Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/2785 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil |
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Lins, LilianeAlmeida, HerbertVitvitski, LudmilaCarmo, Theomira Mauadie de AzevedoParaná, RaymundoReis, Mitermayer Galvão dos2011-07-28T18:27:28Z2011-07-28T18:27:28Z2005LINS, L. et al. Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load. Journal of Medical Virology, v. 77, n. 2, p. 216-220, 2005.0146-6615https://www.arca.fiocruz.br/handle/icict/278510.1002/jmv.20438engHepacivirusRNA ViralSalivaAnticorpos Anti-HepatiteGenes ViraisCarga ViralHepacivirusRNA ViralSalivaAnticorpos Anti-HepatiteDetection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Loadinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, BrazilINSERM U271. Lyon, FranceFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilHepatitis C is a worldwide public health problem and its transmission is clearly associated with the parenteral route, however, the virus has also been isolated from other body fluids. Hepatitis C virus (HCV) RNA has been detected in saliva, yet the relationship between HCV and oral pathology is not clearly understood. Therefore, an investigation on HCV-RNA in saliva and its correlation with oral pathology was undertaken. Saliva and blood samples were collected from 50 anti-HCV positive patients and from 25 patients with non-HCV chronic liver disease. HCV-RNA was detected in all of the saliva samples from the HCV positive group. None of the saliva or serum samples from the non-HCV group were positive for HCV-RNA. The patients were examined for dental and oral health (dentate, partially dentate, edentulous, evidence of gum disease, or mucosal lesions); however, no correlation was found between HCV-RNA in saliva, oral health, and viral load. These results suggest that HCV-RNA presence in saliva is independent of the viral load and the oral pathology of HCV positive individualsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALLins L Detection of hepatitis C virus....pdfLins L Detection of hepatitis C virus....pdfapplication/pdf90877https://www.arca.fiocruz.br/bitstream/icict/2785/1/Lins%20L%20Detection%20of%20hepatitis%20C%20virus....pdfee233685ab67836fa1632e6a53a2d76bMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/2785/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTLins L Detection of hepatitis C virus....pdf.txtLins L Detection of hepatitis C virus....pdf.txtExtracted texttext/plain22456https://www.arca.fiocruz.br/bitstream/icict/2785/5/Lins%20L%20Detection%20of%20hepatitis%20C%20virus....pdf.txtd4dfcdb41aa8456b00e8f5c1a85b400bMD55THUMBNAILLins L Detection of hepatitis C virus....pdf.jpgLins L Detection of hepatitis C virus....pdf.jpgGenerated Thumbnailimage/jpeg2263https://www.arca.fiocruz.br/bitstream/icict/2785/4/Lins%20L%20Detection%20of%20hepatitis%20C%20virus....pdf.jpgd2602eb75fc424d526044ba9848edd93MD54icict/27852023-03-15 14:33:00.364oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load |
title |
Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load |
spellingShingle |
Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load Lins, Liliane Hepacivirus RNA Viral Saliva Anticorpos Anti-Hepatite Genes Virais Carga Viral Hepacivirus RNA Viral Saliva Anticorpos Anti-Hepatite |
title_short |
Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load |
title_full |
Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load |
title_fullStr |
Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load |
title_full_unstemmed |
Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load |
title_sort |
Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load |
author |
Lins, Liliane |
author_facet |
Lins, Liliane Almeida, Herbert Vitvitski, Ludmila Carmo, Theomira Mauadie de Azevedo Paraná, Raymundo Reis, Mitermayer Galvão dos |
author_role |
author |
author2 |
Almeida, Herbert Vitvitski, Ludmila Carmo, Theomira Mauadie de Azevedo Paraná, Raymundo Reis, Mitermayer Galvão dos |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Lins, Liliane Almeida, Herbert Vitvitski, Ludmila Carmo, Theomira Mauadie de Azevedo Paraná, Raymundo Reis, Mitermayer Galvão dos |
dc.subject.other.pt_BR.fl_str_mv |
Hepacivirus RNA Viral Saliva Anticorpos Anti-Hepatite Genes Virais Carga Viral |
topic |
Hepacivirus RNA Viral Saliva Anticorpos Anti-Hepatite Genes Virais Carga Viral Hepacivirus RNA Viral Saliva Anticorpos Anti-Hepatite |
dc.subject.decs.pt_BR.fl_str_mv |
Hepacivirus RNA Viral Saliva Anticorpos Anti-Hepatite |
description |
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil |
publishDate |
2005 |
dc.date.issued.fl_str_mv |
2005 |
dc.date.accessioned.fl_str_mv |
2011-07-28T18:27:28Z |
dc.date.available.fl_str_mv |
2011-07-28T18:27:28Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
LINS, L. et al. Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load. Journal of Medical Virology, v. 77, n. 2, p. 216-220, 2005. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/2785 |
dc.identifier.issn.none.fl_str_mv |
0146-6615 |
dc.identifier.doi.none.fl_str_mv |
10.1002/jmv.20438 |
identifier_str_mv |
LINS, L. et al. Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load. Journal of Medical Virology, v. 77, n. 2, p. 216-220, 2005. 0146-6615 10.1002/jmv.20438 |
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https://www.arca.fiocruz.br/handle/icict/2785 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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