anne Jardim
hookworm
Ascaris lumbricoides
cognitive function
polyparasitism
school children
Brazil
title_short Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren
title_full Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren
title_fullStr Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren
title_full_unstemmed Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren
title_sort Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren
author Botelho, Anne Jardim
author_facet Botelho, Anne Jardim
Raff, Sophia
Rodrigues, Renato de Avila
Hoffman, Heather J.
Diemert, David Joseph
Oliveira, Rodrigo Corrêa de
Bethony, Jeffrey Michael
Gazzinelli, Maria Flavia
author_role author
author2 Raff, Sophia
Rodrigues, Renato de Avila
Hoffman, Heather J.
Diemert, David Joseph
Oliveira, Rodrigo Corrêa de
Bethony, Jeffrey Michael
Gazzinelli, Maria Flavia
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Botelho, Anne Jardim
Raff, Sophia
Rodrigues, Renato de Avila
Hoffman, Heather J.
Diemert, David Joseph
Oliveira, Rodrigo Corrêa de
Bethony, Jeffrey Michael
Gazzinelli, Maria Flavia
dc.subject.en.pt_BR.fl_str_mv hookworm
Ascaris lumbricoides
cognitive function
polyparasitism
school children
Brazil
topic hookworm
Ascaris lumbricoides
cognitive function
polyparasitism
school children
Brazil
description BILL AND MELINDA GATES FOUNDATION
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2021-12-29T14:04:12Z
dc.date.available.fl_str_mv 2021-12-29T14:04:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv BOTELHO, Anne Jardim et al. Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren. Tropical Medicine and International Health, v. 13, n. 8, p. 994-1004, 2008. doi:10.1111/j.1365-3156.2008.02103.x
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/50560
dc.identifier.issn.pt_BR.fl_str_mv 1360-2276
dc.identifier.doi.none.fl_str_mv 10.1111/j.1365-3156.2008.02103.x
identifier_str_mv BOTELHO, Anne Jardim et al. Hookworm, Ascaris lumbricoides infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren. Tropical Medicine and International Health, v. 13, n. 8, p. 994-1004, 2008. doi:10.1111/j.1365-3156.2008.02103.x
1360-2276
10.1111/j.1365-3156.2008.02103.x
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dc.publisher.none.fl_str_mv Blackwell Publishing
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