Molecular evidence of horizontal transmission of hepatitis C virus within couples
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2010 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/27291 |
Resumo: | Queiróz, Artur Trancoso Lopo de. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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Mello, Isabel Maria Vicente Guedes de CarvalhoFilho, José Eymard MedeirosGouvêa, Michele Soares GomesMalta, Fernanda de MelloQueiróz, Artur Trancoso Lopo dePinho, João Renato RebelloCarrilho, Flair José2018-07-04T18:14:20Z2018-07-04T18:14:20Z2010MELLO, I. M. V. G. C. et al. Molecular evidence of horizontal transmission of hepatitis C virus within couples. Journal of General Virology, v. 91, p. 691–696, 2010.0022-1317https://www.arca.fiocruz.br/handle/icict/2729110.1099/vir.0.015594-0Queiróz, Artur Trancoso Lopo de. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.Alves de Queiroz Family Fund for Research, Instituto Adolfo Lutz and Instituto Butantan.Instituto Butantan. Laboratório de Imunologia Viral. São Paulo, SP, Brasil / University of São Paulo School of Medicine. Department of Gastroenterology. São Paulo, SP, BrasilUniversity of São Paulo School of Medicine. Department of Gastroenterology. São Paulo, SP, BrasilUniversity of São Paulo School of Medicine. Department of Gastroenterology. São Paulo, SP, BrasilUniversity of São Paulo School of Medicine. Department of Gastroenterology. São Paulo, SP, BrasilUniversidade de São Paulo. Instituto de Biociências. São Paulo, SP, BrasilUniversity of São Paulo School of Medicine. Department of Gastroenterology. São Paulo, SP, BrasilUniversity of São Paulo School of Medicine. Department of Gastroenterology. São Paulo, SP, BrasilHepatitis C virus (HCV) transmission has decreased with the adoption of universal blood donor screening and social policies to reduce the risk of infection in intravenous drug users, but remains a worldwide health problem. The objective of this study was to evaluate the phylogenetic relationships among sequences from different HCV genomic regions from sexual partners of infected patients. Nine couples with a stable relationship and without other risk factors for HCV infection and 42 control patients were selected, and the NS3 and NS5B regions were analysed. Phylogenetic analysis showed that viruses from five of the couples had a common origin, clustering in the same monophyletic group, with bootstrap values greater than 70. For the other couples, monophyletic groups were observed, but without bootstrap support. Thus, using two different viral genome regions, a common source of infection was observed in both members of five couples. These data strongly support HCV transmission within couples.engMicrobiology SocietyHepatite CHepacivirusTransmissão de Doenças InfecciosasRNA ViralFilogeniaHepatitis CHepacivirusDisease Transmission, InfectiousRNA, ViralPhylogenyMolecular evidence of horizontal transmission of hepatitis C virus within couplesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/27291/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCarvalho- Mello IM Molecular evidence of horizontal....pdfCarvalho- Mello IM Molecular evidence of horizontal....pdfapplication/pdf217167https://www.arca.fiocruz.br/bitstream/icict/27291/2/Carvalho-%20Mello%20IM%20Molecular%20evidence%20of%20horizontal....pdfc92614b91fded9fd03daab5c500e14adMD52TEXTCarvalho- Mello IM Molecular evidence of horizontal....pdf.txtCarvalho- Mello IM Molecular evidence of horizontal....pdf.txtExtracted texttext/plain27166https://www.arca.fiocruz.br/bitstream/icict/27291/3/Carvalho-%20Mello%20IM%20Molecular%20evidence%20of%20horizontal....pdf.txt025c3e7de0a142e2de299144d00f1d17MD53icict/272912023-03-15 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| dc.title.pt_BR.fl_str_mv |
Molecular evidence of horizontal transmission of hepatitis C virus within couples |
| title |
Molecular evidence of horizontal transmission of hepatitis C virus within couples |
| spellingShingle |
Molecular evidence of horizontal transmission of hepatitis C virus within couples Mello, Isabel Maria Vicente Guedes de Carvalho Hepatite C Hepacivirus Transmissão de Doenças Infecciosas RNA Viral Filogenia Hepatitis C Hepacivirus Disease Transmission, Infectious RNA, Viral Phylogeny |
| title_short |
Molecular evidence of horizontal transmission of hepatitis C virus within couples |
| title_full |
Molecular evidence of horizontal transmission of hepatitis C virus within couples |
| title_fullStr |
Molecular evidence of horizontal transmission of hepatitis C virus within couples |
| title_full_unstemmed |
Molecular evidence of horizontal transmission of hepatitis C virus within couples |
| title_sort |
Molecular evidence of horizontal transmission of hepatitis C virus within couples |
| author |
Mello, Isabel Maria Vicente Guedes de Carvalho |
| author_facet |
Mello, Isabel Maria Vicente Guedes de Carvalho Filho, José Eymard Medeiros Gouvêa, Michele Soares Gomes Malta, Fernanda de Mello Queiróz, Artur Trancoso Lopo de Pinho, João Renato Rebello Carrilho, Flair José |
| author_role |
author |
| author2 |
Filho, José Eymard Medeiros Gouvêa, Michele Soares Gomes Malta, Fernanda de Mello Queiróz, Artur Trancoso Lopo de Pinho, João Renato Rebello Carrilho, Flair José |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Mello, Isabel Maria Vicente Guedes de Carvalho Filho, José Eymard Medeiros Gouvêa, Michele Soares Gomes Malta, Fernanda de Mello Queiróz, Artur Trancoso Lopo de Pinho, João Renato Rebello Carrilho, Flair José |
| dc.subject.other.pt_BR.fl_str_mv |
Hepatite C Hepacivirus Transmissão de Doenças Infecciosas RNA Viral Filogenia |
| topic |
Hepatite C Hepacivirus Transmissão de Doenças Infecciosas RNA Viral Filogenia Hepatitis C Hepacivirus Disease Transmission, Infectious RNA, Viral Phylogeny |
| dc.subject.en.pt_BR.fl_str_mv |
Hepatitis C Hepacivirus Disease Transmission, Infectious RNA, Viral Phylogeny |
| description |
Queiróz, Artur Trancoso Lopo de. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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2010 |
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2010 |
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2018-07-04T18:14:20Z |
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2018-07-04T18:14:20Z |
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info:eu-repo/semantics/article |
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MELLO, I. M. V. G. C. et al. Molecular evidence of horizontal transmission of hepatitis C virus within couples. Journal of General Virology, v. 91, p. 691–696, 2010. |
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https://www.arca.fiocruz.br/handle/icict/27291 |
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0022-1317 |
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10.1099/vir.0.015594-0 |
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MELLO, I. M. V. G. C. et al. Molecular evidence of horizontal transmission of hepatitis C virus within couples. Journal of General Virology, v. 91, p. 691–696, 2010. 0022-1317 10.1099/vir.0.015594-0 |
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