Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/27055 |
Resumo: | Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil |
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Baro, BarbaraDeroost, KatrienRaiol, TaináBrito, MarceloAlmeida, Anne C. G.Menezes Neto, Armando deFigueiredo, Erick F. G.Alencar, AlineLeitão, RodrigoVal, FernandoMonteiro, Wuelton MarceloOliveira, AnnaArmengol, Maria del PilarFernández-Becerra, CarmenLacerda, Marcus V.del Portillo, Hernando A.2018-06-22T14:08:25Z2018-06-22T14:08:25Z2017BARO, Barbara et al. Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile. PLoS Negl Trop Dis., v. 11, n. 4, e0005365, 20171935-2727https://www.arca.fiocruz.br/handle/icict/2705510.1371/journal.pntd.0005365engPublic Library of SciencePlasmodiumsanguePlasmodiumBloodBone marrowGametocytesParasitic diseasesBone marrow cellsErythropoiesisMicroRNAsPlasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profileinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, BrazilFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, BrazilFundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, BrazilFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, BrazilFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil/Universidade do Estado do Amazonas. Manaus, AM, BrazilFundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil/ISGlobal. Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat de Barcelona. Barcelona, SpainFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, BrazilFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, BrazilFundação Hospitalar de Hematologia e Hematoterapia do Amazonas. Manaus, AM, BrazilFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil/Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, BrazilFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil/Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, BrazilInstitut d’Investigació Germans Trias i Pujol. Badalona, SpainInstitut d’Investigació Germans Trias i Pujol. Badalona, SpainISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB). Hospital Clínic - Universitat de Barcelona, Barcelona. Spain/Institut d’Investigació Germans Trias i Pujol. Badalona, SpainFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil/Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, BrazilISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB). Hospital Clínic - Universitat de Barcelona, Barcelona. Spain/Institut d’Investigació Germans Trias i Pujol. Badalona, SpainPlasmodium vivax is the most widely distributed human malaria parasite and responsible for large amounts of disease and burden [1]. The presence of P. vivax in the bone marrow was first noticed in the late 19th century [2], and examinations of sternal bone marrow aspirates were performed as an accessory to examinations of peripheral blood in malaria, including P. vivax [3]. Since then, little progress has been made in studying P. vivax infections in this tissue. One report explored accumulation of dyserythropoietic cells in anaemic infected patients [4]. In addition, two case studies reported P. vivax infections after autologous bone marrow transplantation [5][6], and a third one documented an accidental P. vivax infection due to bone marrow transplantation between a malaria-infected donor and a malaria-free receptor [7]. In Brazil, one patient with persistent thrombocytopaenia and an enlarged spleen was diagnosed with chronic P. vivax malaria after the finding of schizonts in the bone marrow aspirate [8]. In all these reports and case studies, however, parasite loads and life stages found in the bone marrow were not investigated, and no molecular tools were available to rule out mixed infections or to characterize specific parasite stages.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/27055/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALPlasmodium vivax gametocytes in the bone.pdfPlasmodium vivax gametocytes in the bone.pdfapplication/pdf988554https://www.arca.fiocruz.br/bitstream/icict/27055/2/Plasmodium%20vivax%20gametocytes%20in%20the%20bone.pdfa068ef0cc8f9157f4c8e231ee691d829MD52TEXTPlasmodium vivax gametocytes in the bone.pdf.txtPlasmodium vivax gametocytes in the bone.pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile |
| title |
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile |
| spellingShingle |
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile Baro, Barbara Plasmodium sangue Plasmodium Blood Bone marrow Gametocytes Parasitic diseases Bone marrow cells Erythropoiesis MicroRNAs |
| title_short |
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile |
| title_full |
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile |
| title_fullStr |
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile |
| title_full_unstemmed |
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile |
| title_sort |
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile |
| author |
Baro, Barbara |
| author_facet |
Baro, Barbara Deroost, Katrien Raiol, Tainá Brito, Marcelo Almeida, Anne C. G. Menezes Neto, Armando de Figueiredo, Erick F. G. Alencar, Aline Leitão, Rodrigo Val, Fernando Monteiro, Wuelton Marcelo Oliveira, Anna Armengol, Maria del Pilar Fernández-Becerra, Carmen Lacerda, Marcus V. del Portillo, Hernando A. |
| author_role |
author |
| author2 |
Deroost, Katrien Raiol, Tainá Brito, Marcelo Almeida, Anne C. G. Menezes Neto, Armando de Figueiredo, Erick F. G. Alencar, Aline Leitão, Rodrigo Val, Fernando Monteiro, Wuelton Marcelo Oliveira, Anna Armengol, Maria del Pilar Fernández-Becerra, Carmen Lacerda, Marcus V. del Portillo, Hernando A. |
| author2_role |
author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Baro, Barbara Deroost, Katrien Raiol, Tainá Brito, Marcelo Almeida, Anne C. G. Menezes Neto, Armando de Figueiredo, Erick F. G. Alencar, Aline Leitão, Rodrigo Val, Fernando Monteiro, Wuelton Marcelo Oliveira, Anna Armengol, Maria del Pilar Fernández-Becerra, Carmen Lacerda, Marcus V. del Portillo, Hernando A. |
| dc.subject.other.pt_BR.fl_str_mv |
Plasmodium sangue |
| topic |
Plasmodium sangue Plasmodium Blood Bone marrow Gametocytes Parasitic diseases Bone marrow cells Erythropoiesis MicroRNAs |
| dc.subject.en.pt_BR.fl_str_mv |
Plasmodium Blood Bone marrow Gametocytes Parasitic diseases Bone marrow cells Erythropoiesis MicroRNAs |
| description |
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil |
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2017 |
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2017 |
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2018-06-22T14:08:25Z |
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2018-06-22T14:08:25Z |
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info:eu-repo/semantics/article |
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article |
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| dc.identifier.citation.fl_str_mv |
BARO, Barbara et al. Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile. PLoS Negl Trop Dis., v. 11, n. 4, e0005365, 2017 |
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https://www.arca.fiocruz.br/handle/icict/27055 |
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1935-2727 |
| dc.identifier.doi.none.fl_str_mv |
10.1371/journal.pntd.0005365 |
| identifier_str_mv |
BARO, Barbara et al. Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile. PLoS Negl Trop Dis., v. 11, n. 4, e0005365, 2017 1935-2727 10.1371/journal.pntd.0005365 |
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