Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach

Detalhes bibliográficos
Autor(a) principal: Robert, Anny Waloski
Data de Publicação: 2020
Outros Autores: Marcon, Bruna Hilzendeger, Dallagiovanna, Bruno
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/42738
Resumo: Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.
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spelling Robert, Anny WaloskiMarcon, Bruna HilzendegerDallagiovanna, Bruno2020-08-12T21:39:59Z2020-08-12T21:39:59Z2020ROBERT, Anny Waloski et al. Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach. Front. Cell Dev. Biol., v. 8, n. 561, p. 1-27, 2020.2296-634Xhttps://www.arca.fiocruz.br/handle/icict/4273810.3389/fcell.2020.00561por2296-634XTranscriptome ProfilingGene Expression ProfilingAdipogenesisOsteogenesisChondrogenesisMesenchymal Stem CellsCell DifferentiationPerfilación de la Expresión GénicaAdipogénesisOsteogénesisCondrogénesisCélulas Madre MesenquimatosasDiferenciación CelularAdipogenèseOstéogenèseChondrogenèseCellules souches mésenchymateusesDifférenciation cellulairePerfilação da Expressão GênicaAdipogeniaOsteogêneseCondrogêneseCélulas-Tronco MesenquimaisDiferenciação CelularAdipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approachinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Adipogenesis, osteogenesis and chondrogenesis of human mesenchymal stem/stromal cells (MSC) are complex and highly regulated processes. Over the years, several studies have focused on understanding the mechanisms involved in the MSC commitment to the osteogenic, adipogenic and/or chondrogenic phenotypes. High-throughput methodologies have been used to investigate the gene expression profile during differentiation. Association of data analysis of mRNAs, microRNAs, circular RNAs and long non-coding RNAs, obtained at different time points over these processes, are important to depict the complexity of differentiation. This review will discuss the results that were highlighted in transcriptome analyses of MSC undergoing adipogenic, osteogenic and chondrogenic differentiation. The focus is to shed light on key molecules, main signaling pathways and biological processes related to different time points of adipogenesis, osteogenesis and chondrogenesis.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83084https://www.arca.fiocruz.br/bitstream/icict/42738/1/license.txt783568c2893d2e25a99990b126be1772MD51ORIGINALfcell-08-00561ok.pdffcell-08-00561ok.pdfapplication/pdf1356552https://www.arca.fiocruz.br/bitstream/icict/42738/2/fcell-08-00561ok.pdf8b52f56bd3621f1ba78fdb2e5981ce92MD52TEXTfcell-08-00561ok.pdf.txtfcell-08-00561ok.pdf.txtExtracted texttext/plain144058https://www.arca.fiocruz.br/bitstream/icict/42738/3/fcell-08-00561ok.pdf.txt3c20fd3ed1a4257ab18b814485278017MD53icict/427382020-08-13 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dc.title.pt_BR.fl_str_mv Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach
title Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach
spellingShingle Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach
Robert, Anny Waloski
Transcriptome Profiling
Gene Expression Profiling
Adipogenesis
Osteogenesis
Chondrogenesis
Mesenchymal Stem Cells
Cell Differentiation
Perfilación de la Expresión Génica
Adipogénesis
Osteogénesis
Condrogénesis
Células Madre Mesenquimatosas
Diferenciación Celular
Adipogenèse
Ostéogenèse
Chondrogenèse
Cellules souches mésenchymateuses
Différenciation cellulaire
Perfilação da Expressão Gênica
Adipogenia
Osteogênese
Condrogênese
Células-Tronco Mesenquimais
Diferenciação Celular
title_short Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach
title_full Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach
title_fullStr Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach
title_full_unstemmed Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach
title_sort Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach
author Robert, Anny Waloski
author_facet Robert, Anny Waloski
Marcon, Bruna Hilzendeger
Dallagiovanna, Bruno
author_role author
author2 Marcon, Bruna Hilzendeger
Dallagiovanna, Bruno
author2_role author
author
dc.contributor.author.fl_str_mv Robert, Anny Waloski
Marcon, Bruna Hilzendeger
Dallagiovanna, Bruno
dc.subject.other.pt_BR.fl_str_mv Transcriptome Profiling
topic Transcriptome Profiling
Gene Expression Profiling
Adipogenesis
Osteogenesis
Chondrogenesis
Mesenchymal Stem Cells
Cell Differentiation
Perfilación de la Expresión Génica
Adipogénesis
Osteogénesis
Condrogénesis
Células Madre Mesenquimatosas
Diferenciación Celular
Adipogenèse
Ostéogenèse
Chondrogenèse
Cellules souches mésenchymateuses
Différenciation cellulaire
Perfilação da Expressão Gênica
Adipogenia
Osteogênese
Condrogênese
Células-Tronco Mesenquimais
Diferenciação Celular
dc.subject.en.pt_BR.fl_str_mv Gene Expression Profiling
Adipogenesis
Osteogenesis
Chondrogenesis
Mesenchymal Stem Cells
Cell Differentiation
dc.subject.es.pt_BR.fl_str_mv Perfilación de la Expresión Génica
Adipogénesis
Osteogénesis
Condrogénesis
Células Madre Mesenquimatosas
Diferenciación Celular
dc.subject.fr.pt_BR.fl_str_mv Adipogenèse
Ostéogenèse
Chondrogenèse
Cellules souches mésenchymateuses
Différenciation cellulaire
dc.subject.decs.pt_BR.fl_str_mv Perfilação da Expressão Gênica
Adipogenia
Osteogênese
Condrogênese
Células-Tronco Mesenquimais
Diferenciação Celular
description Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-08-12T21:39:59Z
dc.date.available.fl_str_mv 2020-08-12T21:39:59Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ROBERT, Anny Waloski et al. Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach. Front. Cell Dev. Biol., v. 8, n. 561, p. 1-27, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/42738
dc.identifier.issn.pt_BR.fl_str_mv 2296-634X
dc.identifier.eissn.none.fl_str_mv 10.3389/fcell.2020.00561
identifier_str_mv ROBERT, Anny Waloski et al. Adipogenesis, osteogenesis, and chondrogenesis of human mesenchymal stem/stromal cells: a comparative transcriptome approach. Front. Cell Dev. Biol., v. 8, n. 561, p. 1-27, 2020.
2296-634X
10.3389/fcell.2020.00561
url https://www.arca.fiocruz.br/handle/icict/42738
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv 2296-634X
publisher.none.fl_str_mv 2296-634X
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/42738/1/license.txt
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