Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil

Detalhes bibliográficos
Autor(a) principal: Nonaka, Carolina Kymie Vasques
Data de Publicação: 2021
Outros Autores: Franco, Marília Miranda, Gräf, Tiago, Barcia, Camila Araújo de Lorenzo, Mendonça, Renata Naves de Ávila, Sousa, Karoline Almeida Felix de, Neiva, Leila Machado Costa, Fosenca, Vagner, Mendes, Ana Verena Almeida, Aguiar, Renato Santana de, Giovanetti, Marta, Souza, Bruno Solano de Freitas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/47610
Resumo: INOVA Fiocruz, Serrapilheira Institute, and D’Or Institute for Research and Education. M.G. is supported by Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro.
id CRUZ_50a81a88dd92ef086978abc352009151
oai_identifier_str oai:www.arca.fiocruz.br:icict/47610
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Nonaka, Carolina Kymie VasquesFranco, Marília MirandaGräf, TiagoBarcia, Camila Araújo de LorenzoMendonça, Renata Naves de ÁvilaSousa, Karoline Almeida Felix deNeiva, Leila Machado CostaFosenca, VagnerMendes, Ana Verena AlmeidaAguiar, Renato Santana deGiovanetti, MartaSouza, Bruno Solano de Freitas2021-06-10T13:11:00Z2021-06-10T13:11:00Z2021NONAKA, Carolina Kymie Vasques et al. Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil. Emerging Infectious Diseases, v. 27, n. 5, May 2021.1080-6040https://www.arca.fiocruz.br/handle/icict/4761010.3201/eid2705.210191INOVA Fiocruz, Serrapilheira Institute, and D’Or Institute for Research and Education. M.G. is supported by Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro.Instituto D'Or de Ensino e Pesquisa. Salvador, BA, Brasil / Hospital São Rafael. Centro de Biotecnologia e Terapia Celular. Salvador, BA, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.São Rafael Hospital. Department of Infectology. Salvador, BA, Brazil.Ministério da Saúde. Coordenação Geral dos Laboratórios de Saúde Pública. Brasília, DF, Brasil / University of KwaZulu-Natal. College of Health Sciences. Durban, South Africa / Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil.Hospital São Rafael. Departamento de Infectologia. Salvador, BA, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil / University Campus Bio-Medico of Rome. Unit of Medical Statistics and Molecular Epidemiology. Rome, Italy.Instituto D'Or de Ensino e Pesquisa. Salvador, BA, Brasil / Hospital São Rafael. Centro de Biotecnologia e Terapia Celular. Salvador, BA, Brasil.Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct virus lineages in Brazil harboring the E484K mutation, a variant associated with escape from neutralizing antibodies.engCenters for Disease Control and PreventionCoronavirusSíndrome Respiratória Aguda GraveMutaçãoSars-CoV-2CoronavirusSevere Acute Respiratory SyndromeMutationSARS-Cov-2Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/47610/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALNonaka, Carolina Kymie Vasques Genomic....pdfNonaka, Carolina Kymie Vasques Genomic....pdfapplication/pdf1354161https://www.arca.fiocruz.br/bitstream/icict/47610/2/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Genomic....pdf44ecb72ccdaabbdcced0d2a7b316aab2MD52TEXTNonaka, Carolina Kymie Vasques Genomic....pdf.txtNonaka, Carolina Kymie Vasques Genomic....pdf.txtExtracted texttext/plain12712https://www.arca.fiocruz.br/bitstream/icict/47610/3/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Genomic....pdf.txt66efb0cb8f83e0f5be1fd9799896c5a8MD53icict/476102023-09-04 10:53:59.003oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-04T13:53:59Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en.fl_str_mv Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil
title Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil
spellingShingle Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil
Nonaka, Carolina Kymie Vasques
Coronavirus
Síndrome Respiratória Aguda Grave
Mutação
Sars-CoV-2
Coronavirus
Severe Acute Respiratory Syndrome
Mutation
SARS-Cov-2
title_short Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil
title_full Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil
title_fullStr Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil
title_full_unstemmed Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil
title_sort Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil
author Nonaka, Carolina Kymie Vasques
author_facet Nonaka, Carolina Kymie Vasques
Franco, Marília Miranda
Gräf, Tiago
Barcia, Camila Araújo de Lorenzo
Mendonça, Renata Naves de Ávila
Sousa, Karoline Almeida Felix de
Neiva, Leila Machado Costa
Fosenca, Vagner
Mendes, Ana Verena Almeida
Aguiar, Renato Santana de
Giovanetti, Marta
Souza, Bruno Solano de Freitas
author_role author
author2 Franco, Marília Miranda
Gräf, Tiago
Barcia, Camila Araújo de Lorenzo
Mendonça, Renata Naves de Ávila
Sousa, Karoline Almeida Felix de
Neiva, Leila Machado Costa
Fosenca, Vagner
Mendes, Ana Verena Almeida
Aguiar, Renato Santana de
Giovanetti, Marta
Souza, Bruno Solano de Freitas
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Nonaka, Carolina Kymie Vasques
Franco, Marília Miranda
Gräf, Tiago
Barcia, Camila Araújo de Lorenzo
Mendonça, Renata Naves de Ávila
Sousa, Karoline Almeida Felix de
Neiva, Leila Machado Costa
Fosenca, Vagner
Mendes, Ana Verena Almeida
Aguiar, Renato Santana de
Giovanetti, Marta
Souza, Bruno Solano de Freitas
dc.subject.other.pt_BR.fl_str_mv Coronavirus
Síndrome Respiratória Aguda Grave
Mutação
Sars-CoV-2
topic Coronavirus
Síndrome Respiratória Aguda Grave
Mutação
Sars-CoV-2
Coronavirus
Severe Acute Respiratory Syndrome
Mutation
SARS-Cov-2
dc.subject.en.en.fl_str_mv Coronavirus
Severe Acute Respiratory Syndrome
Mutation
SARS-Cov-2
description INOVA Fiocruz, Serrapilheira Institute, and D’Or Institute for Research and Education. M.G. is supported by Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-06-10T13:11:00Z
dc.date.available.fl_str_mv 2021-06-10T13:11:00Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv NONAKA, Carolina Kymie Vasques et al. Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil. Emerging Infectious Diseases, v. 27, n. 5, May 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/47610
dc.identifier.issn.pt_BR.fl_str_mv 1080-6040
dc.identifier.doi.pt_BR.fl_str_mv 10.3201/eid2705.210191
identifier_str_mv NONAKA, Carolina Kymie Vasques et al. Genomic evidence of SARS-CoV-2 reinfection involving E484K spike mutation, Brazil. Emerging Infectious Diseases, v. 27, n. 5, May 2021.
1080-6040
10.3201/eid2705.210191
url https://www.arca.fiocruz.br/handle/icict/47610
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Centers for Disease Control and Prevention
publisher.none.fl_str_mv Centers for Disease Control and Prevention
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/47610/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/47610/2/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Genomic....pdf
https://www.arca.fiocruz.br/bitstream/icict/47610/3/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Genomic....pdf.txt
bitstream.checksum.fl_str_mv 36b51ef91c52b5338d9d29ba0cc807bc
44ecb72ccdaabbdcced0d2a7b316aab2
66efb0cb8f83e0f5be1fd9799896c5a8
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813008989340827648