Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia

Detalhes bibliográficos
Autor(a) principal: Totino, Paulo R. R.
Data de Publicação: 2010
Outros Autores: Magalhães, Aline D., Silva, Luciene A., Banic, Dalma M., Daniel-Ribeiro, Cláudio Tadeu, Cruz, Maria de Fátima Ferreira da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/25962
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.
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spelling Totino, Paulo R. R.Magalhães, Aline D.Silva, Luciene A.Banic, Dalma M.Daniel-Ribeiro, Cláudio TadeuCruz, Maria de Fátima Ferreira da2018-04-19T16:36:11Z2018-04-19T16:36:11Z2010TOTINO, Paulo Renato R. et al. Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia. Malaria Journal, v.9:150, 5p, 2010.1475-2875https://www.arca.fiocruz.br/handle/icict/2596210.1186/1475-2875-9-350engBioMed CentralMaláriaAnemiaPlasmodium falciparumMalariaAnaemiaPlasmodium falciparumApoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.Severe anaemia is a common complication of Plasmodium falciparum malaria in hyperendemic regions. Premature elimination of non-parasitized red blood cells (nRBC) has been considered as one mechanism involved in the genesis of severe malaria anaemia. It has been reported that apoptosis can occur in RBC and, consequently, this cell death process could contribute to anaemia. This study was performed to evaluate the susceptibility of nRBC to apoptosis in a malaria anaemia murine model.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/25962/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALalined_magalhaes_etal_IOC_2010.pdfalined_magalhaes_etal_IOC_2010.pdfapplication/pdf636299https://www.arca.fiocruz.br/bitstream/icict/25962/2/alined_magalhaes_etal_IOC_2010.pdfd553db5341bd8b73a59179dcb4659028MD52TEXTalined_magalhaes_etal_IOC_2010.pdf.txtalined_magalhaes_etal_IOC_2010.pdf.txtExtracted texttext/plain23085https://www.arca.fiocruz.br/bitstream/icict/25962/3/alined_magalhaes_etal_IOC_2010.pdf.txtf3f2116a8900273cf72a88aa809feb6eMD53icict/259622018-12-28 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dc.title.pt_BR.fl_str_mv Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia
title Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia
spellingShingle Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia
Totino, Paulo R. R.
Malária
Anemia
Plasmodium falciparum
Malaria
Anaemia
Plasmodium falciparum
title_short Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia
title_full Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia
title_fullStr Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia
title_full_unstemmed Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia
title_sort Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia
author Totino, Paulo R. R.
author_facet Totino, Paulo R. R.
Magalhães, Aline D.
Silva, Luciene A.
Banic, Dalma M.
Daniel-Ribeiro, Cláudio Tadeu
Cruz, Maria de Fátima Ferreira da
author_role author
author2 Magalhães, Aline D.
Silva, Luciene A.
Banic, Dalma M.
Daniel-Ribeiro, Cláudio Tadeu
Cruz, Maria de Fátima Ferreira da
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Totino, Paulo R. R.
Magalhães, Aline D.
Silva, Luciene A.
Banic, Dalma M.
Daniel-Ribeiro, Cláudio Tadeu
Cruz, Maria de Fátima Ferreira da
dc.subject.other.pt_BR.fl_str_mv Malária
Anemia
Plasmodium falciparum
topic Malária
Anemia
Plasmodium falciparum
Malaria
Anaemia
Plasmodium falciparum
dc.subject.en.pt_BR.fl_str_mv Malaria
Anaemia
Plasmodium falciparum
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Malária. Rio de Janeiro, RJ. Brasil.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2018-04-19T16:36:11Z
dc.date.available.fl_str_mv 2018-04-19T16:36:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TOTINO, Paulo Renato R. et al. Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia. Malaria Journal, v.9:150, 5p, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/25962
dc.identifier.issn.pt_BR.fl_str_mv 1475-2875
dc.identifier.doi.none.fl_str_mv 10.1186/1475-2875-9-350
identifier_str_mv TOTINO, Paulo Renato R. et al. Apoptosis of non-parasitized red blood cells in malaria: a putative mechanism involved in the pathogenesis of anaemia. Malaria Journal, v.9:150, 5p, 2010.
1475-2875
10.1186/1475-2875-9-350
url https://www.arca.fiocruz.br/handle/icict/25962
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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