Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results

Detalhes bibliográficos
Autor(a) principal: Mendonca, Vanessa Amaral
Data de Publicação: 2008
Outros Autores: Teixeira, Antônio Lúcio, Melo, Gustavo Eustáquio Brito Alvim de, Teixeira, Mauro Martins, Martins Filho, Olindo Assis, Antunes, Carlos Maurício
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/55155
Resumo: Neste estudo, a expressão de receptores de quimiocinas na superfície dos leucócitos circulantes foi feita pela citometria de fluxo. Houve aumento da porcentagem de linfócitos CCR2+CD4+ no sangue periférico dos pacientes com hanseníase. Este resultado preliminar sugeriu alteração do perfil dos receptores de quimiocinas desses pacientes.
id CRUZ_0454037a82b4f5f4af67eb6c666c010b
oai_identifier_str oai:www.arca.fiocruz.br:icict/55155
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Mendonca, Vanessa AmaralTeixeira, Antônio LúcioMelo, Gustavo Eustáquio Brito Alvim deTeixeira, Mauro MartinsMartins Filho, Olindo AssisAntunes, Carlos MaurícioTeixeira, Antônio Lúcio2022-10-14T18:38:39Z2022-10-14T18:38:39Z2008MENDONÇA, Vanessa Amaral et al. Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results. Rev Soc Bras Med Trop., v. 41, Suppl 2, p. 95-98, 2008. doi: 10.1590/s0037-86822008000700019.0037-8682https://www.arca.fiocruz.br/handle/icict/5515510.1590/S0037-86822008000700019Neste estudo, a expressão de receptores de quimiocinas na superfície dos leucócitos circulantes foi feita pela citometria de fluxo. Houve aumento da porcentagem de linfócitos CCR2+CD4+ no sangue periférico dos pacientes com hanseníase. Este resultado preliminar sugeriu alteração do perfil dos receptores de quimiocinas desses pacientes.In this study, the expression of chemokine receptors on the surface of circulating leukocytes was determined using flow cytometry. An increase in the percentage of CCR2+CD4+ lymphocytes was observed in the peripheral blood of leprosy patients. This preliminary data suggests that alterations occur in die chemokine receptor profile of these patientsUniversidade Federal dos Vales de Jequitinhonha e Mucuri. Diamantina, MG, BrasilUniversidade Federal dos Vales de Jequitinhonha e Mucuri. Diamantina, MG, BrasilUniversidade Federal de Minas Gerais. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Belo Horizonte, MG, BrasilengSociedade Brasileira de Medicina TropicalHanseníaseReceptores de quimiocinaLeucócitosCitometria de fluxoLeprosyChemokine receptorsLeukocytesFlow cytometryAnalysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary resultsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALindex.pdfindex.pdfapplication/pdf199735https://www.arca.fiocruz.br/bitstream/icict/55155/2/index.pdfdbbca32bdebf9799dc08cbdaee8bbe0dMD52LICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/55155/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51icict/551552022-10-14 15:38:40.793oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-10-14T18:38:40Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
title Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
spellingShingle Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
Mendonca, Vanessa Amaral
Hanseníase
Receptores de quimiocina
Leucócitos
Citometria de fluxo
Leprosy
Chemokine receptors
Leukocytes
Flow cytometry
title_short Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
title_full Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
title_fullStr Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
title_full_unstemmed Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
title_sort Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
author Mendonca, Vanessa Amaral
author_facet Mendonca, Vanessa Amaral
Teixeira, Antônio Lúcio
Melo, Gustavo Eustáquio Brito Alvim de
Teixeira, Mauro Martins
Martins Filho, Olindo Assis
Antunes, Carlos Maurício
author_role author
author2 Teixeira, Antônio Lúcio
Melo, Gustavo Eustáquio Brito Alvim de
Teixeira, Mauro Martins
Martins Filho, Olindo Assis
Antunes, Carlos Maurício
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Mendonca, Vanessa Amaral
Teixeira, Antônio Lúcio
Melo, Gustavo Eustáquio Brito Alvim de
Teixeira, Mauro Martins
Martins Filho, Olindo Assis
Antunes, Carlos Maurício
Teixeira, Antônio Lúcio
dc.subject.other.en_US.fl_str_mv Hanseníase
Receptores de quimiocina
Leucócitos
Citometria de fluxo
topic Hanseníase
Receptores de quimiocina
Leucócitos
Citometria de fluxo
Leprosy
Chemokine receptors
Leukocytes
Flow cytometry
dc.subject.en.en_US.fl_str_mv Leprosy
Chemokine receptors
Leukocytes
Flow cytometry
description Neste estudo, a expressão de receptores de quimiocinas na superfície dos leucócitos circulantes foi feita pela citometria de fluxo. Houve aumento da porcentagem de linfócitos CCR2+CD4+ no sangue periférico dos pacientes com hanseníase. Este resultado preliminar sugeriu alteração do perfil dos receptores de quimiocinas desses pacientes.
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2022-10-14T18:38:39Z
dc.date.available.fl_str_mv 2022-10-14T18:38:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MENDONÇA, Vanessa Amaral et al. Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results. Rev Soc Bras Med Trop., v. 41, Suppl 2, p. 95-98, 2008. doi: 10.1590/s0037-86822008000700019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/55155
dc.identifier.issn.en_US.fl_str_mv 0037-8682
dc.identifier.doi.none.fl_str_mv 10.1590/S0037-86822008000700019
identifier_str_mv MENDONÇA, Vanessa Amaral et al. Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results. Rev Soc Bras Med Trop., v. 41, Suppl 2, p. 95-98, 2008. doi: 10.1590/s0037-86822008000700019.
0037-8682
10.1590/S0037-86822008000700019
url https://www.arca.fiocruz.br/handle/icict/55155
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/55155/2/index.pdf
https://www.arca.fiocruz.br/bitstream/icict/55155/1/license.txt
bitstream.checksum.fl_str_mv dbbca32bdebf9799dc08cbdaee8bbe0d
8a4605be74aa9ea9d79846c1fba20a33
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813008978328682496

Registros relacionados