Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis

Detalhes bibliográficos
Autor(a) principal: Marzochi, Mauro Célio de Almeida
Data de Publicação: 2021
Outros Autores: Marzochi, Keyla Belizia Feldman, Fagundes, Aline, Schubach, Armando de Oliveira, Miranda, Luciana de Freitas Campos, Pacheco, Raquel da Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/50473
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
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spelling Marzochi, Mauro Célio de AlmeidaMarzochi, Keyla Belizia FeldmanFagundes, AlineSchubach, Armando de OliveiraMiranda, Luciana de Freitas CamposPacheco, Raquel da Silva2021-12-17T12:57:08Z2021-12-17T12:57:08Z2021MARZOCHI, Mauro Célio de Almeida et al. Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis. Frontiers in Tropical Diseases, v. 2, n. 723017, p. 1-9, 2021.2673-7515https://www.arca.fiocruz.br/handle/icict/5047310.3389/fitd.2021.723017engFrontiers MediaAnthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.There are several gaps in our knowledge on the origin and spread of Leishmania (Viannia) braziliensis, an etiological agent of cutaneous and mucocutaneous or American tegumentary leishmaniasis, to different biomes, hosts, and vectors, with important epidemiological implications, including the possible existence of an anthroponotic component. Historical, biological, and epidemiological evidence suggests that Leishmania (V.) braziliensis and its variants were preexistent in Amazonia with great genetic variability, where they dispersed with less variability to other regions (clonal expansion). During pre-Columbian times the parasite may have been transported by migrating humans and probably also their dogs, from western Amazonia to the high interAndean valleys and from there to other regions of South America. The same thing could have happened later, in the same way, when it spread to non-Amazonian regions of Brazil and other countries of South and Central America, between the late 19th and early 20th centuries, during the so-called Rubber Boom and construction of the Madeira-Mamoré Railway in the Brazilian Amazon, by migrant workers who later returned to their places of origin, transporting the agent. The parasite’s dispersal in genetic correlated clusters, involving unexpectedly distinct ecosystems in Brazil (Amazonian, Cerrado, Caatinga and Atlantic Forest biomes), has continued until the present through human displacement. The infection of certain species of domestic, synanthropic and even wild animals, could be secondary to anthropogenic introduction of L. (V.) braziliensis in new environments. We admit the same phenomena happening in the probable transference of Leishmania infantum (visceral leishmaniasis), and of Yersinia pestis (plague) from the Old world to the New world, generating domestic and wild enzotic cycles from these agents. These assumptions associated with human infections, chronicity and parasite persistence with possibility of recovery of Leishmania in peripheral blood, skin and scars of cured or asymptomatic patients, (that may provide an alternative blood meal), along with the sand flies’ adaptation to the peri-domicile and the high susceptibility of domestic dogs, horses, mules and cats to the parasite, can reinforce the evidence of anthropogenic spread of L. (V.) braziliensis.Leishmania (Viannia) braziliensisMucocutaneous leishmaniasisParasite persistenceHuman migrationsDogsExpansion in the AmericasAnthroponosisControlinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://www.arca.fiocruz.br/bitstream/icict/50473/1/license.txt586c046dcfeef936e32f0323bb9a47c0MD51ORIGINALAnthropogenic_Aline_Fagundes_etal_INI_2021.pdfAnthropogenic_Aline_Fagundes_etal_INI_2021.pdfapplication/pdf600347https://www.arca.fiocruz.br/bitstream/icict/50473/2/Anthropogenic_Aline_Fagundes_etal_INI_2021.pdfd75c71570af184e76eae292b6099a913MD52icict/504732021-12-21 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dc.title.pt_BR.fl_str_mv Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis
title Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis
spellingShingle Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis
Marzochi, Mauro Célio de Almeida
Leishmania (Viannia) braziliensis
Mucocutaneous leishmaniasis
Parasite persistence
Human migrations
Dogs
Expansion in the Americas
Anthroponosis
Control
title_short Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis
title_full Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis
title_fullStr Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis
title_full_unstemmed Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis
title_sort Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis
author Marzochi, Mauro Célio de Almeida
author_facet Marzochi, Mauro Célio de Almeida
Marzochi, Keyla Belizia Feldman
Fagundes, Aline
Schubach, Armando de Oliveira
Miranda, Luciana de Freitas Campos
Pacheco, Raquel da Silva
author_role author
author2 Marzochi, Keyla Belizia Feldman
Fagundes, Aline
Schubach, Armando de Oliveira
Miranda, Luciana de Freitas Campos
Pacheco, Raquel da Silva
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Marzochi, Mauro Célio de Almeida
Marzochi, Keyla Belizia Feldman
Fagundes, Aline
Schubach, Armando de Oliveira
Miranda, Luciana de Freitas Campos
Pacheco, Raquel da Silva
dc.subject.en.pt_BR.fl_str_mv Leishmania (Viannia) braziliensis
Mucocutaneous leishmaniasis
Parasite persistence
Human migrations
Dogs
Expansion in the Americas
Anthroponosis
Control
topic Leishmania (Viannia) braziliensis
Mucocutaneous leishmaniasis
Parasite persistence
Human migrations
Dogs
Expansion in the Americas
Anthroponosis
Control
description Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-12-17T12:57:08Z
dc.date.available.fl_str_mv 2021-12-17T12:57:08Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MARZOCHI, Mauro Célio de Almeida et al. Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis. Frontiers in Tropical Diseases, v. 2, n. 723017, p. 1-9, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/50473
dc.identifier.issn.pt_BR.fl_str_mv 2673-7515
dc.identifier.doi.none.fl_str_mv 10.3389/fitd.2021.723017
identifier_str_mv MARZOCHI, Mauro Célio de Almeida et al. Anthropogenic Dispersal of Leishmania (Viannia) braziliensis in the Americas: A Plausible Hypothesis. Frontiers in Tropical Diseases, v. 2, n. 723017, p. 1-9, 2021.
2673-7515
10.3389/fitd.2021.723017
url https://www.arca.fiocruz.br/handle/icict/50473
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/50473/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/50473/2/Anthropogenic_Aline_Fagundes_etal_INI_2021.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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